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VeracyteD
Nasdaq / Pharmaceuticals, Biotechnology & Life Sciences
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2026-08-01
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Investor releaseQuarter not tagged2026-08-01

Veracyte Q2 Earnings Call Highlights

MarketBeat
Interested in Veracyte, Inc.? Here are five stocks we like better. Veracyte reported strong Q2 results, with revenue up 15% to $150.3 million, testing revenue up 19% to $145.7 million, and adjusted EBITDA of $44 million. The company generated $45.8 million in operating cash flow and ended the quarter with $485.2 million in cash and short-term investments. The company raised its 2026 revenue outlook to $590 million–$596 million, representing 14%–15% growth, while maintaining its expectation for an adjusted EBITDA margin above 26%. Veracyte launched its Prosigna breast cancer test and TrueMRD bladder cancer recurrence-monitoring test; neither is included in current 2026 guidance. Core products also performed well, with Decipher Prostate revenue up 20% and Afirma revenue up 18%. Veracyte (NASDAQ:VCYT) reported second-quarter 2026 revenue growth of 15% and raised its full-year revenue outlook, while highlighting the launches of its Prosigna LDT breast cancer test and TrueMRD recurrence-monitoring test for muscle-invasive bladder cancer. Chief Executive Officer Marc Stapley called the quarter a milestone for the company, saying the new products expand Veracyte’s portfolio across the cancer-care continuum. The company also said it is approaching the milestone of serving its one millionth patient. → Why SK hynix Could Be the Best AI Chip Stock to Buy Now Total revenue was $150.3 million, up 15% from the prior-year period, while testing revenue increased 19% to $145.7 million, Chief Financial Officer Rebecca Chambers said. Total test volume rose 13% to about 51,000 tests, and testing volume increased 14% to 48,389 tests. Veracyte generated $45.8 million in cash from operations during the quarter and ended the period with $485.2 million in cash equivalents and short-term investments. GAAP net income was $25.5 million, while adjusted EBITDA totaled $44 million, or 29.2% of revenue. → Microsoft Just Flipped the AI Spending Narrative Overnight The company raised its 2026 total revenue guidance to a range of $590 million to $596 million, representing projected growth of 14% to 15%. Its prior outlook called for $582 million to $592 million in revenue. Testing revenue is now expected to be between $576 million and $582 million, representing growth of 17% to 18%. The forecast includes about $10 million in other testing revenue from cytology services and Decipher Bladder. →…Read full document

Interested in Veracyte, Inc.? Here are five stocks we like better. Veracyte reported strong Q2 results, with revenue up 15% to $150.3 million, testing revenue up 19% to $145.7 million, and adjusted EBITDA of $44 million. The company generated $45.8 million in operating cash flow and ended the quarter with $485.2 million in cash and short-term investments. The company raised its 2026 revenue outlook to $590 million–$596 million, representing 14%–15% growth, while maintaining its expectation for an adjusted EBITDA margin above 26%. Veracyte launched its Prosigna breast cancer test and TrueMRD bladder cancer recurrence-monitoring test; neither is included in current 2026 guidance. Core products also performed well, with Decipher Prostate revenue up 20% and Afirma revenue up 18%. Veracyte (NASDAQ:VCYT) reported second-quarter 2026 revenue growth of 15% and raised its full-year revenue outlook, while highlighting the launches of its Prosigna LDT breast cancer test and TrueMRD recurrence-monitoring test for muscle-invasive bladder cancer. Chief Executive Officer Marc Stapley called the quarter a milestone for the company, saying the new products expand Veracyte’s portfolio across the cancer-care continuum. The company also said it is approaching the milestone of serving its one millionth patient. → Why SK hynix Could Be the Best AI Chip Stock to Buy Now Total revenue was $150.3 million, up 15% from the prior-year period, while testing revenue increased 19% to $145.7 million, Chief Financial Officer Rebecca Chambers said. Total test volume rose 13% to about 51,000 tests, and testing volume increased 14% to 48,389 tests. Veracyte generated $45.8 million in cash from operations during the quarter and ended the period with $485.2 million in cash equivalents and short-term investments. GAAP net income was $25.5 million, while adjusted EBITDA totaled $44 million, or 29.2% of revenue. → Microsoft Just Flipped the AI Spending Narrative Overnight The company raised its 2026 total revenue guidance to a range of $590 million to $596 million, representing projected growth of 14% to 15%. Its prior outlook called for $582 million to $592 million in revenue. Testing revenue is now expected to be between $576 million and $582 million, representing growth of 17% to 18%. The forecast includes about $10 million in other testing revenue from cytology services and Decipher Bladder. → Carrier Earnings Could Send the Stock to a New All-Time High Chambers said the company continues to expect adjusted EBITDA margin of more than 26% for the year, despite investments behind growth initiatives. She said the higher revenue outlook reflects stronger-than-expected average selling prices and prior-period collections, or PPCs. Testing average selling price was $3,010, up 4% year over year and including about $4.5 million in PPCs. Normalized testing ASP, excluding PPCs, increased 3% to about $2,900. Non-GAAP gross margin rose 340 basis points to 74.9%. Testing gross margin rose 200 basis points to 76%, supported by workflow efficiencies, higher ASP and PPCs. Chambers said the company expects ASP to be slightly higher in 2026 than in 2025. However, she noted that Prosigna’s launch and reimbursement status could create a modest gross-margin headwind in the second half. Veracyte launched its Prosigna LDT in the United States following presentation of results from the OPTIMA trial at the American Society of Clinical Oncology meeting. Prosigna is designed to help guide treatment decisions for patients with estrogen receptor-positive, HER2-negative breast cancer by assessing recurrence risk over 10 years and likelihood of chemotherapy benefit. Stapley said the independent prospective Phase III OPTIMA trial enrolled more than 4,400 high-risk, early-stage breast cancer patients and met its primary endpoint. According to the company, the study showed that more than two-thirds of clinically high-risk patients may be able to avoid chemotherapy without compromising outcomes, including premenopausal women and patients with up to nine positive lymph nodes. The company said it is engaged with more than 100 institutions, including academic cancer centers, integrated health systems and regional oncology networks, regarding Prosigna adoption. Stapley said some organizations are evaluating use of the test across their breast cancer programs. During the question-and-answer session, Chief Commercial Officer John Leite said Prosigna has Medicare coverage through the company’s existing FDA-approved product. Veracyte is seeking a technical assessment for the centralized LDT version from MolDX, followed by pricing discussions. Leite said the company previously guided to pricing at the low end of about $2,500. The company is expanding its sales force earlier than originally planned in response to demand and is investing in electronic health record integration. Chambers said Veracyte expects to expand the Prosigna sales force from roughly 10 people to 15 by year-end. The company’s 2026 guidance does not include revenue from Prosigna or TrueMRD. Veracyte also launched TrueMRD for recurrence monitoring in muscle-invasive bladder cancer patients following radical cystectomy. The test secured Medicare reimbursement and is the company’s first commercial product on its minimal residual disease platform. Stapley said TrueMRD uses whole-genome sequencing for both the initial landmark test and subsequent surveillance testing. Decipher Prostate revenue increased 20% year over year, driven primarily by 17% volume growth and improved ASP, Stapley said. The company processed just under 30,000 Decipher Prostate tests during the quarter. Veracyte reduced its full-year Decipher volume expectation by approximately 1%, or slightly more than 1,000 tests, primarily due to lower expectations in low-risk disease. Stapley said most of that shortfall occurred during the second quarter and reflected changes to guidelines affecting active-surveillance testing rather than a loss of market share. Management said Decipher’s intermediate- and high-risk prostate cancer segments continue to show strong growth, supported by clinical evidence and guideline positioning. The company expects about 31,000 Decipher tests in the third quarter and 33,000 in the fourth quarter, while maintaining its expectation for roughly 20% Decipher revenue growth for the full year. Afirma delivered approximately 18,600 tests, representing 10% volume growth, while revenue rose 18%. The company attributed the performance to greater use among existing physicians, expansion of its ordering base, market-share gains, improved reimbursement and the V2 transcriptome workflow. Stapley said the workflow reduced Afirma’s no-result rate and contributed approximately 400 basis points of volume growth during the quarter. Veracyte raised its full-year Afirma revenue growth outlook to approximately 12% to 14%, including an anticipated no-result-rate benefit of about 3% for the year. Looking ahead, management said it plans to continue investing in evidence generation, product development, commercial execution and operational infrastructure. Stapley said the company sees opportunities for longer-term growth across Prosigna, TrueMRD, Decipher, Afirma and bladder cancer diagnostics. Veracyte, Inc is a genomic diagnostics company focused on improving diagnostic accuracy and patient care through advanced molecular testing. Founded in 2008 and headquartered in South San Francisco, California, the company develops and commercializes minimally invasive genomic tests that aid in the diagnosis of thyroid, lung and other diseases. Veracyte's proprietary platform analyzes gene expression patterns in clinical samples to help physicians make more informed treatment decisions, reducing unnecessary surgeries and improving patient outcomes. The company's flagship product, the Afirma Genomic Sequencing Classifier, is designed to assess thyroid nodules with indeterminate cytology, helping clinicians distinguish benign from suspicious nodules. This instant news alert was generated by narrative science technology and financial data from MarketBeat in order to provide readers with the fastest reporting and unbiased coverage. Please send any questions or comments about this story to [email protected]. The article "Veracyte Q2 Earnings Call Highlights" was originally published by MarketBeat. View MarketBeat's top stocks for July 2026.

Investor releaseQuarter not tagged2026-07-31

Veracyte Inc (VCYT) (Q2 2026) Earnings Call Highlights: Record Revenue and Strategic Launches ...

GuruFocus.com
This article first appeared on GuruFocus. Total Revenue: $150.3 million in Q2 2026, up 15% year-over-year. Testing Revenue: $145.7 million, up 19% year-over-year. Total Volume: Approximately 51,000 tests, up 13% year-over-year. Testing Volume: 48,389 tests, up 14% year-over-year. Testing ASP: $3,010, up 4% year-over-year; normalized ASP up 3% to approximately $2,900 excluding prior period collections. Non-GAAP Gross Margin: 74.9%, up 340 basis points year-over-year; testing gross margin up 200 basis points to 76%. Non-GAAP Operating Expenses: $70 million, up 16% year-over-year. GAAP Net Income: $25.5 million in Q2 2026. Adjusted EBITDA: $44 million, or 29.2% of revenue, up 23% year-over-year. Cash Flow: $45.8 million generated from operations; ended quarter with $485.2 million in cash, cash equivalents, and short-term investments. Decipher Prostate Revenue: Up 20% year-over-year, driven by 17% volume growth and improved ASP; just under 30,000 tests resulted in Q2. Affirma Volume: Approximately 18,600 tests, up 10% year-over-year; revenue up 18%. Full-Year 2026 Revenue Guidance: Raised to $590 million to $596 million, representing 14% to 15% growth. Full-Year 2026 Testing Revenue Guidance: $576 million to $582 million, representing 17% to 18% growth. Full-Year 2026 Adjusted EBITDA Guidance: Greater than 26%. Warning! GuruFocus has detected 7 Warning Sign with VCYT. Is VCYT fairly valued? Test your thesis with our free DCF calculator. Release Date: July 30, 2026 For the complete transcript of the earnings call, please refer to the full earnings call transcript. Launched Prosigna LDT and TrueMRD for MIBC, expanding portfolio into breast cancer and MRD markets. Delivered strong Q2 2026 results with 15% total revenue growth and 19% testing revenue growth. Achieved industry-leading profitability with adjusted EBITDA margin of 29.2%, above the 25% long-term target. Decipher Prostate grew 20% year-over-year, driven by strong volume and ASP gains, with record orders per physician. Affirma continued to gain market share with 10% volume growth and 18% revenue growth, supported by improved no-result rates. Raised full-year 2026 revenue guidance to $590-$596 million, reflecting confidence in growth. Prosigna has strong clinical evidence from the OPTIMA trial, including Level 1A data for premenopausal and node-positive patients. TrueMRD platform is extensible to multiple…Read full document

This article first appeared on GuruFocus. Total Revenue: $150.3 million in Q2 2026, up 15% year-over-year. Testing Revenue: $145.7 million, up 19% year-over-year. Total Volume: Approximately 51,000 tests, up 13% year-over-year. Testing Volume: 48,389 tests, up 14% year-over-year. Testing ASP: $3,010, up 4% year-over-year; normalized ASP up 3% to approximately $2,900 excluding prior period collections. Non-GAAP Gross Margin: 74.9%, up 340 basis points year-over-year; testing gross margin up 200 basis points to 76%. Non-GAAP Operating Expenses: $70 million, up 16% year-over-year. GAAP Net Income: $25.5 million in Q2 2026. Adjusted EBITDA: $44 million, or 29.2% of revenue, up 23% year-over-year. Cash Flow: $45.8 million generated from operations; ended quarter with $485.2 million in cash, cash equivalents, and short-term investments. Decipher Prostate Revenue: Up 20% year-over-year, driven by 17% volume growth and improved ASP; just under 30,000 tests resulted in Q2. Affirma Volume: Approximately 18,600 tests, up 10% year-over-year; revenue up 18%. Full-Year 2026 Revenue Guidance: Raised to $590 million to $596 million, representing 14% to 15% growth. Full-Year 2026 Testing Revenue Guidance: $576 million to $582 million, representing 17% to 18% growth. Full-Year 2026 Adjusted EBITDA Guidance: Greater than 26%. Warning! GuruFocus has detected 7 Warning Sign with VCYT. Is VCYT fairly valued? Test your thesis with our free DCF calculator. Release Date: July 30, 2026 For the complete transcript of the earnings call, please refer to the full earnings call transcript. Launched Prosigna LDT and TrueMRD for MIBC, expanding portfolio into breast cancer and MRD markets. Delivered strong Q2 2026 results with 15% total revenue growth and 19% testing revenue growth. Achieved industry-leading profitability with adjusted EBITDA margin of 29.2%, above the 25% long-term target. Decipher Prostate grew 20% year-over-year, driven by strong volume and ASP gains, with record orders per physician. Affirma continued to gain market share with 10% volume growth and 18% revenue growth, supported by improved no-result rates. Raised full-year 2026 revenue guidance to $590-$596 million, reflecting confidence in growth. Prosigna has strong clinical evidence from the OPTIMA trial, including Level 1A data for premenopausal and node-positive patients. TrueMRD platform is extensible to multiple tumor types, offering long-term growth potential. Strong cash generation with $45.8 million from operations and $485.2 million in cash. Expanding sales force for Prosigna ahead of plan due to high demand and engagement from over 100 institutions. Reduced Decipher volume guidance by approximately 1% (1,000 tests) due to lower-than-expected growth in low-risk setting. Prosigna and TrueMRD revenue contributions are excluded from 2026 guidance due to lack of Medicare reimbursement for Prosigna and early launch stage. Prosigna launch faces headwinds from EMR integration and reimbursement uncertainties, with Medicare coverage still pending. Low-risk Decipher growth is only single-digit, impacted by NCCN guideline changes, limiting near-term expansion. Increased operating expenses by 16% year-over-year, driven by investments in launches and R&D, which may pressure margins. TrueMRD is in early commercialization stages with no revenue contribution expected this year, limiting near-term impact. Prosigna adoption may be slower due to the need for physician education and workflow integration, despite early enthusiasm. Affirma faces a harder comparison next year due to benefits from no-result rate improvements and PPCs in 2026. Guidance assumes no PPCs in the back half, which could lead to volatility if collections are lower than expected. Potential for increased competition in the breast cancer testing market, though not explicitly mentioned, remains a risk. Q: With the lower Decipher guidance of about 1,000 tests, are you seeing a threat specifically from AI-based testing, and how do you view the future workflow between AI and molecular testing? A: Marc Stapley (CEO) clarified that the reduction is not due to AI competition but is isolated to the low-risk category, driven by the 2024 NCCN guideline change that removed genomic testing for active surveillance. He noted that molecular and AI tests are complementary, measuring different biology, and physicians prefer more information. Rebecca Chambers (CFO) added that the strength in intermediate and high-risk categories remains robust, with low-risk representing an incremental growth opportunity for 2027-2029. Q: Can you provide more color on the commercial strategy for Prosigna, particularly regarding EMR integration, which has been cited as a headwind for adoption? A: John Leite (Global Chief Commercial Officer) acknowledged that EHR integration is critical for streamlining workflows and automating test ordering at scale. He stated that Veracyte is heavily investing in internal and external resources to integrate with as many practices as possible, leveraging existing efforts from the Decipher and Affirma businesses to accelerate Prosigna's integration. Q: What is the current penetration level for molecular diagnostics in the low-risk Decipher population, and where do you see it going over the next few years? A: Marc Stapley (CEO) stated that Veracyte is approximately 20% penetrated in the low-risk market, with penetration growing every quarter. He noted that for growth to accelerate into double digits, NCCN guideline inclusion will be needed, which is expected to be supported by multiple study readouts in 2027-2028. Rebecca Chambers (CFO) added that the company believes it can achieve at least 80% penetration in this segment, similar to other risk categories, highlighting significant white space. Q: Prosigna launched with commercial coverage but not MolDx. How are you managing patient access for Medicare beneficiaries, and what is your expectation for the MolDx timeline? A: John Leite (Global Chief Commercial Officer) explained that Prosigna already has Medicare coverage via the FDA-approved product, and the transition to the centralized LDT requires a tech assessment submission covering lab validation and bridging studies. He noted constructive exchanges with MolDx, expects approval "eminently," and guided that pricing could be around $2,500 at the low end. Q: The first two quarters have been meaningfully above the 26% adjusted EBITDA floor. How much of this is due to pulling forward investment, and can you provide color on the level of investment for Prosigna? A: Rebecca Chambers (CFO) stated that the company is expanding the Prosigna sales force from roughly 10 to 15 people this year, which is not a material cost. She emphasized that the guidance reflects a huge opportunity to invest in the pipeline across MRD, Decipher, Affirma, and Prosigna to drive higher future revenue growth. She also noted that PPCs, which are not guided, have been a significant contributor to outperformance, and Prosigna volume in the back half will create a slight gross margin headwind. Q: Was there any impact from ACA enrollment on Decipher low-risk volumes, and how should we think about the stable growth trajectory for Decipher overall? A: Marc Stapley (CEO) attributed the low-risk volume adjustment to comp issues and the NCCN guideline change, not ACA enrollment. He described Decipher's growth as highly predictable, with a trend line of approximately 20,000 tests per year plus or minus 1,000, and expects this to continue for the next couple of years. Rebecca Chambers (CFO) reminded that Affirma will face a harder comp next year due to the no-result rate benefit and outstanding PPCs in 2026. Q: Can you elaborate on the market traction for Prosigna since launch, particularly regarding the premenopausal and node-positive populations, and any volume numbers for this year or next? A: John Leite (Global Chief Commercial Officer) noted that the market responded very favorably to the Optima data, with the premenopausal and high node burden results being game-changing. He stated that while some physicians will start with these populations and expand, others are ready to switch entirely for logistical ease. He declined to provide volume guidance, stating the company needs more data over the coming months to guide accurately. Q: Can you update us on the TrueMRD pipeline, including when we should expect the next data readout and the next MolDx submission or indication? A: Marc Stapley (CEO) stated that the focus is currently on the muscle invasive bladder cancer launch as the landmark test to pilot the MRD approach. He mentioned that development and clinical teams are working on the next assays and evidence development, with a review of ongoing studies this week. He indicated that more details will be shared when the company is ready to launch additional tests, with the bladder test serving as the proof point for expansion. Q: Can you comment on early adoption of Prosigna, and do you believe the OPTIMA study results could be key to guideline inclusion? A: John Leite (Global Chief Commercial Officer) expressed satisfaction with early adoption, noting positive reactions from physicians and even direct patient inquiries. He confirmed that the OPTIMA trial is generally acknowledged as Level 1A evidence and should make its way to guidelines, but publication is the next milestone, which is out of the company's hands as it is an independent study. Q: Can you give an update on the Nightingale study and when we might hear intermediate data? A: Marc Stapley (CEO) reminded that the Nightingale study, for the peritoneonasal swab test, completed enrollment in August 2025. The company is about a year into patient follow-ups, and it will be a while before the study fully reads out. He characterized it as a longer-term growth driver, with results expected once all patients have been followed for at least one to two years. For the complete transcript of the earnings call, please refer to the full earnings call transcript.

Investor releaseQuarter not tagged2026-07-30

Veracyte Q2 Non-GAAP Earnings, Revenue Rise; 2026 Revenue Guidance Raised

MT Newswires

Veracyte (VCYT) reported Q2 non-GAAP earnings late Thursday of $0.54 per diluted share, up from $0.4

Investor releaseQuarter not tagged2026-07-30

Veracyte Announces Second Quarter 2026 Financial Results

GlobeNewswire
Grew total revenue to $150.3 million and testing revenue to $145.7 million, representing increases of 15% and 19% year-over-year, respectivelyConference call and webcast today at 4:30 p.m. ET SOUTH SAN FRANCISCO, Calif., July 30, 2026 (GLOBE NEWSWIRE) -- Veracyte, Inc. (Nasdaq: VCYT), a leading cancer diagnostics company, today announced financial results for the second quarter ended June 30, 2026. “Q2 was a milestone quarter for Veracyte as we launched two new products, Prosigna LDT and TrueMRD for MIBC, while also delivering strong double-digit revenue growth, profitability and cash generation,” said Marc Stapley, Veracyte’s chief executive officer. “These launches meaningfully expand our ability to serve more patients across the cancer care continuum and, combined with the strength of our core business, position us well to deliver durable double-digit growth.” Key Financial Highlights For the three-month period ended June 30, 2026, as compared to the same period in 2025: Increased total revenue by 15% to $150.3 million and testing revenue by 19% to $145.7 million, driven by Decipher growth of 20% to $91.9 million and Afirma growth of 18% to $51.2 million. Increased total volume by 13% to 50,967 tests and testing volume by 14% to 48,389 tests, driven by Decipher growth of 17% to approximately 29,700 tests and Afirma growth of 10% to approximately 18,600 tests. Recorded GAAP net income of $25.5 million, or 17.0% of revenue, and delivered adjusted EBITDA of $44.0 million, or 29.2% of revenue. Generated $45.8 million of cash from operations to end the quarter with $485.2 million of cash, cash equivalents, and short-term investments as of June 30, 2026. Key Business Highlights Launched the Prosigna Breast Test in the U.S. for patients diagnosed with early-stage hormone-receptor positive (HR+) breast cancer. Launched the TrueMRD Monitoring Test for patients with muscle-invasive bladder cancer (MIBC). Secured Medicare coverage for the TrueMRD Monitoring Test, representing the first Medicare coverage decision for the whole-genome sequencing-based TrueMRD platform. Further expanded the clinical evidence of our testing portfolio, including new predictive evidence from the OPTIMA trial supporting the clinical utility of Prosigna and the ENZAMET trial expanding the Decipher clinical evidence base. Together, Decipher and Afirma were featured in nearly 60 abstracts and…Read full document

Grew total revenue to $150.3 million and testing revenue to $145.7 million, representing increases of 15% and 19% year-over-year, respectivelyConference call and webcast today at 4:30 p.m. ET SOUTH SAN FRANCISCO, Calif., July 30, 2026 (GLOBE NEWSWIRE) -- Veracyte, Inc. (Nasdaq: VCYT), a leading cancer diagnostics company, today announced financial results for the second quarter ended June 30, 2026. “Q2 was a milestone quarter for Veracyte as we launched two new products, Prosigna LDT and TrueMRD for MIBC, while also delivering strong double-digit revenue growth, profitability and cash generation,” said Marc Stapley, Veracyte’s chief executive officer. “These launches meaningfully expand our ability to serve more patients across the cancer care continuum and, combined with the strength of our core business, position us well to deliver durable double-digit growth.” Key Financial Highlights For the three-month period ended June 30, 2026, as compared to the same period in 2025: Increased total revenue by 15% to $150.3 million and testing revenue by 19% to $145.7 million, driven by Decipher growth of 20% to $91.9 million and Afirma growth of 18% to $51.2 million. Increased total volume by 13% to 50,967 tests and testing volume by 14% to 48,389 tests, driven by Decipher growth of 17% to approximately 29,700 tests and Afirma growth of 10% to approximately 18,600 tests. Recorded GAAP net income of $25.5 million, or 17.0% of revenue, and delivered adjusted EBITDA of $44.0 million, or 29.2% of revenue. Generated $45.8 million of cash from operations to end the quarter with $485.2 million of cash, cash equivalents, and short-term investments as of June 30, 2026. Key Business Highlights Launched the Prosigna Breast Test in the U.S. for patients diagnosed with early-stage hormone-receptor positive (HR+) breast cancer. Launched the TrueMRD Monitoring Test for patients with muscle-invasive bladder cancer (MIBC). Secured Medicare coverage for the TrueMRD Monitoring Test, representing the first Medicare coverage decision for the whole-genome sequencing-based TrueMRD platform. Further expanded the clinical evidence of our testing portfolio, including new predictive evidence from the OPTIMA trial supporting the clinical utility of Prosigna and the ENZAMET trial expanding the Decipher clinical evidence base. Together, Decipher and Afirma were featured in nearly 60 abstracts and presentations during the quarter. A reconciliation of GAAP to non-GAAP financial measures has been provided in the tables included in this press release. An explanation of these measures is also included below under the heading "Note Regarding Use of Non-GAAP Financial Measures." Second Quarter 2026 Financial Results Total revenue for the second quarter of 2026 was $150.3 million, an increase of 15% compared to $130.2 million reported in the second quarter of 2025. Testing revenue was $145.7 million, an increase of 19% compared to $122.3 million in the second quarter of 2025, driven by growth in our Decipher Prostate and Afirma tests. Product revenue was $3.9 million, an increase of 7% compared to $3.6 million in the second quarter of 2025. Biopharmaceutical and other revenue was $0.8 million, an expected decrease compared to $4.3 million in the second quarter of 2025 given the restructuring and liquidation proceedings of Veracyte SAS. Total gross margin for the second quarter of 2026 was 72%, compared to 69% in the second quarter of 2025. Non-GAAP gross margin was 75%, compared to 72% in the second quarter of 2025. Operating expenses were $85.6 million for the second quarter of 2026 compared to $95.0 million in the second quarter of 2025. Non-GAAP operating expenses grew 16% to $70.0 million compared to $60.3 million in the second quarter of 2025. Net income for the second quarter of 2026 was $25.5 million, an increase of $26.5 million compared to the second quarter of 2025. Diluted net earnings per common share was $0.31, an improvement of $0.32 compared to the second quarter of 2025. Non-GAAP diluted net earnings per common share was $0.54, an increase of $0.10 compared to the second quarter of 2025. Net cash provided by operating activities in the first six months of 2026 was $81.0 million, an improvement of $42.1 million compared to the same period in 2025. Adjusted EBITDA for the second quarter of 2026 was $44.0 million, an improvement of 23% compared to the second quarter of 2025, representing 29.2% of revenue compared to 27.5% of revenue in the same period in 2025. 2026 Financial Outlook The company is raising 2026 total revenue guidance to $590 million to $596 million, or 14% to 15% growth, from prior guidance of $582 to $592 million, or 13% to 14% growth. The company is also raising testing revenue guidance to $576 million to $582 million, or 17% to 18% growth, from prior guidance of $570 million to $580 million, excluding the contribution from recently launched tests. The company continues to expect adjusted EBITDA margin to be greater than 26%. The company is unable to provide a quantitative reconciliation of expected adjusted EBITDA margin to expected GAAP net income margin, the most directly comparable forward-looking GAAP measure without unreasonable effort, because of the inherent difficulty in accurately forecasting the occurrence and financial impact of the various adjusting items necessary for such reconciliations that have not yet occurred, that are dependent on various factors, are out of the company’s control, or that cannot be reasonably predicted. Such adjustments include, but are not limited to, acquisition-related expenses, and other adjustments. Any associated estimate of these items and their impact on GAAP performance for the guidance period could vary materially. For more information on the non-GAAP financial measures, please refer to the section titled “Note Regarding Use of Non-GAAP Financial Measures” at the end of this press release. Conference Call and Webcast Details Veracyte will host a conference call and webcast today at 4:30 p.m. Eastern Time to discuss the company's financial results and provide a general business update. The conference call will be webcast live from the company’s website and will be available via the following link: https://edge.media-server.com/mmc/p/wwu2pyd7. The webcast should be accessed 10 minutes prior to the conference call start time. A replay of the webcast will be available for one year following the conclusion of the live broadcast and will be accessible on the company’s website at https://investor.veracyte.com/events-presentations. About Veracyte Veracyte (Nasdaq: VCYT) is a global diagnostics company with a vision to transform cancer care for patients around the world. The company’s molecular tests assess the unique biology of each patient’s tumor to help clinicians answer essential questions about cancer care. Veracyte’s Diagnostics Platform combines broad genomic and clinical data, advanced bioinformatics and AI, and a powerful evidence-generation engine to support continued innovation and pipeline development. The company’s portfolio includes the Afirma® Genomic Sequencing Classifier test, Decipher® Bladder Genomic Classifier test, Decipher® Prostate Genomic Classifier test, Prosigna® Breast Risk of Recurrence test, and the TrueMRD™ Monitoring Test for MIBC. For more information, visit Veracyte’s website or follow the company on LinkedIn or X (Twitter). Cautionary Note Regarding Forward-Looking Statements This press release contains forward-looking statements, including, but not limited to our statements related to our plans, objectives, and expectations (financial and otherwise), including with respect to our 2026 financial and operating results; and our intentions with respect to the development, launch, commercialization, adoption, and reimbursement of our tests and products. Forward-looking statements can be identified by words such as: “appears,” “anticipate,” “intend,” “plan,” “expect,” “believe,” “should,” “may,” “could,” “would,” “will,” “enable,” “positioned,” “offers,” “designed,” “ultimately,” “strategic,” “outlook,” “guidance,” and similar references to future periods. Actual results may differ materially from those projected or suggested in any forward-looking statements. These statements involve risks and uncertainties, which could cause actual results to differ materially from our predictions, and include, but are not limited to: our ability to launch, commercialize and receive reimbursement for our products; our ability to execute on our business strategies relating to the C2i Genomics acquisition, integration of the business and the realization of expected benefits and synergies; our ability to demonstrate the validity and utility of our genomic tests and biopharma and other offerings; our ability to continue executing on our business plan; our ability to continue to scale our global operations and enhance our internal control environment; the impact of the war in Ukraine and other regional conflicts on European economies; the impact of foreign currency fluctuations, volatile interest rates, inflation, the impact of legislation and policies enacted by the current U.S. administration; turmoil in the global banking and finance system; the ongoing conflict in the Middle East; and the performance and utility of our tests in the clinical environment. Additional factors that may impact these forward-looking statements can be found under the caption “Risk Factors” in our Annual Report on Form 10-K filed on February 26, 2026, as well as in other documents that we may file from time to time with the Securities and Exchange Commission. Copies of these documents, when available, may be found in the Investors section of our website at investor.veracyte.com. These forward-looking statements speak only as of the date hereof and, except as required by law, we specifically disclaim any obligation to update these forward-looking statements, whether as a result of new information, future events or otherwise. Note Regarding Use of Non-GAAP Financial Measures In addition to the financial measures prepared in accordance with generally accepted accounting principles (GAAP), this press release and the accompanying tables contain, and reference certain non‐GAAP results including non-GAAP gross margin, non-GAAP operating expenses, adjusted EBITDA, adjusted EBITDA as a percentage of revenue (also referred to as adjusted EBITDA margin), non-GAAP net income, and non-GAAP earnings per share (EPS) and non-GAAP weighted average shares outstanding. These non-GAAP financial measures are not meant to be considered superior to or a substitute for financial measures calculated in accordance with GAAP, and investors are cautioned that there are material limitations associated with the use of non-GAAP financial measures as an analytical tool. We use non-GAAP financial measures to internally evaluate and analyze financial results. We believe these non-GAAP financial measures provide investors with useful supplemental information about the financial performance of our business, enable comparison of financial results between periods where certain items may vary independent of business performance, and enable comparison of our financial results with other public companies, many of which present similar non-GAAP financial measures. However, the non-GAAP financial measures we present may be different from those used by other companies, including similarly titled measures. We compute these non-GAAP measures by adjusting the applicable GAAP measure to remove the impact of certain recurring and non-recurring charges and gains and to adjust for the impact of income tax items related to such adjustments to our GAAP financial statements. In particular, we exclude amortization of acquired intangible assets, acquisition-related expenses relating to our acquisitions of Decipher Biosciences, HalioDx and C2i Genomics, impairment charges associated with the nCounter license and other biopharmaceutical services related to HalioDx intangible assets, all stock-based compensation and certain costs related to restructuring from all of our non-GAAP financial measures as well as depreciation and income tax items from our adjusted EBITDA and adjusted EBITDA as a percentage of revenue. Beginning in the second quarter of 2024, we changed our non-GAAP policy to exclude all stock-based compensation to align with our peers and we have also excluded all stock-based compensation from our prior period non-GAAP financial measures. Management has excluded the effects of these items in non-GAAP financial measures to help investors gain a better understanding of the core operating results and future prospects of the company, consistent with how management measures and forecasts the company's performance, especially when comparing such results to previous periods or forecasts. The company encourages investors to carefully consider its results under GAAP, together with its supplemental non‐GAAP information and the reconciliation between these presentations. See “Reconciliation of U.S. GAAP to Non-GAAP Financial Measures” for a reconciliation of each non-GAAP measure presented to the comparable GAAP financial measure. 1. Cost of revenue, research and development, sales and marketing and general and administrative expenses include the following stock-based compensation related expenses: Investors:Kelly Gura [email protected] Media:Molly [email protected]+1-650-351-8780

Investor releaseQuarter not tagged2026-07-30

Veracyte (VCYT) Q2 Earnings and Revenues Surpass Estimates

Zacks
Veracyte (VCYT) came out with quarterly earnings of $0.54 per share, beating the Zacks Consensus Estimate of $0.43 per share. This compares to earnings of $0.44 per share a year ago. These figures are adjusted for non-recurring items. This quarterly report represents an earnings surprise of +25.58%. A quarter ago, it was expected that this molecular diagnostic company would post earnings of $0.34 per share when it actually produced earnings of $0.52, delivering a surprise of +52.94%. Over the last four quarters, the company has surpassed consensus EPS estimates four times. Veracyte, which belongs to the Zacks Medical - Instruments industry, posted revenues of $150.32 million for the quarter ended June 2026, surpassing the Zacks Consensus Estimate by 4.13%. This compares to year-ago revenues of $130.16 million. The company has topped consensus revenue estimates four times over the last four quarters. The sustainability of the stock's immediate price movement based on the recently-released numbers and future earnings expectations will mostly depend on management's commentary on the earnings call. Veracyte shares have added about 32.3% since the beginning of the year versus the S&P 500's gain of 6.9%. While Veracyte has outperformed the market so far this year, the question that comes to investors' minds is: what's next for the stock? There are no easy answers to this key question, but one reliable measure that can help investors address this is the company's earnings outlook. Not only does this include current consensus earnings expectations for the coming quarter(s), but also how these expectations have changed lately. Empirical research shows a strong correlation between near-term stock movements and trends in earnings estimate revisions. Investors can track such revisions by themselves or rely on a tried-and-tested rating tool like the Zacks Rank, which has an impressive track record of harnessing the power of earnings estimate revisions. Ahead of this earnings release, the estimate revisions trend for Veracyte was unfavorable. While the magnitude and direction of estimate revisions could change following the company's just-released earnings report, the current status translates into a Zacks Rank #4 (Sell) for the stock. So, the shares are expected to underperform the market in the near future. You can see the complete list of today's Zacks #1 Rank (Strong…Read full document

Veracyte (VCYT) came out with quarterly earnings of $0.54 per share, beating the Zacks Consensus Estimate of $0.43 per share. This compares to earnings of $0.44 per share a year ago. These figures are adjusted for non-recurring items. This quarterly report represents an earnings surprise of +25.58%. A quarter ago, it was expected that this molecular diagnostic company would post earnings of $0.34 per share when it actually produced earnings of $0.52, delivering a surprise of +52.94%. Over the last four quarters, the company has surpassed consensus EPS estimates four times. Veracyte, which belongs to the Zacks Medical - Instruments industry, posted revenues of $150.32 million for the quarter ended June 2026, surpassing the Zacks Consensus Estimate by 4.13%. This compares to year-ago revenues of $130.16 million. The company has topped consensus revenue estimates four times over the last four quarters. The sustainability of the stock's immediate price movement based on the recently-released numbers and future earnings expectations will mostly depend on management's commentary on the earnings call. Veracyte shares have added about 32.3% since the beginning of the year versus the S&P 500's gain of 6.9%. While Veracyte has outperformed the market so far this year, the question that comes to investors' minds is: what's next for the stock? There are no easy answers to this key question, but one reliable measure that can help investors address this is the company's earnings outlook. Not only does this include current consensus earnings expectations for the coming quarter(s), but also how these expectations have changed lately. Empirical research shows a strong correlation between near-term stock movements and trends in earnings estimate revisions. Investors can track such revisions by themselves or rely on a tried-and-tested rating tool like the Zacks Rank, which has an impressive track record of harnessing the power of earnings estimate revisions. Ahead of this earnings release, the estimate revisions trend for Veracyte was unfavorable. While the magnitude and direction of estimate revisions could change following the company's just-released earnings report, the current status translates into a Zacks Rank #4 (Sell) for the stock. So, the shares are expected to underperform the market in the near future. You can see the complete list of today's Zacks #1 Rank (Strong Buy) stocks here. It will be interesting to see how estimates for the coming quarters and the current fiscal year change in the days ahead. The current consensus EPS estimate is $0.44 on $149.11 million in revenues for the coming quarter and $1.85 on $583.57 million in revenues for the current fiscal year. Investors should be mindful of the fact that the outlook for the industry can have a material impact on the performance of the stock as well. In terms of the Zacks Industry Rank, Medical - Instruments is currently in the bottom 38% of the 250 plus Zacks industries. Our research shows that the top 50% of the Zacks-ranked industries outperform the bottom 50% by a factor of more than 2 to 1. One other stock from the same industry, Stereotaxis Inc. (STXS), is yet to report results for the quarter ended June 2026. The results are expected to be released on August 11. This company is expected to post quarterly loss of $0.03 per share in its upcoming report, which represents a year-over-year change of +40%. The consensus EPS estimate for the quarter has remained unchanged over the last 30 days. Stereotaxis Inc.'s revenues are expected to be $9.5 million, up 8% from the year-ago quarter. Want the latest recommendations from Zacks Investment Research? Today, you can download 7 Best Stocks for the Next 30 Days. Click to get this free report Veracyte, Inc. (VCYT) : Free Stock Analysis Report Stereotaxis Inc. (STXS) : Free Stock Analysis Report This article originally published on Zacks Investment Research (zacks.com). Zacks Investment Research

Investor releaseQuarter not tagged2026-07-30

Veracyte: Q2 Earnings Snapshot

Associated Press

SOUTH SAN FRANCISCO, Calif. (AP) — SOUTH SAN FRANCISCO, Calif. (AP) — Veracyte Inc. (VCYT) on Thursday reported second-quarter profit of $25.5 million. On a per-share basis, the South San Francisco, California-based company said it had profit of 31 cents. Earnings, adjusted for one-time gains and costs, came to 54 cents per share. The results beat Wall Street expectations. The average estimate of three analysts surveyed by Zacks Investment Research was for earnings of 43 cents per share. The molecular diagnostic company posted revenue of $150.3 million in the period, which also beat Street forecasts. Three analysts surveyed by Zacks expected $144.4 million. Veracyte expects full-year revenue in the range of $590 million to $596 million. _____ This story was generated by Automated Insights (http://automatedinsights.com/ap) using data from Zacks Investment Research. Access a Zacks stock report on VCYT at https://www.zacks.com/ap/VCYT

Investor releaseQuarter not tagged2026-07-30

Veracyte (VCYT) Rises with Upward Guidance Revision and Earnings Beat

Insider Monkey
Meridian Funds, managed by ArrowMark Partners, released its second-quarter 2026 investor letter for “Meridian Small Cap Growth Fund”. A copy of the letter can be downloaded here. The U.S. market saw a strong rally in the second quarter, fueled by easing geopolitical tensions, falling oil prices, and robust corporate earnings. Growth stocks, especially in technology and healthcare, led the charge, supported by AI-related investments from hyperscalers that added momentum. Meanwhile, traditional safe havens like gold declined. In this context, the Meridian Small Cap Growth Fund (the “Fund”) achieved a 21.54% return for the quarter ending June 30, 2026. This lagged behind its benchmark, the Russell 2000 Growth Index, which gained 25.71%, due to factor and style headwinds—as high-beta and momentum stocks soared, its lower-volatility, quality-focused holdings underperformed. The Fund continues to prioritize quality businesses, risk management, and downside protection, with portfolio adjustments driven by strategic allocation. In addition, please check the Fund’s top five holdings to know its best picks in 2026. In its Q2 2026 investor letter, Meridian Small Cap Growth Fund highlighted Veracyte, Inc. (NASDAQ:VCYT). Veracyte, Inc. (NASDAQ:VCYT), a global diagnostic company, contributed to the fund's performance during the quarter. On July 29, 2026, Veracyte, Inc. (NASDAQ:VCYT) closed at $55.71 per share, reflecting a market capitalization of $4.44 billion. Veracyte, Inc. (NASDAQ:VCYT) posted a one-month return of -2.40%, while its shares gained 136.96% over the past 52 weeks. Meridian Small Cap Growth Fund stated the following regarding Veracyte, Inc. (NASDAQ:VCYT) in its Q2 2026 investor update: Veracyte, Inc. (NASDAQ:VCYT) is not on our list of 40 Most Popular Stocks Among Hedge Funds Heading Into 2026. According to our database, 32 hedge fund portfolios held Veracyte, Inc. (NASDAQ:VCYT) at the end of the first quarter, up from 28 in the previous quarter. in Q1 2026, Veracyte, Inc. (NASDAQ:VCYT) reported revenue of $139.1 million, representing 21% year-over-year growth. While we acknowledge the potential of Veracyte, Inc. (NASDAQ:VCYT) as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you're looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and…Read full document

Meridian Funds, managed by ArrowMark Partners, released its second-quarter 2026 investor letter for “Meridian Small Cap Growth Fund”. A copy of the letter can be downloaded here. The U.S. market saw a strong rally in the second quarter, fueled by easing geopolitical tensions, falling oil prices, and robust corporate earnings. Growth stocks, especially in technology and healthcare, led the charge, supported by AI-related investments from hyperscalers that added momentum. Meanwhile, traditional safe havens like gold declined. In this context, the Meridian Small Cap Growth Fund (the “Fund”) achieved a 21.54% return for the quarter ending June 30, 2026. This lagged behind its benchmark, the Russell 2000 Growth Index, which gained 25.71%, due to factor and style headwinds—as high-beta and momentum stocks soared, its lower-volatility, quality-focused holdings underperformed. The Fund continues to prioritize quality businesses, risk management, and downside protection, with portfolio adjustments driven by strategic allocation. In addition, please check the Fund’s top five holdings to know its best picks in 2026. In its Q2 2026 investor letter, Meridian Small Cap Growth Fund highlighted Veracyte, Inc. (NASDAQ:VCYT). Veracyte, Inc. (NASDAQ:VCYT), a global diagnostic company, contributed to the fund's performance during the quarter. On July 29, 2026, Veracyte, Inc. (NASDAQ:VCYT) closed at $55.71 per share, reflecting a market capitalization of $4.44 billion. Veracyte, Inc. (NASDAQ:VCYT) posted a one-month return of -2.40%, while its shares gained 136.96% over the past 52 weeks. Meridian Small Cap Growth Fund stated the following regarding Veracyte, Inc. (NASDAQ:VCYT) in its Q2 2026 investor update: Veracyte, Inc. (NASDAQ:VCYT) is not on our list of 40 Most Popular Stocks Among Hedge Funds Heading Into 2026. According to our database, 32 hedge fund portfolios held Veracyte, Inc. (NASDAQ:VCYT) at the end of the first quarter, up from 28 in the previous quarter. in Q1 2026, Veracyte, Inc. (NASDAQ:VCYT) reported revenue of $139.1 million, representing 21% year-over-year growth. While we acknowledge the potential of Veracyte, Inc. (NASDAQ:VCYT) as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you're looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see our free report on the best short-term AI stock. In addition, please check out our hedge fund investor letters Q2 2026 page for more investor letters from hedge funds and other leading investors. READ NEXT: 33 Stocks That Should Double in 3 Years and 15 Stocks That Will Make You Rich in 10 Years. Disclosure: None. This article is originally published at Insider Monkey.

TranscriptFY2026 Q22026-07-30

FY2026 Q2 earnings call transcript

Earnings source - 100 paragraphs
Operator

Good day, and thank you for standing by. Welcome to the Veracyte Second Quarter 2026 Financial Results Webcast. At this time, all participants are in a listen-only mode. After the speaker's presentation, there will be a question-and-answer session. To ask a question during the session, you will need to press star one one on your telephone. You will hear an automated message advising your hand is raised. To withdraw your question, please press star one one again. Please be advised that today's conference is being recorded. I would now like to hand the conference over to your speaker today, Kelly Gura, Director of Investor Relations. Please go ahead.

Kelly Gura

Good afternoon, everyone, and thank you for joining us today to review Veracyte's second quarter 2026 financial results. Joining me on the call are Marc Stapley, our Chief Executive Officer, and Rebecca Chambers, our Chief Financial Officer. Dr. John Leite, our Chief Commercial Officer, will also be available for Q&A. Earlier this afternoon, we issued a press release detailing our second quarter financial results. We posted an accompanying presentation in the Investors section of our website. Before we begin, I'd like to remind you that statements we make during this call will include forward-looking statements as defined under applicable securities laws. Forward-looking statements are subject to risks and uncertainties. The company can give no assurance that they will prove to be correct. The company undertakes no obligation to update any forward-looking statements except as required by law.

Kelly Gura

To better understand the risks and uncertainties that could cause actual results to differ, we refer you to the documents that Veracyte files with the Securities and Exchange Commission, including the most recent Forms 10-Q and 10-K. This call will include certain non-GAAP financial measures. Reconciliations of these measures to the most directly comparable GAAP financial measures are included in today's earnings release, accessible from the Investors section of Veracyte's website. I will now turn the call over to Marc Stapley, Veracyte's CEO.

Marc Stapley

Thank you, Kelly, and thank you all for joining us today. Q2 was a milestone quarter for Veracyte as we launched Prosigna LDT and TrueMRD, catalyzing two of our key growth opportunities and meaningfully expanding our portfolio. We advanced the clinical evidence supporting Prosigna, Decipher, and Afirma while delivering another quarter of double-digit growth and industry-leading profitability. These achievements reflect years of investment in our platform, the growing body of evidence supporting our tests, and our differentiated commercial capabilities. They enhance our ability to reach and positively impact more patients. Today, our portfolio helps guide patient care across multiple cancer types and increasingly across the cancer care continuum, from risk assessment through recurrence monitoring. As we continue to expand that impact, we are approaching one of the most meaningful milestones in our company's history, serving our one millionth patient.

Marc Stapley

The recent launches of Prosigna LDT and TrueMRD for muscle-invasive bladder cancer, or MIBC, represent the culmination of years of hard work. To say I'm proud of these accomplishments and of our team for delivering them would be an understatement. I want to thank our employees and external collaborators whose expertise and partnership made these outcomes possible. I'm also grateful to the physicians who have worked with us to advance cancer care and to the many thousands of patients whose participation in research helped make these innovations possible. Since launching the Prosigna test in the U.S. following the presentation of the practice-changing OPTIMA trial results at ASCO, we've seen tremendous enthusiasm from both physicians and patients. Prosigna helps guide treatment decisions at a pivotal point in the breast cancer care journey by quantifying the risk of recurrence up to 10 years and providing a likelihood of chemotherapy benefit.

Marc Stapley

Backed by the most rigorous clinical trial demonstration to date, Prosigna achieves this by providing intrinsic subtyping classification information from the well-validated, well-published PAM50 signature that highlights the underlying biology driving the patient's cancer. This helps identify patients who can benefit from chemotherapy and those who may be able to safely avoid it. Prosigna is foundational to our breast cancer franchise and represents one of the most significant product launches in Veracyte's history. As a reminder, OPTIMA is an independent prospective phase III randomized trial that enrolled more than 4,400 high-risk early-stage breast cancer patients. The study met its primary endpoint and demonstrated that more than two-thirds of clinically high-risk patients may safely avoid chemotherapy without compromising outcomes. Importantly, this includes premenopausal women and patients with up to nine positive lymph nodes.

Marc Stapley

The OPTIMA results also generated significant media attention, making OPTIMA and Prosigna the most covered diagnostic story at ASCO. Looking ahead, publication in a leading peer-review journal will represent another important milestone, further validating this level 1A prospective evidence supporting Prosigna and its potential inclusion in future clinical guidelines. We see a significant opportunity to expand access to Prosigna in the U.S., where approximately 225,000 patients are diagnosed with ER-positive, HER2-negative breast cancer each year. We believe many of these patients may benefit from the clinically validated insights Prosigna provides to help inform treatment decisions. With OPTIMA, Prosigna has the only clinically validated evidence for premenopausal women and patients with higher nodal involvement. This expands and strengthens the clinical utility already demonstrated in many prior studies, including as a prognostic test for node-negative patients.

Marc Stapley

There are 157 publications to date featuring Prosigna and more than 1,200 publications featuring the PAM50 classifier on which the test was built. In the near term, we are focused on educating key opinion leaders and driving adoption in high volume centers. While menopausal status and nodal involvement may present the catalyst for the initial conversation, we believe healthcare providers will choose a test they can use with confidence across all ER-positive, HER2-negative patients, rather than stratifying their use based on these differentiating factors alone. We have been thrilled by the quality and breadth of engagement since launch, which gives us confidence our commercial strategy is on point. We are now actively engaged with more than 100 institutions that help shape standards of care in breast cancer, including nationally recognized academic cancer centers, large integrated health systems, and regional oncology networks.

Marc Stapley

Many of these organizations are evaluating broad adoption of Prosigna across their breast cancer programs, and in some cases have expressed interest in using Prosigna for all hormone receptor-positive patients that they treat. Based on this strong engagement, the growing activity on our ordering platform and our customers' desire to start incorporating Prosigna into existing practice management workflows, we are expanding our sales force ahead of our original plan to capture the demand we are seeing. We are making progress on reimbursement and continue to have constructive discussions with MolDX regarding Medicare coverage. We are encouraged by the engagement to date and look forward to providing updates as those discussions progress. I couldn't be more excited about the momentum we have seen since launch.

Marc Stapley

While early, the response from patients, clinicians, key opinion leaders, and the broader oncology community reinforces our conviction that Prosigna can become a meaningful growth driver for Veracyte and even more importantly, improve quality of life for the hundreds of thousands of patients dealing with breast cancer. Turning now to MRD. We launched our first test on our TrueMRD platform in June after securing Medicare reimbursement for recurrence monitoring in patients with MIBC following radical cystectomy. The TrueMRD monitoring test for MIBC represents the first commercial application of our MRD platform and our entry into this rapidly growing market. Importantly, our whole genome approach to MRD is extensible well beyond bladder cancer, with the potential to support multiple tumor types and clinical applications over time.

Marc Stapley

TrueMRD for MIBC is the first and only commercially available MRD test to utilize whole genome sequencing for not just the landmark test, but also through longitudinal monitoring with all subsequent liquid biopsy surveillance tests. We believe this is a meaningful differentiator, offering a broader view of tumor biology and the ability to track tumor evolution over time. Capabilities we expect will become increasingly important as oncology research and testing advances. More broadly, we believe Veracyte is uniquely positioned to serve patients across the bladder cancer continuum. Today, Decipher Bladder helps physicians risk stratify patients, and with TrueMRD for MIBC, we are adding recurrence monitoring at another critical point in the patient journey. Over time, we expect continued evidence generation, product enhancements, and portfolio expansion to further strengthen our position in bladder cancer management.

Marc Stapley

We are leveraging the strong brand we have built through Decipher and our long-standing relationships across urology and radiation oncology to accelerate awareness and adoption of our first TrueMRD test. In parallel, we are investing in the operational infrastructure, workflow enhancements, and automation needed to support larger testing volumes as we intentionally expand the platform over time. While we remain in the early stages of commercialization of TrueMRD for MIBC, we have been encouraged by the initial feedback from physicians who recognize the advantages of a truly whole genome approach and the complementarity to our overall bladder program. We continue to believe that the TrueMRD platform has the potential to become an important long-term growth driver for Veracyte. Moving on to Decipher Prostate.

Marc Stapley

We delivered another strong quarter of revenue growth, up 20% year-over-year, driven primarily by 17% volume growth with improved ASP contributing the balance. ASP growth reflects the significant focused work our market access and billing teams completed over the last year, including operational improvements, strong payer engagement, and expanded coverage across multiple accounts, which led to higher recoveries per test. With just under 30,000 tests resulted in the second quarter, we continued to see strong underlying demand for Decipher. Having said that, we are taking our expectations for volume for the year down by approximately 1% or slightly more than 1,000 tests, primarily in the low-risk setting. Importantly, our expectations for the rest of the business remain on track. Low-risk disease represents an important growth opportunity for Decipher and one where we are also actively investing to generate additional high-quality evidence.

Marc Stapley

The 2025 NCCN guideline update reinforced the need for additional high-quality evidence supporting the use of genomic testing in low-risk patients considering active surveillance. We have a growing clinical data pipeline that we believe will address this unmet need with several prospective and retrospective studies underway evaluating Decipher in active surveillance and low-risk patient populations with initial readouts as early as 2027. As these data emerge, we believe they have the potential to further expand the clinical foundation for Decipher, supporting broader low-risk adoption and guideline inclusion over time. Turning to the balance of the Decipher business, which grew approximately 20% in Q2 2026 off of a challenging prior year comp. Recall that Q2 2025 benefited from the initial step-up in testing following the 2024 NCCN guideline update made late in the year, which reflected Decipher's position as the only gene expression test supported by high-quality evidence.

Marc Stapley

That step up has proved durable and the underlying order trends this quarter give us confidence that the Decipher business is on a consistent trajectory of growth. For example, in Q2, we delivered our highest sequential volume growth since that exceptional quarter last year. This growth was driven by both a strong increase in new ordering physicians and deeper penetration within our existing base. Orders per physician reached a new record, reflecting broader Decipher use by our core physician base across more of their patients. Together, these trends show that physicians are increasingly relying on Decipher to provide critical information that helps guide treatment decisions for patients with prostate cancer across risk groups. We were particularly encouraged by strong ordering trends in intermediate and high-risk localized disease, as well as post-prostatectomy and biochemical recurrence.

Marc Stapley

These remain some of the largest and most attractive growth opportunities for Decipher, reflecting areas where the clinical evidence base is strongest, guideline support is uniquely established, and physician adoption continues to deepen. More broadly, evidence generation remains robust across these settings as well as the metastatic setting, a critical component to ensuring continued adoption and long-term growth. During the quarter, Decipher Prostate was featured in more than 35 publications and abstracts, including Level 1B evidence from the ENZAMET trial presented at ASCO. This study provided new predictive evidence supporting Decipher Prostate to help inform use of Triplet Therapy in metastatic prostate cancer, identifying patients most likely to benefit from the addition of chemotherapy to standard doublet hormone therapy. Looking ahead, we are excited about the steady drumbeat of upcoming conference presentations in the second half of the year.

Marc Stapley

At ASCO in September, Decipher is expected to be featured in six oral presentations, including three focused on treatment intensification with Androgen Deprivation Therapy, or ADT, a key area of clinical decision making in intermediate risk and post-RP Biochemical Recurrent prostate cancer. We are particularly excited about upcoming analyses from NRG RTOG 0815, which we believe have the potential to further establish Decipher's role in personalizing treatment with radiation and ADT for intermediate risk prostate cancer patients, our largest indication. We are also looking forward to results from the SPORT trial, evaluating whether PAM50-based subtyping can provide additional clinically useful information in prostate cancer. Together with additional data expected at ESMO later this year supporting Decipher's utility in high-risk disease, these presentations represent additional data expanding the clinical utility of our tests across the prostate cancer continuum.

Marc Stapley

Beyond prostate cancer, we saw encouraging Q2 order trends for Decipher Bladder, which helps physicians risk stratify patients with muscle invasive as well as non-muscle invasive disease and guide treatment decisions. The test was featured in 13 publications and abstracts in Q2, including six abstracts at AUA and more expected later this year at ESMO, highlighting our growing body of evidence across the bladder cancer continuum. Looking ahead, we remain highly confident in Decipher's long-term growth opportunity, supported by expansion of our customer base, durable and broader physician adoption, an expanding body of clinical and real-world evidence, including multiple important study readouts expected over the next few years, and continued innovation across our platform. Turning now to Afirma. We delivered another strong quarter with approximately 18,600 tests, representing 10% year-over-year volume growth and 18% revenue growth.

Marc Stapley

We were pleased to see another quarter of increased utilization among existing physicians, continued expansion of our ordering physician base, and ongoing market share gains, reinforcing Afirma's position as a market leader in thyroid nodule molecular diagnostics. Revenue growth benefited from both sustained ASP gains and favorable reimbursement wins from commercial payers. We also continue to realize the benefits of our V2 transcriptome workflow, which has improved our no result rate significantly, resulting in more patients receiving a test result and contributing to approximately 400 basis points of volume growth in the quarter. Evidence generation remains a key component of the Afirma growth strategy, as it does for all of our tests. Afirma was featured in 10 conference abstracts during the quarter across leading medical meetings, including American Association of Endocrine Surgeons, American Association of Clinical Endocrinology, and the Endocrine Society.

Marc Stapley

Multiple peer-reviewed manuscripts were published during the quarter and growing interest from independent investigators evaluating Afirma's clinical utility in real-world practice continues to be a competitive differentiation. We are encouraged by the growing momentum behind Afirma GRID, which is supporting an expanding pipeline of academic and industry collaborations. These GRID collaborations fuel a virtuous cycle of expanding evidence, leading to new publications, scientific presentations, and molecular insights that will continue to strengthen the evidence base around Afirma. We expect to see more Afirma publications and scientific abstracts this year than in 2025, further accelerating that momentum. Overall, we remain very pleased with Afirma's performance and believe the combination of continued adoption, share gains, operational improvements, and expanding clinical evidence positions the franchise for continued growth.

Marc Stapley

In closing, seeing years of investment and innovation translate into meaningful new opportunities for growth is incredibly rewarding and a testament to the strength of our strategy, our execution, and most importantly, our people. Our mission remains centered on improving patient outcomes. Today, our portfolio is helping clinicians and patients make more informed treatment decisions across multiple cancer types and increasingly across the cancer care continuum. Supported by the continued strength of our core franchises, a robust pipeline of clinical evidence, and multiple opportunities for future innovation, we remain confident in our ability to continue to deliver durable double-digit growth for the foreseeable future. With that, I'll turn the call over to Rebecca.

Rebecca Chambers

Thanks, Marc. We delivered total revenue of $150.3 million in the second quarter, representing 15% year-over-year growth. Total volume increased to approximately 51,000 tests, up 13% compared to the same period in 2025. We generated $45.8 million of cash from operations, ending the quarter with $485.2 million in cash equivalents, and short-term investments. Testing revenue for the quarter was $145.7 million, an increase of 19% year-over-year, driven by Decipher and Afirma growth of 20% and 18% respectively. Total testing volume was 48,389 tests, representing 14% year-over-year growth. Testing ASP was $3,010, up 4% to the prior year and inclusive of approximately $4.5 million of prior period collections, or PPCs. Excluding PPCs, normalized ASP increased 3% to approximately $2,900, driven by the benefits of operational efforts put into place over the course of 2025, which have led to sustained pricing gains in the first half of this year.

Rebecca Chambers

Turning to gross margin and operating expenses, I'll focus on our non-GAAP results. Non-GAAP gross margin was 74.9%, up 340 basis points year-over-year, driven by strength in our testing business. Testing gross margin increased 200 basis points to 76%, reflecting operational efficiencies from our V2 transcriptome workflow, higher ASP, and PPCs. Non-GAAP operating expenses increased 16% year-over-year to $70 million. As we shared last quarter, certain IT expenses associated with software development and project management resources previously reported in G&A have been moved directly into R&D as they are fully dedicated to our product development objectives. As a result, R&D expense increased $12.1 million year-over-year to $26.3 million, approximately half of which were driven by our organizational changes and the other half driven by increased clinical and product investments.

Rebecca Chambers

Sales and marketing expense increased $2.4 million to $25.5 million, reflecting hiring to support our existing portfolio, as well as the recent launches of Prosigna LDT and TrueMRD. G&A expense decreased $4.8 million to $18.1 million, primarily due to the organizational changes previously mentioned. From a profitability standpoint, we delivered GAAP net income of $25.5 million in the quarter. Adjusted EBITDA was $44 million, or 29.2% of revenue, up 23% year-over-year and above our long-term target of 25%. This level of profitability continues to demonstrate our operating leverage as we both invest in our growth drivers and generate meaningful cash. Turning to our 2026 outlook, we are raising full-year total revenue guidance to $590 million-$596 million, representing 14% to 15% year-over-year growth compared to our prior range of $582 million-$592 million.

Rebecca Chambers

This reflects expected testing revenue of $576 million-$582 million, representing 17% to 18% year-over-year growth, compared to our prior range of $570 million-$580 million, with testing volume growth modestly below revenue. Included in our guidance is approximately $10 million of other testing revenue from cytology services and Decipher Bladder. Further, our guidance assumes approximately 20% Decipher revenue growth. Based on current ordering trends and normal seasonality, we expect approximately 31,000 tests in Q3 and 33,000 in Q4. Given PPCs collected year to date and stronger than expected ASP performance this year, we now expect ASP to be slightly higher this year compared to 2025. For Afirma, we have increased our revenue guidance to approximately 12% to 14% year-over-year growth, driven by favorable year-to-date PPCs, ongoing ASP improvement, and an anticipated no result rate of benefit of approximately 3% for the year.

Rebecca Chambers

Due to typical seasonality and in line with prior years, we expect Q3 volume to be slightly down sequentially, with a larger step-up in Q4. On revenue, Afirma is expected to step down sequentially, given close to $3 million of PPCs in the second quarter. As Marc shared, we are pleased with the early feedback on our recently launched tests. Given we do not yet have Medicare reimbursement for Prosigna and are still early in the launch process, our revenue guidance excludes contribution from these tests. Moving to profitability, we are maintaining our full year Adjusted EBITDA guidance of greater than 26%, reflecting our expected investment to support our growth initiatives throughout the year. As always, while we plan expenses on an annual basis, Adjusted EBITDA may fluctuate quarter to quarter. In closing, Q2 was a milestone quarter for Veracyte.

Rebecca Chambers

We successfully launched two important new products that expand our ability to serve patients across the cancer care continuum, while also delivering strong double-digit revenue growth, profitability, and cash generation. Combined with the strength of our core business, these achievements reinforce our confidence in our long-term growth opportunity and position us well to continue to deliver durable double-digit growth. We will now move into the Q&A portion of the call. Operator, please open the lines.

Operator

As a reminder, to ask a question, please press star one one on your telephone and wait for your name to be announced. To withdraw your question, please press star one one again. In the interest of time, we ask that you please limit yourself to one question and one follow. Please stand by while we compile the Q&A roster. Our first question comes from Tycho Peterson with Jefferies. Your line is open.

Speaker 4

Hey, team. This is Lauren on for Tycho. Thanks so much for taking the question. My first one would be on Decipher. With the lowered guidance about 1K tests, are you seeing a threat, specifically from AI-based testing? Off that topic, if these approaches continue to improve, what do you see as the future workflow? Would it be an AI-first triage model followed by molecular confirmation, or are there certain indications where molecular profiling will remain the gold standard? Thanks.

Marc Stapley

Hi, Lauren. Thanks for the question. No, we're not actually. The reduction in our internal expectations for Decipher for the year is only in the low category, where we took it down by about 1,000 tests. Most of which is actually behind us in the second quarter. We think the rationale for that and what we're seeing there is the guideline change that happened at the end of last year, where effectively for every test, whether molecular or AI-based, for active surveillance, it was taken out of guidelines. So it's going to depend on for that to come back and grow in double digits. It's still growing in single digits for us, but for it to come back and grow in double digits, it's going to need the evidence that we talked about.

Marc Stapley

We had slightly higher expectations for that coming into the year than we currently do in low risk only. That affects every test on the market in similar ways. Not everybody has the same comp. In fact, low was very good for us in this quarter last year. I'm sure, for others, they have different starting points. From a share standpoint, we're not really seeing any difference at all. I think to the second part of your question, it doesn't really feature when that's not the fact here. We still think that molecular and AI are complementary. We already know they measure different parts of the biology and different things and we've got a publication that we're working on that covers that we've talked about previously.

Marc Stapley

I think the two could potentially coexist at some point, but I don't think it's necessarily a one or the other model. In fact, physicians consistently tell us more information is better than less. Anything to add? No.

Rebecca Chambers

I'll just add one quick thing, if you don't mind. That really is to highlight the strength that we saw in the intermediate and high-risk category, as well as the durability of that strength, given incremental data that we hope will be released here shortly, as Marc mentioned on the call. Yes, we have taken down the low category by a day or two across the portion of the year. I think we are seeing great strength and performance as expected in intermediate and high. Those are the areas where we have the most evidence, we have the most guidelines and that will change here for low as well over the course of 2027, 2028, 2029.

Rebecca Chambers

I think, to me, the way I think about it is we have a great growth driver today, low is an opportunity for incremental growth in the subsequent years and is a very untapped market at this point in time.

Marc Stapley

Lauren, maybe if I can, sorry, just to add to what Rebecca said. While we expect these low publication or studies to read out in 2027, 2028, we don't know if they're going to read out positively or not. The good news is we have multiple shots on goal with multiple studies coming our way.

Rebecca Chambers

That have been enrolling now for six, seven years. Exciting times.

Speaker 4

That's super helpful. Thank you. Just one last one on expansion of the market for Prosigna. I guess, what percent of the existing Oncotype market do you think is contestable over the next three to five years? What do you expect the earliest uptake in, whether it's across the node-positive populations or just color there? Thanks.

John Leite

This is John. Thanks for the question. Yeah, we're not limiting ourselves to any specific subsegments of the breast market. We believe the entirety of the HER2-negative, ER-positive population is addressable by our value proposition. The latest data from OPTIMA happens to add predictive claims to the node-positive population, both post-menopausal and pre-menopausal. The large value proposition here always starts with an accurate risk stratification to understand what is the real risk of progression in the 10-year timeframe. For that, we already have Level 1A evidence across the board. Like I said, we're excited by the OPTIMA results, but we're not limiting ourselves to just that node-positive population.

Rebecca Chambers

Maybe one last thing to add. We haven't gone out and quantified what portion of the market we think we can take over the next three to five years, I would say, as Marc stated in the script, based on some early feedback, we are very confident in our ability to have sustained growth with Prosigna and have had numerous conversations with centers that are large in nature who are contemplating not just dabbling and having more active engagement and to the point of effectively fully switching. We are optimistic, and our optimism is fueled by engagement with the market post the OPTIMA results.

Speaker 4

Thanks so much, guys, and congrats again on the quarter.

Rebecca Chambers

Thanks, Lauren.

Operator

Thank you. Our next question comes from Subbu Nambi with Guggenheim. Your line is open.

Speaker 6

Hi, this is Ricki on for Subu. Thanks for taking our question. For a little more color maybe on just how you're thinking about Prosigna going forward from more of a commercial lens. In our early KOL checks, oncologists have been really optimistic about adopting Prosigna and really excited about it, EMR integration and ordering end results through the EMR were really the one headwind that's been mentioned in terms of increasing adoption. Could you speak to your plans for that type of integration or any other commercial or logistic initiatives you're focused on to support more Prosigna adoption? Thank you.

John Leite

Thanks for the question. We can't disagree. We believe that at volume, EHR integration goes a long way, not just to simplify the logistical burden on the practice administrators and the physicians, but also in just streamlining and even potentially automating some of the test ordering and automation into the overall workflow. Having said all that, we are heavily investing in our team here that's able to leverage both internal resources and external partners and external service providers to get us integrated with as many practices as possible. The good news here is that was already an activity that was on its way to support our Decipher and Afirma business, and that we can tag team on those efforts. Absolutely can't agree anymore.

Operator

Thank you. Our next question comes from Keith Hinton with Freedom Capital Markets. Your line is open.

Keith Hinton

Great, thanks. Just one quick one on Decipher and then a question on guidance. On Decipher, can you just talk a little bit about the low-risk population, what kind of the penetration level is today for molecular diagnostics, and with the guideline changes that you're hoping to have reversed in the future with additional data, where you think that penetration rate could go over the next few years?

Marc Stapley

Happy to. I can talk about our penetration. We think we're about 20% penetrated into this important low-risk market. In fact, the penetration is growing every quarter. Even in this quarter, we saw a growth in the number of new customers and a growth in the number of ordering customers. It's continuing to grow at a rate that, we said single-digit, that exceeds the rate of incidence growth. For it to really kick into a new gear, we do think it will need that NCCN guideline. Between now and then, I think it's going to continue to penetrate more as it grows every quarter, hopefully every quarter and certainly every year. I think guidelines put it in the same category as intermediate and now what we're seeing with high-risk.

Rebecca Chambers

That is, to be clear, our expectation is that we believe that we can have at least 80% penetration and a similar amount of share, if not more, on a sustainable basis at optimized penetration. There's a huge runway, not only in the low-risk opportunity but equally in the high and to a lesser extent, intermediate, though there's still immense amount of white space left in intermediate. You want to move on to the Decipher question, Keith? I'm sorry, the guidance question?

Operator

Thank you. Our next question comes from Jakob Dodd with Morgan Stanley. Your line is now open.

Speaker 8

Hi, good evening. Thanks, Aman, for Dodd tonight. Correct me if I'm wrong, but I believe Prosigna launched with commercial coverage, but not with MolDX. Could you help us understand how you're managing patient access for Medicare beneficiaries right now? Are you performing those tests at risk? What is your current expectation for the MolDX timeline and confidence level based on OPTIMA data? Thank you.

John Leite

Yeah. Prosigna has already enjoyed coverage from Medicare via our on-market FDA-approved product. Our plan had been to transition away from the FDA distributed product towards a centralized LDT. From a coverage perspective, we're covered. The process moving forward is to submit a tech assessment that outlines our lab validation, the analytical validation, our bridging study to the FDA-approved product and platform, and to have that reviewed and subsequently approved by Medicare. We've already been enjoying a few exchanges with MolDX. We see the path forward as fairly straightforward and kind of see the approval of that tech assessment imminently. The last step would then be an agreement of pricing, and for that, we have multiple paths to a secure price, and we've guided before to expect the low end of that pricing around $2,500.

Speaker 8

Great. Thanks.

Operator

Thank you. Our next question comes from Keith Hinton with Freedom Capital Markets. Your line is open.

Keith Hinton

Great. Thanks for taking the follow-up. Just quickly on guidance, obviously the results in the first two quarters of the year have been meaningfully above that 26% floor that you guys have given, which you maintained. I just want to ask how much of that is the incremental investment you talked about pulling forward some of the sales force build for Prosigna and how much of it is just conservatism or however you want to think about it and if you can give any color to the level of investment that you're pulling forward for Prosigna as well?

Rebecca Chambers

Yeah. I'll handle that last part first. We are going from a roughly 10-person sales force exiting this year to a 15-person sales force as of this year. That's not going to be a material, that meaningful of a contribution. As John spoke about, obviously EMRs are part of our activity plan here, and that is something that we are investing in, and we'll invest as much as we can because that is such a high ROI endeavor. All that being said, I wouldn't call this conservatism, Keith. I would call it two things. One, we have a huge opportunity in front of us with a deep pipeline across multiple indications, across multiple portions of the care continuum that we want to invest in to drive higher revenue growth in the future, even above and beyond the relatively attractive levels we are today.

Rebecca Chambers

I think we have a great opportunity in front of us across MRD, Decipher, Afirma, the rest of the urology space, and obviously Prosigna. We're investing heavily in there. I would say the other thing on our guide is we don't necessarily guide on a go-forward basis with PPCs, and PPCs have been a significant contributor to the outperformance year to date. That is just something to take into account. We don't guide that in revenue. We don't guide it in profitability. The last thing I would say on gross margin, we've had amazing gross margin performance as we do see significant Prosigna volume in the back half of the year, given our revenue recognition policies as well as just the lack of reimbursement from the get-go. That is going to be a slight headwind, and that would be something to take into account.

Rebecca Chambers

If you want to call that Prosigna investment, feel free. Those are really the contributing factors.

Keith Hinton

Great. Thank you very much.

Operator

Thank you. Our next question comes from Puneet Souda with Leerink Partners. Your line is open.

Puneet Souda

Hi, guys. Thanks for the questions here. Just on Decipher, just wondering, Decipher low risk, do you believe there was any impact from the ACA disenrollment on the volumes? Was this all largely comp issues that you saw in the quarter? How should we think about overall growth for Decipher? You pointed out a number of drivers that helped in 2024 NCCN and it's been a very strong product. How should we think about sort of the stable growth trajectory? What is that number for Decipher? I'm wondering if you can provide anything for 2027 color if you would like to. Thank you.

Marc Stapley

Thanks, Puneet. It's a combination of, I think, the comp and what we're seeing in the low risk, which is, as I mentioned, is kind of more of a single-digit grower than not a double-digit grower right now based on what we're seeing. Still growing, but not at the same level as the rest of the Decipher risk categories, obviously, given those guidelines for NCCN. Yeah, we expect that to continue, and that's why we adjusted our outlook by about 1,000 tests. We also have very strong performance on the revenue line for Decipher as well. We've maintained Decipher around 20% revenue growth for the year, which is very healthy.

Marc Stapley

We are extremely excited about the high risk and intermediate that are both growing very nicely given our competitive advantages in NCCN guidelines there and the raft of evidence that we have supporting Decipher's use for clinical decisions in those two contexts. When I say high risk, of course, that includes BCR and metastatic, which is a relatively new area for us as well. When you put it all together, those parts are growing nicely. To your question on the kind of go-forward trajectory, Decipher is on this very straight line. I think I've mentioned it before. When you look at it's got a very high R squared, and what's happening there is highly predictable in that regard. I don't see any reason why that kind of trend line should change in the next couple of years.

Marc Stapley

It seems to be around 20,000 tests a year, plus or minus 1,000 or so. That's the variability that I would put on that. Like I said, I don't see much coming that would change that other than in that timeframe we talked about. Hopefully, we get the evidence to get low risk to be in a very similar category.

Rebecca Chambers

Maybe just one thing while I have the opportunity to add on the Afirma number for next year. I just would like everyone to remember that we have the benefit of the NRR in our 2026 results and our 2026 guide. That will create a harder comp next year on Afirma. Also Afirma PPCs have been quite outstanding year to date. Just please take those two things into account when you're looking at your 2027 numbers for Afirma.

Puneet Souda

Got it. That's helpful. When we think about Prosigna, there's a premenopausal node-positive position that could benefit patients that could benefit. Could you elaborate sort of what the discussions have been so far? How is the traction in the market just since the launch? How should we think about any volume numbers this year or next year for Prosigna?

John Leite

Well, from a market response, I'd say the market responded very favorably to the release of the OPTIMA trial data. Obviously, premenopausal and high node burden in general is what caused probably the larger splash effect because it is so game-changing. Nevertheless, as I've been saying, we believe that our overall opportunity covers the gamut of the HER2-negative, ER-positive population. Nevertheless, that's why I imagine, Puneet, those physicians are going to start and then expand from there if it ends up being a land and expand strategy with some physicians, and quite a few of them, I believe that will be the case. Others we've had discussions with are ready to pull the trigger wholesale because it's just easier to deal with one provider. The conversation turns very quickly from clinical to logistical. With regards to numbers, we're not quite there to guide with targets.

John Leite

We're going to allow ourselves the opportunity to collect data over the next coming months, before we can guide with some accuracy.

Marc Stapley

Puneet, just to remind everybody, I mentioned that there are hundreds of publications that support Prosigna's use in node-negative population as well. To John's point, I think it's both the ease and also the level of evidence and the robustness behind Prosigna and the PAM50 signature that is also appealing.

Puneet Souda

Got it. Okay. Just last clarification, I might have missed this, but the Decipher growth was more than 20%, and it's now going to be at 20% held constant. Just wanted to clarify on that point for this year guide.

Marc Stapley

Yeah, to be clear, that's the revenue. The revenue guide is at 20%, and we gave very specific numbers for Q3 and Q4 for volume. Now, of course, don't forget, there's always this quarterly volume variability that can come from the timing of receiving orders and tissue coming in the door and results being reported out. You should always expect that level of a day's worth of variability, give or take. Remember, given how much we've grown now in Decipher, a day's volume is 500 tests or so. It's very significant running through our lab every single day. You should expect the normal level of fluctuation on the quarterly numbers. We always say focus on the year. Overall, we're guiding roughly 20% growth for Decipher revenue growth for the year.

Rebecca Chambers

Puneet, the ASP gains that we've gotten are making up for the 1,000 test delta in the volume guide.

Puneet Souda

Got it. Okay. Thank you.

Rebecca Chambers

There are prior periods in the back half of last year as a comp to take into account on pricing. Just we can go through that later today if you want.

Puneet Souda

I see. Okay. All right. Helpful. All right, thanks.

Marc Stapley

Thanks, Puneet.

Operator

Thank you. Our next question comes from Mason Carrico with Stephens. Your line is open.

Mason Carrico

Hey, guys. Jumping between a few tonight, so sorry if this has been asked. I'll just keep it to one here. Could you update us on the TrueMRD pipeline? When should we expect to see the next data readout? When will we learn more about the next submission to MolDX or indication that you'll be targeting there?

Marc Stapley

Yeah. Thanks, Mason. No, that hasn't been asked. Focusing on TrueMRD, obviously we're very happy with the launch of our first test in muscle invasive bladder cancer. As we've always talked about, that's kind of our landmark test, if you like, that helps us pilot our MRD approach in a relatively small but very important indication. That's where we're focused right now. Meantime, we do have our development teams and our clinical teams working on the next levels of evidence development and the next assays, and so on. We'll talk more about that when we're ready to launch those tests. We had a review just this week on the various studies that are going on and when they're expected to read out in different indications. It's good. There's a lot of things happening, and hopefully, we'll add to that over the next few years as well.

Marc Stapley

Excited for the bladder test to prove the proof point here and then expand on that.

Mason Carrico

Got it. Thank you.

Marc Stapley

Thank you.

Operator

Thank you. Our next question comes from Kyle Mikson with Canaccord Genuity. Your line is open.

Alex DeCaso

Hi, this is Alex DeCaso in the line for Kyle Mikson. Thank you for taking our questions. Apologies if any of these are repeats. I've been on a few different calls today. Prosigna NGS became available for order June 8th, and it's covered by a significant number of commercial payers in the past. Can you just comment on early test adoption? Do you believe that the OPTIMA study results could be the key to guideline inclusion or either future or true test volume inflection? Thank you.

John Leite

Yeah. I'll take that one at a time. With regards to adoption, yes, we're very pleased with both the reaction that we've gotten from physicians, I would say even unexpectedly from patients who've reached out to us directly asking how they can get the test. Having seen now the first few results going back, it's just been very emotional and very gratifying to be able to start to help this important pool of patients. I think it absolutely signifies that we will see healthy adoption. We're very happy with the early KPIs, like I said, with the response as well. There's always a bit of a lag in terms of setting up accounts and our logistical systems and ensuring that we are clear through their procurement offices. We're happy with where we're tracking this soon after the launch.

John Leite

As it relates to the OPTIMA trial, yes, we believe that it is generally acknowledged as Level 1A evidence, should make its way to guidelines. What stands in our way between now and then is a publication. As we've communicated in the past, that's out of our hands. This is an independent study run by a group of PIs. We'll keep you posted as we make progress and as the guidelines review the data.

Operator

Thank you. As a reminder, to ask a question, please press star one one on your telephone. Again, that is star one one to ask a question. Our next question comes from David Westenberg with Piper Sandler. Your line is open.

Speaker 12

Hey, guys. This is Bron on for David Westenberg. I've been jumping around as well. I'll keep it brief. Apologies if this has been asked. Maybe sticking with the pipeline, can you give us an update on the NIGHTINGALE study? I think previously you mentioned roughly 90% enrolled. When could we expect to hear maybe intermediate data? That'd be appreciated. Thank you.

Marc Stapley

Yeah, happy to. No, it hasn't been asked. The NIGHTINGALE study, just to remind everybody, it's a very extensive study that we have done on Percepta nasal swab test. It was completed in enrollment last August, I believe it was. We're about a year in now. Well, almost a year into having those first patient follow-ups. It's going to be a while before that fully reads out. We're treating that as one of our longer-term growth drivers. That's where we are on Nightingale. Looking forward to seeing how that reads out once we've got all the patients followed for at least one year, if not potentially two.

Operator

Thank you. Our next question comes from Joseph Conway with Needham & Company. Your line is open.

Joseph Conway

Hey, everyone. Thanks for taking our questions. Maybe one on Decipher to start out with. Really strong quarter. Just wondering maybe how much of the growth in the quarter, if you could dissect it, is maybe from expansion into new use cases or newer use cases, whether it be treatment intensification or the metastatic setting versus maybe just higher overall penetration in the use cases that you guys have had for the last handful of years. Maybe just in the same vein, looking forward, which of those buckets do you think will be more repeatable over the next couple of years, whether it be new indications or continued market penetration in existing?

Marc Stapley

Yeah, I think the best way to actually think about it is the risk categories that we've been discussing Decipher in. Within each of those risk categories, more evidence comes out that adds either more prognostic or predictive claims. A good example of that is in high risk and metastatic, where you've seen evidence come out at ESMO for STAMPEDE at ASCO for ENZAMET, which keep adding these predictive claims and is one of the factors that is helping to grow the high risk and metastatic category, which is one of the higher growth driver categories within Decipher. Intermediate continues to be an absolute stalwart of growth in terms of adding new. We're constantly adding new customers who have not ordered Decipher before.

Marc Stapley

We're seeing a nice uptick in the ordering rate per customer, which means they're expanding it across their patient population, even within an intermediate risk category, for example. Other than low risk, which again, just to remind people, low risk is growing in terms of we're adding new customers for low risk, but it's not growing at the double-digit rate. It's more of a single-digit rate now. I think if you think about it like that, the growth in the next couple of years is going to come from high risk and intermediate, and then the growth after that is going to come from low risk when we have the active surveillance evidence supporting that in guidance.

Rebecca Chambers

The other thing outside of the prostate portion of the urology market for Decipher, obviously, we're quite excited about the opportunity for bladder. It's just starting to get going, but the data evidence generation engine has been fully at work here now for a couple of years. We are incrementally excited about the bladder opportunity in the back half of the decade as well.

Joseph Conway

Back half. Okay, great. Just one more. I know you guys get this question a decent amount, but just in terms of share buybacks or M&A, obviously you have a couple of launches and pipeline projects that are prioritizing a lot of investment now. Is there maybe a specific cash balance or profitability metric where you guys start thinking about buybacks more, or maybe it's more about waiting until the launches and the pipeline is more in the rear view? I'm just wondering how you guys are thinking about that, if it's more of a dollar metric or more of a milestone kind of thing.

Marc Stapley

Yeah. No, not really. I wouldn't say it was that scientific. It's really, we look at the capital deployment in really three categories. One is continued investment in our business, Rebecca ran through earlier some of the things that we're doing there to really help drive the launch of these two new products. Our pipeline of additional new products and innovations, and also the core growth in Decipher and Afirma. That's priority number one, is invest in the business and continue to make it grow as we have done year after year after year. The second is, you've mentioned it, but M&A. We've done a few acquisitions as a company, and we do look at the market and we look at a lot of different things, and we're very open to the right assets being a part of Veracyte at the right time.

Marc Stapley

The third category would be returning to investors in the way that you've described. That to me at this point, when you think of all these other two categories and the things we got ahead of us and the opportunities for us to deploy capital, is not top of mind, but we regularly look at that and discuss it. You can rest assured it's certainly on the docket. It's just we've got plenty of things going on right now.

Joseph Conway

Thanks, everyone, for taking our questions, and congrats on a very strong quarter.

Marc Stapley

Thank you.

Rebecca Chambers

Thank you. Have a great afternoon.

Operator

Thank you. This concludes the question and answer session and today's conference call. Thank you for participating. You may now disconnect.

Investor releaseQuarter not tagged2026-07-28

Analysts Estimate TransMedics (TMDX) to Report a Decline in Earnings: What to Look Out for

Zacks
TransMedics (TMDX) is expected to deliver a year-over-year decline in earnings on higher revenues when it reports results for the quarter ended June 2026. This widely-known consensus outlook gives a good sense of the company's earnings picture, but how the actual results compare to these estimates is a powerful factor that could impact its near-term stock price. The stock might move higher if these key numbers top expectations in the upcoming earnings report, which is expected to be released on August 4. On the other hand, if they miss, the stock may move lower. While the sustainability of the immediate price change and future earnings expectations will mostly depend on management's discussion of business conditions on the earnings call, it's worth handicapping the probability of a positive EPS surprise. This medical technology company is expected to post quarterly earnings of $0.50 per share in its upcoming report, which represents a year-over-year change of -45.7%. Revenues are expected to be $184.17 million, up 17% from the year-ago quarter. The consensus EPS estimate for the quarter has been revised 2.85% lower over the last 30 days to the current level. This is essentially a reflection of how the covering analysts have collectively reassessed their initial estimates over this period. Investors should keep in mind that an aggregate change may not always reflect the direction of estimate revisions by each of the covering analysts. Price, Consensus and EPS Surprise Estimate revisions ahead of a company's earnings release offer clues to the business conditions for the period whose results are coming out. This insight is at the core of our proprietary surprise prediction model -- the Zacks Earnings ESP (Expected Surprise Prediction). The Zacks Earnings ESP compares the Most Accurate Estimate to the Zacks Consensus Estimate for the quarter; the Most Accurate Estimate is a more recent version of the Zacks Consensus EPS estimate. The idea here is that analysts revising their estimates right before an earnings release have the latest information, which could potentially be more accurate than what they and others contributing to the consensus had predicted earlier. Thus, a positive or negative Earnings ESP reading theoretically indicates the likely deviation of the actual earnings from the consensus estimate. However, the model's predictive power is significant f…Read full document

TransMedics (TMDX) is expected to deliver a year-over-year decline in earnings on higher revenues when it reports results for the quarter ended June 2026. This widely-known consensus outlook gives a good sense of the company's earnings picture, but how the actual results compare to these estimates is a powerful factor that could impact its near-term stock price. The stock might move higher if these key numbers top expectations in the upcoming earnings report, which is expected to be released on August 4. On the other hand, if they miss, the stock may move lower. While the sustainability of the immediate price change and future earnings expectations will mostly depend on management's discussion of business conditions on the earnings call, it's worth handicapping the probability of a positive EPS surprise. This medical technology company is expected to post quarterly earnings of $0.50 per share in its upcoming report, which represents a year-over-year change of -45.7%. Revenues are expected to be $184.17 million, up 17% from the year-ago quarter. The consensus EPS estimate for the quarter has been revised 2.85% lower over the last 30 days to the current level. This is essentially a reflection of how the covering analysts have collectively reassessed their initial estimates over this period. Investors should keep in mind that an aggregate change may not always reflect the direction of estimate revisions by each of the covering analysts. Price, Consensus and EPS Surprise Estimate revisions ahead of a company's earnings release offer clues to the business conditions for the period whose results are coming out. This insight is at the core of our proprietary surprise prediction model -- the Zacks Earnings ESP (Expected Surprise Prediction). The Zacks Earnings ESP compares the Most Accurate Estimate to the Zacks Consensus Estimate for the quarter; the Most Accurate Estimate is a more recent version of the Zacks Consensus EPS estimate. The idea here is that analysts revising their estimates right before an earnings release have the latest information, which could potentially be more accurate than what they and others contributing to the consensus had predicted earlier. Thus, a positive or negative Earnings ESP reading theoretically indicates the likely deviation of the actual earnings from the consensus estimate. However, the model's predictive power is significant for positive ESP readings only. A positive Earnings ESP is a strong predictor of an earnings beat, particularly when combined with a Zacks Rank #1 (Strong Buy), 2 (Buy) or 3 (Hold). Our research shows that stocks with this combination produce a positive surprise nearly 70% of the time, and a solid Zacks Rank actually increases the predictive power of Earnings ESP. Please note that a negative Earnings ESP reading is not indicative of an earnings miss. Our research shows that it is difficult to predict an earnings beat with any degree of confidence for stocks with negative Earnings ESP readings and/or Zacks Rank of 4 (Sell) or 5 (Strong Sell). For TransMedics, the Most Accurate Estimate is higher than the Zacks Consensus Estimate, suggesting that analysts have recently become bullish on the company's earnings prospects. This has resulted in an Earnings ESP of +8.87%. On the other hand, the stock currently carries a Zacks Rank of #5. So, this combination makes it difficult to conclusively predict that TransMedics will beat the consensus EPS estimate. While calculating estimates for a company's future earnings, analysts often consider to what extent it has been able to match past consensus estimates. So, it's worth taking a look at the surprise history for gauging its influence on the upcoming number. For the last reported quarter, it was expected that TransMedics would post earnings of $0.62 per share when it actually produced earnings of $0.30, delivering a surprise of -51.61%. Over the last four quarters, the company has beaten consensus EPS estimates three times. An earnings beat or miss may not be the sole basis for a stock moving higher or lower. Many stocks end up losing ground despite an earnings beat due to other factors that disappoint investors. Similarly, unforeseen catalysts help a number of stocks gain despite an earnings miss. That said, betting on stocks that are expected to beat earnings expectations does increase the odds of success. This is why it's worth checking a company's Earnings ESP and Zacks Rank ahead of its quarterly release. Make sure to utilize our Earnings ESP Filter to uncover the best stocks to buy or sell before they've reported. TransMedics doesn't appear a compelling earnings-beat candidate. However, investors should pay attention to other factors too for betting on this stock or staying away from it ahead of its earnings release. Among the stocks in the Zacks Medical - Instruments industry, Veracyte (VCYT), is soon expected to post earnings of $0.43 per share for the quarter ended June 2026. This estimate indicates a year-over-year change of -2.3%. This quarter's revenue is expected to be $144.36 million, up 10.9% from the year-ago quarter. The consensus EPS estimate for Veracyte has remained unchanged over the last 30 days. However, a lower Most Accurate Estimate has resulted in an Earnings ESP of -1.16%. This Earnings ESP, combined with its Zacks Rank #4 (Sell), makes it difficult to conclusively predict that Veracyte will beat the consensus EPS estimate. The company beat consensus EPS estimates in each of the trailing four quarters. Stay on top of upcoming earnings announcements with the Zacks Earnings Calendar. Want the latest recommendations from Zacks Investment Research? Today, you can download 7 Best Stocks for the Next 30 Days. Click to get this free report TransMedics Group, Inc. (TMDX) : Free Stock Analysis Report Veracyte, Inc. (VCYT) : Free Stock Analysis Report This article originally published on Zacks Investment Research (zacks.com). Zacks Investment Research

Investor releaseQuarter not tagged2026-07-23

Earnings Preview: Veracyte (VCYT) Q2 Earnings Expected to Decline

Zacks
The market expects Veracyte (VCYT) to deliver a year-over-year decline in earnings on higher revenues when it reports results for the quarter ended June 2026. This widely-known consensus outlook is important in assessing the company's earnings picture, but a powerful factor that might influence its near-term stock price is how the actual results compare to these estimates. The earnings report, which is expected to be released on July 30, might help the stock move higher if these key numbers are better than expectations. On the other hand, if they miss, the stock may move lower. While management's discussion of business conditions on the earnings call will mostly determine the sustainability of the immediate price change and future earnings expectations, it's worth having a handicapping insight into the odds of a positive EPS surprise. This molecular diagnostic company is expected to post quarterly earnings of $0.43 per share in its upcoming report, which represents a year-over-year change of -2.3%. Revenues are expected to be $144.36 million, up 10.9% from the year-ago quarter. The consensus EPS estimate for the quarter has remained unchanged over the last 30 days. This is essentially a reflection of how the covering analysts have collectively reassessed their initial estimates over this period. Investors should keep in mind that the direction of estimate revisions by each of the covering analysts may not always get reflected in the aggregate change. Price, Consensus and EPS Surprise Estimate revisions ahead of a company's earnings release offer clues to the business conditions for the period whose results are coming out. Our proprietary surprise prediction model -- the Zacks Earnings ESP (Expected Surprise Prediction) -- has this insight at its core. The Zacks Earnings ESP compares the Most Accurate Estimate to the Zacks Consensus Estimate for the quarter; the Most Accurate Estimate is a more recent version of the Zacks Consensus EPS estimate. The idea here is that analysts revising their estimates right before an earnings release have the latest information, which could potentially be more accurate than what they and others contributing to the consensus had predicted earlier. Thus, a positive or negative Earnings ESP reading theoretically indicates the likely deviation of the actual earnings from the consensus estimate. However, the model's predictive powe…Read full document

The market expects Veracyte (VCYT) to deliver a year-over-year decline in earnings on higher revenues when it reports results for the quarter ended June 2026. This widely-known consensus outlook is important in assessing the company's earnings picture, but a powerful factor that might influence its near-term stock price is how the actual results compare to these estimates. The earnings report, which is expected to be released on July 30, might help the stock move higher if these key numbers are better than expectations. On the other hand, if they miss, the stock may move lower. While management's discussion of business conditions on the earnings call will mostly determine the sustainability of the immediate price change and future earnings expectations, it's worth having a handicapping insight into the odds of a positive EPS surprise. This molecular diagnostic company is expected to post quarterly earnings of $0.43 per share in its upcoming report, which represents a year-over-year change of -2.3%. Revenues are expected to be $144.36 million, up 10.9% from the year-ago quarter. The consensus EPS estimate for the quarter has remained unchanged over the last 30 days. This is essentially a reflection of how the covering analysts have collectively reassessed their initial estimates over this period. Investors should keep in mind that the direction of estimate revisions by each of the covering analysts may not always get reflected in the aggregate change. Price, Consensus and EPS Surprise Estimate revisions ahead of a company's earnings release offer clues to the business conditions for the period whose results are coming out. Our proprietary surprise prediction model -- the Zacks Earnings ESP (Expected Surprise Prediction) -- has this insight at its core. The Zacks Earnings ESP compares the Most Accurate Estimate to the Zacks Consensus Estimate for the quarter; the Most Accurate Estimate is a more recent version of the Zacks Consensus EPS estimate. The idea here is that analysts revising their estimates right before an earnings release have the latest information, which could potentially be more accurate than what they and others contributing to the consensus had predicted earlier. Thus, a positive or negative Earnings ESP reading theoretically indicates the likely deviation of the actual earnings from the consensus estimate. However, the model's predictive power is significant for positive ESP readings only. A positive Earnings ESP is a strong predictor of an earnings beat, particularly when combined with a Zacks Rank #1 (Strong Buy), 2 (Buy) or 3 (Hold). Our research shows that stocks with this combination produce a positive surprise nearly 70% of the time, and a solid Zacks Rank actually increases the predictive power of Earnings ESP. Please note that a negative Earnings ESP reading is not indicative of an earnings miss. Our research shows that it is difficult to predict an earnings beat with any degree of confidence for stocks with negative Earnings ESP readings and/or Zacks Rank of 4 (Sell) or 5 (Strong Sell). For Veracyte, the Most Accurate Estimate is lower than the Zacks Consensus Estimate, suggesting that analysts have recently become bearish on the company's earnings prospects. This has resulted in an Earnings ESP of -1.16%. On the other hand, the stock currently carries a Zacks Rank of #4. So, this combination makes it difficult to conclusively predict that Veracyte will beat the consensus EPS estimate. Analysts often consider to what extent a company has been able to match consensus estimates in the past while calculating their estimates for its future earnings. So, it's worth taking a look at the surprise history for gauging its influence on the upcoming number. For the last reported quarter, it was expected that Veracyte would post earnings of $0.34 per share when it actually produced earnings of $0.52, delivering a surprise of +52.94%. Over the last four quarters, the company has beaten consensus EPS estimates four times. An earnings beat or miss may not be the sole basis for a stock moving higher or lower. Many stocks end up losing ground despite an earnings beat due to other factors that disappoint investors. Similarly, unforeseen catalysts help a number of stocks gain despite an earnings miss. That said, betting on stocks that are expected to beat earnings expectations does increase the odds of success. This is why it's worth checking a company's Earnings ESP and Zacks Rank ahead of its quarterly release. Make sure to utilize our Earnings ESP Filter to uncover the best stocks to buy or sell before they've reported. Veracyte doesn't appear a compelling earnings-beat candidate. However, investors should pay attention to other factors too for betting on this stock or staying away from it ahead of its earnings release. IQVIA Holdings (IQV), another stock in the Zacks Medical - Instruments industry, is expected to report earnings per share of $3.02 for the quarter ended June 2026. This estimate points to a year-over-year change of +7.5%. Revenues for the quarter are expected to be $4.3 billion, up 7% from the year-ago quarter. Over the last 30 days, the consensus EPS estimate for IQVIA has been revised 0.5% down to the current level. Nevertheless, the company now has an Earnings ESP of -2.98%, reflecting a lower Most Accurate Estimate. This Earnings ESP, combined with its Zacks Rank #3 (Hold), makes it difficult to conclusively predict that IQVIA will beat the consensus EPS estimate. The company beat consensus EPS estimates in each of the trailing four quarters. Stay on top of upcoming earnings announcements with the Zacks Earnings Calendar. Want the latest recommendations from Zacks Investment Research? Today, you can download 7 Best Stocks for the Next 30 Days. Click to get this free report Veracyte, Inc. (VCYT) : Free Stock Analysis Report IQVIA Holdings Inc. (IQV) : Free Stock Analysis Report This article originally published on Zacks Investment Research (zacks.com). Zacks Investment Research

Investor releaseQuarter not tagged2026-07-09

Veracyte to Release Second Quarter 2026 Financial Results on July 30, 2026

Business Wire

SOUTH SAN FRANCISCO, Calif., July 09, 2026--(BUSINESS WIRE)--Veracyte, Inc. (Nasdaq: VCYT), a leading cancer diagnostics company, announced today that it will release financial results for the second quarter 2026 after the close of market on Thursday, July 30, 2026. Company management will host a conference call and webcast to discuss financial results and provide a general business update at 4:30 p.m. Eastern Time on the same day. The conference call will be webcast live from the company’s website and will be available via the following link: https://edge.media-server.com/mmc/p/wwu2pyd7. A webcast replay will be available following the conclusion of the live broadcast and will be accessible on the company’s website at https://investor.veracyte.com/events-presentations. About Veracyte Veracyte (Nasdaq: VCYT) is a global diagnostics company with a vision to transform cancer care for patients around the world. The company’s molecular tests assess the unique biology of each patient’s tumor to help clinicians answer essential questions about cancer care. Veracyte’s Diagnostics Platform combines broad genomic and clinical data, advanced bioinformatics and AI, and a powerful evidence-generation engine to support continued innovation and pipeline development. The company’s portfolio includes the Afirma® Genomic Sequencing Classifier test, Decipher® Bladder Genomic Classifier test, Decipher® Prostate Genomic Classifier test, Prosigna® Breast Risk of Recurrence test, and the TrueMRD™ Monitoring Test for MIBC. For more information, visit Veracyte’s website or follow the company on LinkedIn or X (Twitter). View source version on businesswire.com: https://www.businesswire.com/news/home/20260709945913/en/ Contacts Investors Kelly [email protected] Media Molly [email protected] +1-650-351-8780

Investor releaseQuarter not tagged2026-06-04

Why Is Veracyte (VCYT) Up 18.2% Since Last Earnings Report?

Zacks
A month has gone by since the last earnings report for Veracyte (VCYT). Shares have added about 18.2% in that time frame, outperforming the S&P 500. Will the recent positive trend continue leading up to its next earnings release, or is Veracyte due for a pullback? Before we dive into how investors and analysts have reacted as of late, let's take a quick look at the latest earnings report in order to get a better handle on the important drivers. Veracyte, Inc. (VCYT) delivered first-quarter 2026 adjusted earnings of 52 cents per share, up 67.7% from the year-ago period. The bottom line beat the Zacks Consensus Estimate by 52.9%. The company’s GAAP earnings per share were 35 cents compared with the year-ago period’s 9 cents per share. Revenues increased 21.5% year over year to $ 139.1 million, which outpaced the Zacks Consensus Estimate by 6.6%. Veracyte raised its 2026 total revenue guidance to $582-$592 million or 13-14% growth (up from $570-$582 million or 10-13%). The Zacks Consensus Estimate for revenues is currently pegged at $580.3 million, implying 12.2% year-over-year growth. Additionally, Veracyte raised its adjusted EBITDA margin guidance to greater than 26%, up from its prior expectation of approximately 25%. It turns out, estimates review flatlined during the past month. At this time, Veracyte has a great Growth Score of A, though it is lagging a lot on the Momentum Score front with a C. Charting a somewhat similar path, the stock has a grade of D on the value side, putting it in the bottom 40% for value investors. Overall, the stock has an aggregate VGM Score of B. If you aren't focused on one strategy, this score is the one you should be interested in. Veracyte has a Zacks Rank #3 (Hold). We expect an in-line return from the stock in the next few months. Veracyte belongs to the Zacks Medical - Instruments industry. Another stock from the same industry, Edwards Lifesciences (EW), has gained 3.4% over the past month. More than a month has passed since the company reported results for the quarter ended March 2026. Edwards Lifesciences reported revenues of $1.65 billion in the last reported quarter, representing a year-over-year change of +16.7%. EPS of $0.78 for the same period compares with $0.64 a year ago. For the current quarter, Edwards Lifesciences is expected to post earnings of $0.73 per share, indicating a change of +9% from the year-ago q…Read full document

A month has gone by since the last earnings report for Veracyte (VCYT). Shares have added about 18.2% in that time frame, outperforming the S&P 500. Will the recent positive trend continue leading up to its next earnings release, or is Veracyte due for a pullback? Before we dive into how investors and analysts have reacted as of late, let's take a quick look at the latest earnings report in order to get a better handle on the important drivers. Veracyte, Inc. (VCYT) delivered first-quarter 2026 adjusted earnings of 52 cents per share, up 67.7% from the year-ago period. The bottom line beat the Zacks Consensus Estimate by 52.9%. The company’s GAAP earnings per share were 35 cents compared with the year-ago period’s 9 cents per share. Revenues increased 21.5% year over year to $ 139.1 million, which outpaced the Zacks Consensus Estimate by 6.6%. Veracyte raised its 2026 total revenue guidance to $582-$592 million or 13-14% growth (up from $570-$582 million or 10-13%). The Zacks Consensus Estimate for revenues is currently pegged at $580.3 million, implying 12.2% year-over-year growth. Additionally, Veracyte raised its adjusted EBITDA margin guidance to greater than 26%, up from its prior expectation of approximately 25%. It turns out, estimates review flatlined during the past month. At this time, Veracyte has a great Growth Score of A, though it is lagging a lot on the Momentum Score front with a C. Charting a somewhat similar path, the stock has a grade of D on the value side, putting it in the bottom 40% for value investors. Overall, the stock has an aggregate VGM Score of B. If you aren't focused on one strategy, this score is the one you should be interested in. Veracyte has a Zacks Rank #3 (Hold). We expect an in-line return from the stock in the next few months. Veracyte belongs to the Zacks Medical - Instruments industry. Another stock from the same industry, Edwards Lifesciences (EW), has gained 3.4% over the past month. More than a month has passed since the company reported results for the quarter ended March 2026. Edwards Lifesciences reported revenues of $1.65 billion in the last reported quarter, representing a year-over-year change of +16.7%. EPS of $0.78 for the same period compares with $0.64 a year ago. For the current quarter, Edwards Lifesciences is expected to post earnings of $0.73 per share, indicating a change of +9% from the year-ago quarter. The Zacks Consensus Estimate remained unchanged over the last 30 days. The overall direction and magnitude of estimate revisions translate into a Zacks Rank #3 (Hold) for Edwards Lifesciences. Also, the stock has a VGM Score of D. Want the latest recommendations from Zacks Investment Research? Today, you can download 7 Best Stocks for the Next 30 Days. Click to get this free report Veracyte, Inc. (VCYT) : Free Stock Analysis Report Edwards Lifesciences Corporation (EW) : Free Stock Analysis Report This article originally published on Zacks Investment Research (zacks.com). Zacks Investment Research

As of 2026-08-01 • Updated weeklySource: Earnings sourceIngestion runbook