B+
Bull case
25%
Probability
Target price
$50.00
Analysis reference price unavailable
Analysis 2026-07-25 · RankAlpha Sentiment Codex
SEPN
SepternaDNasdaq / Pharmaceuticals, Biotechnology & Life Sciences
Last Price
Quote time unavailable
Current thesis
Septerna has constructive pipeline momentum: SEP-631 Phase 1 results support Phase 2b development, SEP-479 has entered Phase 1, and the reported cash runway reduces near-term financing risk [#SEC-8K-2026-05-11].
Posture
Defensive
Lead driver
Value
What changed
Value remains the lead driver in the composite, 7D delta -0.3.
What can break
Clinical trial execution, tolerability, enrollment, and readout risk across SEP-631 and SEP-479.
Momentum
84
Value
51
Sentiment
42
Setup hits (3d)
0 · Net Neutral
AI TargetsBase $36.00 · Bull $50.00 · Bear $24.00Analysis 2026-07-25; returns require an exact persisted reference.
Data freshness
Prices
Unavailable: Price unavailable
Fundamentals
As of 2026-10-26 • Vendor: Data Vendor v1
Scores
As of 2026-10-26 • Model: HYBRID_IC_RP
AI Memo
As of 2026-07-25 • Model: RankAlpha Sentiment Codex
Investment thesisAs of 2026-10-26
Investment thesis
As of 2026-10-26
Grade is the composite factor band; factor scores use a 0–100 scale. Confidence describes evidence quality, not a probability of return. Score date: 2026-10-26. Definitions
Supporting evidence
What
Grade D · Defensive
Confidence Medium · Net Neutral
Target $54.22
Why
Momentum84 · Δ7d +11.6
Value51 · Δ7d -0.3
Sentiment42 · Δ7d -12.6
So what
Weak posture (Net Neutral). Prioritize risk control and patience.
Confirming evidence
- • Value remains the lead driver in the composite, 7D delta -0.3.
Contradictions & invalidation
- • Clinical trial execution, tolerability, enrollment, and readout risk across SEP-631 and SEP-479.
- • Continued cash burn could eventually require financing and dilution despite the stated runway.
- • The thesis remains clinical and execution-dependent.
Catalyst clock
2026-10-23
SEP-479 Phase 1 data
Lead driver: Value · See fundamentals
Momentum
84
8% active weight
Current posture
7d trendImproving
Δ7d
+11.6
Δ21d
+2.0
Value
51
47% active weight
Current posture
7d trendFlat
Δ7d
-0.3
Δ21d
-0.5
Sentiment
42
45% active weight
Current posture
7d trendSoftening
Δ7d
-12.6
Δ21d
-15.4
Why this grade
Composite grade D. Momentum 83.7 / Value 51.1 / Sentiment 42.5
Scenario snapshot
Scenario probability is memo-authored likelihood, not forecast certainty. Targets belong to the analysis dated 2026-07-25. Scenario method
Most likely
B
Base case
50%
Probability
Target price
$36.00
Analysis reference price unavailable
Analysis 2026-07-25 · RankAlpha Sentiment Codex
B-
Bear case
25%
Probability
Target price
$24.00
Analysis reference price unavailable
Analysis 2026-07-25 · RankAlpha Sentiment Codex
Fundamentals (TTM)As of 2026-10-26
Fundamentals (TTM)
As of 2026-10-26
Market Cap
$1.93B
Beta
-
Shares Out
46.68M
P/E (TTM) · Derived
-37.5
P/S (TTM)
-
P/FCF (TTM) · Derived
18.15
Rev YoY
+22375.6%
EPS YoY
-48.5%
Gross Margin
+98.3%
Op Margin
-56.7%
Net Debt
-$367.46M
Current Ratio
4.99
As of 2026-10-26 • Updated nightlySource: Internal modelMethods & Data