B+
Bull case
25%
Probability
Target price
$50.00
Analysis reference price unavailable
Analysis 2026-07-25 · RankAlpha Sentiment Codex
SEPN
SepternaCNasdaq / Pharmaceuticals, Biotechnology & Life Sciences
Last Price
Quote time unavailable
Current thesis
Septerna has constructive pipeline momentum: SEP-631 Phase 1 results support Phase 2b development, SEP-479 has entered Phase 1, and the reported cash runway reduces near-term financing risk [#SEC-8K-2026-05-11].
Posture
Mixed
Lead driver
Sentiment
What changed
Sentiment remains the lead driver in the composite, 7D delta +6.9.
What can break
Clinical trial execution, tolerability, enrollment, and readout risk across SEP-631 and SEP-479.
Momentum
79
Value
52
Sentiment
59
Setup hits (3d)
0 · Net Neutral
AI TargetsBase $36.00 · Bull $50.00 · Bear $24.00Analysis 2026-07-25; returns require an exact persisted reference.
Data freshness
Prices
Unavailable: Price unavailable
Fundamentals
As of 2026-08-17 • Vendor: Data Vendor v1
Scores
As of 2026-09-09 • Model: HYBRID_IC_RP
AI Memo
As of 2026-07-25 • Model: RankAlpha Sentiment Codex
Investment thesisAs of 2026-09-09
Investment thesis
As of 2026-09-09
Grade is the composite factor band; factor scores use a 0–100 scale. Confidence describes evidence quality, not a probability of return. Score date: 2026-09-09. Definitions
Supporting evidence
What
Grade C · Mixed
Confidence Medium · Net Neutral
Target $54.22
Why
Momentum79 · Δ7d -0.8
Value52 · Δ7d 0.0
Sentiment59 · Δ7d +6.9
So what
Balanced signals (Net Neutral). Wait for confirmation before sizing up.
Confirming evidence
- • Sentiment remains the lead driver in the composite, 7D delta +6.9.
Contradictions & invalidation
- • Clinical trial execution, tolerability, enrollment, and readout risk across SEP-631 and SEP-479.
- • Continued cash burn could eventually require financing and dilution despite the stated runway.
- • The thesis remains clinical and execution-dependent.
Catalyst clock
2026-10-23
SEP-479 Phase 1 data
Lead driver: Sentiment · See AI snapshot
Momentum
79
9% active weight
Current posture
7d trendImproving
Δ7d
-0.8
Δ21d
-13.9
Value
52
28% active weight
Current posture
7d trendFlat
Δ7d
0.0
Δ21d
-5.3
Sentiment
59
62% active weight
Current posture
7d trendImproving
Δ7d
+6.9
Δ21d
+20.4
Why this grade
Composite grade C. Momentum 79.2 / Value 51.7 / Sentiment 58.8
Scenario snapshot
Scenario probability is memo-authored likelihood, not forecast certainty. Targets belong to the analysis dated 2026-07-25. Scenario method
Most likely
B
Base case
50%
Probability
Target price
$36.00
Analysis reference price unavailable
Analysis 2026-07-25 · RankAlpha Sentiment Codex
B-
Bear case
25%
Probability
Target price
$24.00
Analysis reference price unavailable
Analysis 2026-07-25 · RankAlpha Sentiment Codex
Fundamentals (TTM)As of 2026-08-17
Fundamentals (TTM)
As of 2026-08-17
Market Cap
$2.06B
Beta
-
Shares Out
46.68M
P/E (TTM) · Derived
-40.0
P/S (TTM)
-
P/FCF (TTM) · Derived
19.39
Rev YoY
+22375.6%
EPS YoY
-48.5%
Gross Margin
+98.3%
Op Margin
-56.7%
Net Debt
-$367.46M
Current Ratio
4.99
As of 2026-09-09 • Updated nightlySource: Internal modelMethods & Data