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Earnings documents stored for PACB.
Investor releaseQuarter not tagged2026-09-08Q2 Earnings Highlights: PacBio (NASDAQ:PACB) Vs The Rest Of The Life Sciences Tools & Services Stocks
StockStory
Q2 Earnings Highlights: PacBio (NASDAQ:PACB) Vs The Rest Of The Life Sciences Tools & Services Stocks
Quarterly earnings results are a good time to check in on a company’s progress, especially compared to its peers in the same sector. Today we are looking at PacBio (NASDAQ:PACB) and the best and worst performers in the life sciences tools & services industry. The life sciences tools and services sector supports biotech and pharmaceutical R&D and commercialization by providing lab equipment, data analytics, and clinical trial services. These companies benefit from recurring revenue and high margins on specialized products. Looking ahead, the sector is supported by tailwinds like advancements in genomics, personalized medicine, and the use of AI in drug discovery. However, the persistent challenge is dependence on the R&D budgets of large pharmaceutical companies and the volatility of smaller biotech firms. Future headwinds include uncertain research funding and pricing pressures from cost-conscious customers. The 21 life sciences tools & services stocks we track reported a strong Q2. As a group, revenues beat analysts’ consensus estimates by 2.6% while next quarter’s revenue guidance was 0.5% above. Thankfully, share prices of the companies have been resilient as they are up 8.9% on average since the latest earnings results. Pioneering what scientists call "HiFi long-read sequencing," recognized as Nature Methods' method of the year for 2022, Pacific Biosciences (NASDAQ:PACB) develops advanced DNA sequencing systems that enable scientists and researchers to analyze genomes with unprecedented accuracy and completeness. PacBio reported revenues of $39.01 million, down 1.9% year on year. This print fell short of analysts’ expectations by 2.3%. Overall, it was a disappointing quarter for the company with a significant miss of analysts’ EPS estimates. PacBio delivered the weakest performance against analyst estimates of the whole group. Interestingly, the stock is up 3.6% since reporting and currently trades at $1.35. Read our full report on PacBio here, it’s free. Serving as the guardian of some of medicine's most valuable materials, Azenta (NASDAQ:AZTA) provides biological sample management, storage, and genomic services that help pharmaceutical and biotechnology companies preserve and analyze critical research materials. Azenta reported revenues of $161.2 million, up 12% year on year, outperforming analysts’ expectations by 8%. The business had an incredible qu…Read full documentShow less
Quarterly earnings results are a good time to check in on a company’s progress, especially compared to its peers in the same sector. Today we are looking at PacBio (NASDAQ:PACB) and the best and worst performers in the life sciences tools & services industry. The life sciences tools and services sector supports biotech and pharmaceutical R&D and commercialization by providing lab equipment, data analytics, and clinical trial services. These companies benefit from recurring revenue and high margins on specialized products. Looking ahead, the sector is supported by tailwinds like advancements in genomics, personalized medicine, and the use of AI in drug discovery. However, the persistent challenge is dependence on the R&D budgets of large pharmaceutical companies and the volatility of smaller biotech firms. Future headwinds include uncertain research funding and pricing pressures from cost-conscious customers. The 21 life sciences tools & services stocks we track reported a strong Q2. As a group, revenues beat analysts’ consensus estimates by 2.6% while next quarter’s revenue guidance was 0.5% above. Thankfully, share prices of the companies have been resilient as they are up 8.9% on average since the latest earnings results. Pioneering what scientists call "HiFi long-read sequencing," recognized as Nature Methods' method of the year for 2022, Pacific Biosciences (NASDAQ:PACB) develops advanced DNA sequencing systems that enable scientists and researchers to analyze genomes with unprecedented accuracy and completeness. PacBio reported revenues of $39.01 million, down 1.9% year on year. This print fell short of analysts’ expectations by 2.3%. Overall, it was a disappointing quarter for the company with a significant miss of analysts’ EPS estimates. PacBio delivered the weakest performance against analyst estimates of the whole group. Interestingly, the stock is up 3.6% since reporting and currently trades at $1.35. Read our full report on PacBio here, it’s free. Serving as the guardian of some of medicine's most valuable materials, Azenta (NASDAQ:AZTA) provides biological sample management, storage, and genomic services that help pharmaceutical and biotechnology companies preserve and analyze critical research materials. Azenta reported revenues of $161.2 million, up 12% year on year, outperforming analysts’ expectations by 8%. The business had an incredible quarter with a beat of analysts’ EPS estimates. The market seems content with the results as the stock is up 4% since reporting. It currently trades at $31.33. Is now the time to buy Azenta? Access our full analysis of the earnings results here, it’s free. With roots dating back to the pioneering days of nuclear magnetic resonance technology, Bruker (NASDAQ:BRKR) develops and manufactures high-performance scientific instruments that enable researchers and industrial analysts to explore materials at microscopic, molecular, and cellular levels. Bruker reported revenues of $838.5 million, up 5.2% year on year, falling short of analysts’ expectations by 1.9%. It was a slower quarter as it posted a slight miss of analysts’ organic revenue estimates and full-year revenue guidance slightly missing analysts’ expectations. Bruker delivered the weakest full-year guidance update among its peers. As expected, the stock is down 9% since the results and currently trades at $58.50. Read our full analysis of Bruker’s results here. Formerly known as PerkinElmer until its rebranding in 2023, Revvity (NYSE:RVTY) provides health science technologies and services that support the complete workflow from discovery to development and diagnosis to cure. Revvity reported revenues of $711.1 million, up 4.5% year on year. This result surpassed analysts’ expectations by 0.6%. Overall, it was a strong quarter as it also produced a beat of analysts’ EPS estimates and an impressive beat of analysts’ full-year EPS guidance estimates. The stock is up 12.8% since reporting and currently trades at $130. Read our full, actionable report on Revvity here, it’s free. Originally spun off from Hewlett-Packard in 1999 as its measurement and analytical division, Agilent Technologies (NYSE:A) provides analytical instruments, software, services, and consumables for laboratory workflows in life sciences, diagnostics, and applied chemical markets. Agilent reported revenues of $1.88 billion, up 8.1% year on year. This number topped analysts’ expectations by 1.9%. It was a strong quarter as it also recorded an impressive beat of analysts’ organic revenue estimates and a solid beat of analysts’ full-year EPS guidance estimates. Agilent achieved the highest guidance raise in the group. The stock is down 1.6% since reporting and currently trades at $152.53. Read our full, actionable report on Agilent here, it’s free. Over the past year, investors have been forced to repeatedly answer the same question: what is the market’s biggest risk? The answer has changed several times, and each shift has reshaped market leadership. Late in 2025 and early 2026, artificial intelligence became the market’s primary uncertainty. Investors questioned whether AI would erode software pricing power and weaken competitive moats as AI made it easier to replicate once-differentiated products. By the spring, technology took a back seat to geopolitics. The U.S. conflict with Iran briefly became the market’s dominant narrative, raising concerns about oil prices, inflation, and global growth. But as energy markets remained orderly and fears of a prolonged supply disruption faded, investors quickly turned their focus back to fundamentals. Want to invest in winners with rock-solid fundamentals? Check out our Top 5 Growth Stocks and add them to your watchlist. These companies are poised for growth regardless of the political or macroeconomic climate.
Investor releaseQuarter not tagged2026-09-04Pacific Biosciences (PACB) Up 11.6% Since Last Earnings Report: Can It Continue?
Zacks
Pacific Biosciences (PACB) Up 11.6% Since Last Earnings Report: Can It Continue?
A month has gone by since the last earnings report for Pacific Biosciences of California (PACB). Shares have added about 11.6% in that time frame, outperforming the S&P 500. But investors have to be wondering, will the recent positive trend continue leading up to its next earnings release, or is Pacific Biosciences due for a pullback? Well, first let's take a quick look at its most recent earnings report in order to get a better handle on the recent catalysts for Pacific Biosciences of California, Inc. before we dive into how investors and analysts have reacted as of late. PacBio reported an adjusted loss per share of 14 cents for the second quarter of 2026, wider than the year-ago adjusted loss of 13 cents per share. The figure came in line with the Zacks Consensus Estimate. The company’s GAAP loss per share was 14 cents in the quarter, flat year over year. PacBio registered total revenues of $39 million, down 2% year over year. The figure missed the Zacks Consensus Estimate by 4.2%. Consumables growth and higher Revio placements were offset by weaker instrument sales and a sharp revenue decline in Asia Pacific. Americas revenues were $17.6 million, down 0.6% year over year. Continued uncertainty surrounding NIH, academic and government funding weighed on capital purchasing, though clinical and commercial customer activity remained resilient. Asia-Pacific revenues totaled $7 million, down 45% year over year. The decrease reflected the completion of a significant population-sequencing program, weaker academic and government demand and lower consumables purchases as customers prepared for the SPRQ-Nx transition. EMEA revenues increased 52% year over year to $14.4 million. Growth was driven by clinical customers moving from pilot programs into routine production, stronger Vega demand and a strategic multi-system Revio placement supporting a national genomics initiative. In the quarter under review, total Product revenues amounted to $32.9 million, down 0.4% from the year-ago quarter. Within the Product segment, Instrument revenues were $12.8 million, down 9.9% year over year. The decline reflected a lower average selling price, including strategic Revio placements at key accounts, and fewer Vega shipments amid academic and government funding constraints. Instrument revenues in the quarter included 20 Revio sequencing systems and 26 Vega sequencing systems. PAC…Read full documentShow less
A month has gone by since the last earnings report for Pacific Biosciences of California (PACB). Shares have added about 11.6% in that time frame, outperforming the S&P 500. But investors have to be wondering, will the recent positive trend continue leading up to its next earnings release, or is Pacific Biosciences due for a pullback? Well, first let's take a quick look at its most recent earnings report in order to get a better handle on the recent catalysts for Pacific Biosciences of California, Inc. before we dive into how investors and analysts have reacted as of late. PacBio reported an adjusted loss per share of 14 cents for the second quarter of 2026, wider than the year-ago adjusted loss of 13 cents per share. The figure came in line with the Zacks Consensus Estimate. The company’s GAAP loss per share was 14 cents in the quarter, flat year over year. PacBio registered total revenues of $39 million, down 2% year over year. The figure missed the Zacks Consensus Estimate by 4.2%. Consumables growth and higher Revio placements were offset by weaker instrument sales and a sharp revenue decline in Asia Pacific. Americas revenues were $17.6 million, down 0.6% year over year. Continued uncertainty surrounding NIH, academic and government funding weighed on capital purchasing, though clinical and commercial customer activity remained resilient. Asia-Pacific revenues totaled $7 million, down 45% year over year. The decrease reflected the completion of a significant population-sequencing program, weaker academic and government demand and lower consumables purchases as customers prepared for the SPRQ-Nx transition. EMEA revenues increased 52% year over year to $14.4 million. Growth was driven by clinical customers moving from pilot programs into routine production, stronger Vega demand and a strategic multi-system Revio placement supporting a national genomics initiative. In the quarter under review, total Product revenues amounted to $32.9 million, down 0.4% from the year-ago quarter. Within the Product segment, Instrument revenues were $12.8 million, down 9.9% year over year. The decline reflected a lower average selling price, including strategic Revio placements at key accounts, and fewer Vega shipments amid academic and government funding constraints. Instrument revenues in the quarter included 20 Revio sequencing systems and 26 Vega sequencing systems. PACB ended the quarter with 366 cumulative Revio system shipments and 200 cumulative Vega system shipments. Consumables revenues for the quarter were $20.1 million, up 6.3% from the prior-year quarter, supported by installed-base expansion and continued Revio utilization. Shipments to clinical customers increased 67% and represented a mid-teens percentage of total consumables shipments. Annualized Revio pull-through per system was approximately $202,000 in the quarter. Growth was partly tempered by customers using existing inventory and validating workflows ahead of broader SPRQ-Nx adoption. Service and other revenues totaled $6.1 million, down 9.4% year over year. In the quarter under review, PacBio’s adjusted gross profit decreased 8.3% year over year to $13.9 million. The adjusted gross margin contracted 200 basis points to 36%. Sales, general and administrative expenses declined 7.7% year over year to $33.4 million. Research and development expenses increased 2.2% year over year to $23 million. Adjusted total operating expenses of $56.1 million decreased 3.4% year over year. Total operating loss was $44.6 million in the reported quarter compared with the prior-year quarter’s $44.9 million. PacBio exited the second quarter of 2026 with cash and investments of $236.9 million compared with $275.9 million at the end of the first quarter of 2026. PacBio reduced its 2026 revenue guidance to $155-$165 million from the prior range of $165-$175 million. The Zacks Consensus Estimate is pegged at $165.8 million. The company now expects an adjusted gross margin of 35%-37%. Adjusted operating expenses are projected at $215-$220 million, down $5 million from the previous guidance range. In the past month, investors have witnessed a downward trend in fresh estimates. The consensus estimate has shifted -8.33% due to these changes. Currently, Pacific Biosciences has a subpar Growth Score of D, however its Momentum Score is doing a lot better with a B. However, the stock has a score of F on the value side, putting it in the lowest quintile for this investment strategy. Overall, the stock has an aggregate VGM Score of F. If you aren't focused on one strategy, this score is the one you should be interested in. Estimates have been broadly trending downward for the stock, and the magnitude of this revision indicates a downward shift. It's no surprise Pacific Biosciences has a Zacks Rank #4 (Sell). We expect a below average return from the stock in the next few months. Pacific Biosciences belongs to the Zacks Medical - Instruments industry. Another stock from the same industry, Edwards Lifesciences (EW), has gained 0.5% over the past month. More than a month has passed since the company reported results for the quarter ended June 2026. Edwards Lifesciences reported revenues of $1.74 billion in the last reported quarter, representing a year-over-year change of +13.6%. EPS of $0.78 for the same period compares with $0.67 a year ago. For the current quarter, Edwards Lifesciences is expected to post earnings of $0.73 per share, indicating a change of +9% from the year-ago quarter. The Zacks Consensus Estimate remained unchanged over the last 30 days. The overall direction and magnitude of estimate revisions translate into a Zacks Rank #3 (Hold) for Edwards Lifesciences. Also, the stock has a VGM Score of C. Want the latest recommendations from Zacks Investment Research? Today, you can download 7 Best Stocks for the Next 30 Days. Click to get this free report Pacific Biosciences of California, Inc. (PACB) : Free Stock Analysis Report Edwards Lifesciences Corporation (EW) : Free Stock Analysis Report This article originally published on Zacks Investment Research (zacks.com). Zacks Investment Research
Investor releaseQuarter not tagged2026-08-145 Must-Read Analyst Questions From PacBio’s Q2 Earnings Call
StockStory
5 Must-Read Analyst Questions From PacBio’s Q2 Earnings Call
PacBio’s second quarter was met with a negative market reaction, as sales and adjusted earnings per share both fell short of Wall Street’s expectations. Management attributed the underperformance to ongoing funding constraints in the U.S. academic and government sectors, as well as a transition period as customers validated the new SPRQ-Nx chemistry. CEO Mark Van Oene, newly appointed after Christian Henry’s departure, stated that “customer enthusiasm for SPRQ-Nx has remained strong since full launch,” but acknowledged that the pace of adoption and inventory dynamics weighed on quarterly results. Is now the time to buy PACB? Find out in our full research report (it’s free). Revenue: $39.01 million vs analyst estimates of $39.91 million (1.9% year-on-year decline, 2.3% miss) Adjusted EPS: -$0.14 vs analyst expectations of -$0.13 (10.4% miss) Operating Margin: -114%, down from -113% in the same quarter last year Market Capitalization: $354.3 million While we enjoy listening to the management’s commentary, our favorite part of earnings calls is the analyst questions. Those are unscripted and can often highlight topics that management teams would rather avoid or topics where the answer is complicated. Here is what has caught our attention. Kyle Mikson (Canaccord Genuity) asked whether most new Revio and Vega system placements were to clinical customers. CEO Mark Van Oene explained that the majority were clinical accounts, highlighting ongoing momentum in clinical adoption for both instruments. Thomas VonDerVellen (Guggenheim) inquired about expected consumables pull-through for the second half as population-scale and clinical customers ramp. Van Oene detailed that consumables revenue would likely remain flat in the next quarter, with growth expected as SPRQ-Nx adoption accelerates later in the year. Jack Meehan (Operon Research) questioned gross margin headwinds related to memory supply and when improvements from multi-use SMRT Cells would be realized. CFO James Gibson clarified that memory costs will persist into 2027, with margin benefits from SPRQ-Nx expected to ramp as adoption increases. Mason Carrico (Stephens) asked if the SPRQ-Nx cost reduction would lead to higher sample volumes to offset lower pricing. Van Oene responded that customer demand and project scale should close the revenue gap as adoption ramps in the back half of the year. Lauren Timmins (J…Read full documentShow less
PacBio’s second quarter was met with a negative market reaction, as sales and adjusted earnings per share both fell short of Wall Street’s expectations. Management attributed the underperformance to ongoing funding constraints in the U.S. academic and government sectors, as well as a transition period as customers validated the new SPRQ-Nx chemistry. CEO Mark Van Oene, newly appointed after Christian Henry’s departure, stated that “customer enthusiasm for SPRQ-Nx has remained strong since full launch,” but acknowledged that the pace of adoption and inventory dynamics weighed on quarterly results. Is now the time to buy PACB? Find out in our full research report (it’s free). Revenue: $39.01 million vs analyst estimates of $39.91 million (1.9% year-on-year decline, 2.3% miss) Adjusted EPS: -$0.14 vs analyst expectations of -$0.13 (10.4% miss) Operating Margin: -114%, down from -113% in the same quarter last year Market Capitalization: $354.3 million While we enjoy listening to the management’s commentary, our favorite part of earnings calls is the analyst questions. Those are unscripted and can often highlight topics that management teams would rather avoid or topics where the answer is complicated. Here is what has caught our attention. Kyle Mikson (Canaccord Genuity) asked whether most new Revio and Vega system placements were to clinical customers. CEO Mark Van Oene explained that the majority were clinical accounts, highlighting ongoing momentum in clinical adoption for both instruments. Thomas VonDerVellen (Guggenheim) inquired about expected consumables pull-through for the second half as population-scale and clinical customers ramp. Van Oene detailed that consumables revenue would likely remain flat in the next quarter, with growth expected as SPRQ-Nx adoption accelerates later in the year. Jack Meehan (Operon Research) questioned gross margin headwinds related to memory supply and when improvements from multi-use SMRT Cells would be realized. CFO James Gibson clarified that memory costs will persist into 2027, with margin benefits from SPRQ-Nx expected to ramp as adoption increases. Mason Carrico (Stephens) asked if the SPRQ-Nx cost reduction would lead to higher sample volumes to offset lower pricing. Van Oene responded that customer demand and project scale should close the revenue gap as adoption ramps in the back half of the year. Lauren Timmins (Jefferies) probed why full-year guidance was lowered despite positive SPRQ-Nx signals. Van Oene explained that ongoing transition headwinds and elevated compute costs warranted a more cautious outlook. In coming quarters, the StockStory team will closely monitor (1) the pace of SPRQ-Nx adoption and its impact on consumables growth, (2) progress in clinical and population-scale project expansion, particularly in EMEA and new customer segments, and (3) the company’s success in mitigating supply chain and manufacturing cost pressures. Operational execution in driving clinical engagement and expanding gross margins will also be key signposts for PacBio’s path forward. PacBio currently trades at $1.16, down from $1.30 just before the earnings. At this price, is it a buy or sell? Find out in our full research report (it’s free for active Edge members). ALSO WORTH WATCHING: Top 5 Momentum Stocks. The best time to own a great stock is when the market is finally noticing it. These aren’t just high-quality businesses. Something is happening with them right now. Elite fundamentals meet near-term momentum — both boxes checked at the same time. Find out which stocks our AI platform is flagging this week. See this week’s Strong Momentum stocks — FREE. Get Our Strong Momentum Stocks for Free HERE. Stocks that have made our list include now familiar names such as Nvidia (+1,460% between June 2020 and June 2025) as well as under-the-radar businesses like the once-micro-cap company Tecnoglass (+1,552% between June 2020 and June 2025). Find your next big winner with StockStory today.
Investor releaseQuarter not tagged2026-08-06Pacific Biosciences of California Q2 Earnings Call Highlights
MarketBeat
Pacific Biosciences of California Q2 Earnings Call Highlights
Interested in Pacific Biosciences of California, Inc.? Here are five stocks we like better. Leadership and outlook changed: CEO Christian Henry stepped down and was replaced immediately by Mark Van Oene. PacBio lowered its 2026 revenue forecast to $155 million–$165 million and pushed expected cash-flow breakeven to 2028. Q2 revenue was essentially flat at $39 million: Consumables revenue grew 6% to $20.1 million, but instrument revenue fell 9% to $12.8 million amid fewer Vega shipments and a lower average selling price. SMRT Next adoption is central to the growth strategy: The new multi-use chemistry lowers the cost of a 20x HiFi human genome by 30%, but customer validation and existing reagent inventories are delaying the expected consumables ramp until late 2026. Deciphering Disruption: Inside Cathie Wood's Latest Plays Pacific Biosciences of California (NASDAQ:PACB) reported second-quarter 2026 revenue of $39 million, roughly flat from $39.8 million a year earlier, while announcing an immediate leadership transition and lowering its full-year revenue outlook amid a slower-than-expected rollout of its new multi-use sequencing chemistry and continued funding constraints in academic and government markets. Christian Henry stepped down as president and chief executive officer and will remain on PacBio’s board while serving as an advisor. Mark Van Oene, who previously led the company’s R&D operations and commercial organization, succeeded Henry as president and CEO effective immediately. → SpaceX’s First Earnings Report Could Decide Whether Shorts or Bulls Have Control Strategic Buy Lights Up This Biotech Stock: Time to Invest? “My priorities will be directly built on this foundation,” Van Oene said, citing plans to scale the company’s clinical-market approach globally, expand adoption of its SMRT Next chemistry and support larger sequencing projects. Consumables revenue rose 6% year over year to $20.1 million, supported by growth in PacBio’s installed base and clinical customer utilization. Shipments to clinical customers increased 67% from the prior-year period and represented a mid-teens percentage of total consumables shipments, according to Van Oene. → 3 Drone Stocks That Should Soar After the Summer Slump Instrument revenue declined 9% to $12.8 million. Chief Financial Officer Jim Gibson said the decrease reflected a lower average selling price resulting…Read full documentShow less
Interested in Pacific Biosciences of California, Inc.? Here are five stocks we like better. Leadership and outlook changed: CEO Christian Henry stepped down and was replaced immediately by Mark Van Oene. PacBio lowered its 2026 revenue forecast to $155 million–$165 million and pushed expected cash-flow breakeven to 2028. Q2 revenue was essentially flat at $39 million: Consumables revenue grew 6% to $20.1 million, but instrument revenue fell 9% to $12.8 million amid fewer Vega shipments and a lower average selling price. SMRT Next adoption is central to the growth strategy: The new multi-use chemistry lowers the cost of a 20x HiFi human genome by 30%, but customer validation and existing reagent inventories are delaying the expected consumables ramp until late 2026. Deciphering Disruption: Inside Cathie Wood's Latest Plays Pacific Biosciences of California (NASDAQ:PACB) reported second-quarter 2026 revenue of $39 million, roughly flat from $39.8 million a year earlier, while announcing an immediate leadership transition and lowering its full-year revenue outlook amid a slower-than-expected rollout of its new multi-use sequencing chemistry and continued funding constraints in academic and government markets. Christian Henry stepped down as president and chief executive officer and will remain on PacBio’s board while serving as an advisor. Mark Van Oene, who previously led the company’s R&D operations and commercial organization, succeeded Henry as president and CEO effective immediately. → SpaceX’s First Earnings Report Could Decide Whether Shorts or Bulls Have Control Strategic Buy Lights Up This Biotech Stock: Time to Invest? “My priorities will be directly built on this foundation,” Van Oene said, citing plans to scale the company’s clinical-market approach globally, expand adoption of its SMRT Next chemistry and support larger sequencing projects. Consumables revenue rose 6% year over year to $20.1 million, supported by growth in PacBio’s installed base and clinical customer utilization. Shipments to clinical customers increased 67% from the prior-year period and represented a mid-teens percentage of total consumables shipments, according to Van Oene. → 3 Drone Stocks That Should Soar After the Summer Slump Instrument revenue declined 9% to $12.8 million. Chief Financial Officer Jim Gibson said the decrease reflected a lower average selling price resulting from customer mix, including lower-priced strategic Revio placements, as well as fewer Vega system shipments. PacBio sold 20 Revio systems during the quarter, compared with 15 a year earlier. It sold 26 Vega systems, compared with 38 in the prior-year quarter. Cumulative shipments reached 366 Revio systems and 200 Vega systems. Sixty percent of second-quarter Revio placements went to new customers, while 45% were part of multi-instrument orders. Eighty-one percent of Vega shipments went to new customers. Van Oene said the majority of Revio placements during the quarter were to clinical accounts. He also said PacBio is seeing public health laboratories adopt Vega systems, including for wastewater testing and other applications outside traditional high-throughput whole-genome sequencing. → The Bitcoin Comeback May Already Be Underway—2 ETFs for Exposure Regional performance was mixed. Revenue in Europe, the Middle East and Africa increased 52% to $14.4 million, driven by clinical customers moving from pilot programs into routine production, growing Vega demand and a strategic multi-system Revio placement for a national genomics initiative. Americas revenue was $17.6 million, down slightly year over year, as uncertainty around NIH and broader academic funding affected capital purchases. Asia-Pacific revenue declined 45% to $7 million, reflecting the completion of a population sequencing program, funding headwinds and lower consumables demand during customer workflow validation. The company highlighted the global rollout of its SPRQ-Nx, or SMRT Next, chemistry for Revio. The chemistry allows customers to use each SMRT Cell up to three times, increases throughput per run and lowers the U.S. list price of a 20x HiFi human genome to $345, a 30% reduction from PacBio’s prior Spark chemistry, Van Oene said. More than one-third of PacBio’s installed base adopted software supporting the new workflow in June. The company expects more than half of its installed base to opt in by the end of the third quarter and the vast majority by year-end. Customers are currently validating the multi-use workflow and working through existing reagent inventories, leading PacBio to expect consumables growth to gain momentum later in 2026. Van Oene said PacBio expects the SPRQ-Nx transition to continue through the third quarter, with consumables usage beginning to scale toward the end of the year. The company also plans to launch SPRQ-Nx chemistry for Vega in late August, increasing output to up to 90 gigabases per run while reducing DNA input requirements. PacBio cited recent publications supporting long-read sequencing in clinical diagnostics. Van Oene said a June 13 article in The New England Journal of Medicine reported 96.4% concordance between long-read genome sequencing and standard-of-care testing in rare disease diagnostics. In the study, long-read sequencing improved or refined diagnoses in 3.4% of cases, while standard testing identified variants missed by long reads in 0.2% of cases. The company also referenced a Nature Genetics article discussing “near-perfect genome sequencing” and a preprint from the HiFi Solves Sub-fertility Consortium in Asia-Pacific. PacBio said those findings reinforce its view that long-read sequencing can support a broader shift toward a single, more comprehensive testing workflow. Second-quarter non-GAAP gross margin was 36%, down from 38% a year earlier. Gibson attributed the decline to compute cost inflation, lower manufacturing volumes and $1.1 million in costs related to moving Vega manufacturing in-house. PacBio expects Vega manufacturing transition costs to conclude by the end of 2026. Non-GAAP operating expenses declined 3% to $56.1 million. The company reported a non-GAAP net loss of $41.9 million, or $0.14 per share, compared with a loss of $40 million, or $0.13 per share, in the prior-year quarter. PacBio ended the quarter with approximately $236.9 million in unrestricted cash equivalents and investments, down from $279.5 million at the end of 2025. The company recently initiated a reorganization that will reduce its workforce by about 40 employees. Van Oene said the changes integrate marketing more closely with the commercial organization, particularly around clinical customers, while reducing management layers. He said key R&D platform projects were not affected. For 2026, PacBio reduced its revenue outlook to $155 million to $165 million. It now expects non-GAAP gross margin of 35% to 37%, non-GAAP operating expenses of $215 million to $220 million and year-end cash of approximately $175 million to $185 million. Gibson said the company expects the restructuring to reduce 2027 compensation and related expenses by approximately $15 million to $20 million. PacBio also expects another $15 million to $20 million of annual savings after it moves beyond development spending on its high-throughput platform. However, the company now expects to reach cash-flow breakeven in 2028, compared with its previous expectation of the end of 2027. Pacific Biosciences of California, Inc develops, manufactures and sells high-performance DNA sequencing systems for genetic and genomic analysis. The company's proprietary single-molecule, real-time (SMRT) sequencing technology is designed to enable long-read sequencing, offering high accuracy for applications such as de novo genome assembly, transcriptome characterization and structural variation analysis. Pacific Biosciences markets a suite of instruments, including the Sequel and Sequel IIe systems, alongside reagents, consumables and data analysis software to support a range of life science research. Founded in 2004 and headquartered in Menlo Park, California, Pacific Biosciences has expanded its global reach by serving academic institutions, biotechnology and pharmaceutical companies, and government research centers across North America, Europe and Asia. This instant news alert was generated by narrative science technology and financial data from MarketBeat in order to provide readers with the fastest reporting and unbiased coverage. Please send any questions or comments about this story to [email protected]. The article "Pacific Biosciences of California Q2 Earnings Call Highlights" was originally published by MarketBeat. View MarketBeat's top stocks for August 2026.
Investor releaseQuarter not tagged2026-08-06PacBio Q2 Earnings Meet Estimates, Revenues Miss, 2026 Sales View Cut
Zacks
PacBio Q2 Earnings Meet Estimates, Revenues Miss, 2026 Sales View Cut
Pacific Biosciences of California, Inc. PACB, popularly known as PacBio, reported an adjusted loss per share of 14 cents for the second quarter of 2026, wider than the year-ago adjusted loss of 13 cents per share. The figure came in line with the Zacks Consensus Estimate. The company’s GAAP loss per share was 14 cents in the quarter, flat year over year. PacBio registered total revenues of $39 million, down 2% year over year. The figure missed the Zacks Consensus Estimate by 4.2%. Consumables growth and higher Revio placements were offset by weaker instrument sales and a sharp revenue decline in Asia Pacific. Shares of the company lost around 1.5% during yesterday’s after-hours trading. Year to date, the stock has declined 30.5% compared with the industry’s fall of 10%. However, the broader S&P 500 Index has increased 12.8% in the same time frame. Image Source: Zacks Investment Research Americas revenues were $17.6 million, down 0.6% year over year. Continued uncertainty surrounding NIH, academic and government funding weighed on capital purchasing, though clinical and commercial customer activity remained resilient. Asia-Pacific revenues totaled $7 million, down 45% year over year. The decrease reflected the completion of a significant population-sequencing program, weaker academic and government demand and lower consumables purchases as customers prepared for the SPRQ-Nx transition. EMEA revenues increased 52% year over year to $14.4 million. Growth was driven by clinical customers moving from pilot programs into routine production, stronger Vega demand and a strategic multi-system Revio placement supporting a national genomics initiative. In the quarter under review, total Product revenues amounted to $32.9 million, down 0.4% from the year-ago quarter. Within the Product segment, Instrument revenues were $12.8 million, down 9.9% year over year. The decline reflected a lower average selling price, including strategic Revio placements at key accounts, and fewer Vega shipments amid academic and government funding constraints. Instrument revenues in the quarter included 20 Revio sequencing systems and 26 Vega sequencing systems. PACB ended the quarter with 366 cumulative Revio system shipments and 200 cumulative Vega system shipments. Consumables revenues for the quarter were $20.1 million, up 6.3% from the prior-year quarter, supported by installed-base expa…Read full documentShow less
Pacific Biosciences of California, Inc. PACB, popularly known as PacBio, reported an adjusted loss per share of 14 cents for the second quarter of 2026, wider than the year-ago adjusted loss of 13 cents per share. The figure came in line with the Zacks Consensus Estimate. The company’s GAAP loss per share was 14 cents in the quarter, flat year over year. PacBio registered total revenues of $39 million, down 2% year over year. The figure missed the Zacks Consensus Estimate by 4.2%. Consumables growth and higher Revio placements were offset by weaker instrument sales and a sharp revenue decline in Asia Pacific. Shares of the company lost around 1.5% during yesterday’s after-hours trading. Year to date, the stock has declined 30.5% compared with the industry’s fall of 10%. However, the broader S&P 500 Index has increased 12.8% in the same time frame. Image Source: Zacks Investment Research Americas revenues were $17.6 million, down 0.6% year over year. Continued uncertainty surrounding NIH, academic and government funding weighed on capital purchasing, though clinical and commercial customer activity remained resilient. Asia-Pacific revenues totaled $7 million, down 45% year over year. The decrease reflected the completion of a significant population-sequencing program, weaker academic and government demand and lower consumables purchases as customers prepared for the SPRQ-Nx transition. EMEA revenues increased 52% year over year to $14.4 million. Growth was driven by clinical customers moving from pilot programs into routine production, stronger Vega demand and a strategic multi-system Revio placement supporting a national genomics initiative. In the quarter under review, total Product revenues amounted to $32.9 million, down 0.4% from the year-ago quarter. Within the Product segment, Instrument revenues were $12.8 million, down 9.9% year over year. The decline reflected a lower average selling price, including strategic Revio placements at key accounts, and fewer Vega shipments amid academic and government funding constraints. Instrument revenues in the quarter included 20 Revio sequencing systems and 26 Vega sequencing systems. PACB ended the quarter with 366 cumulative Revio system shipments and 200 cumulative Vega system shipments. Consumables revenues for the quarter were $20.1 million, up 6.3% from the prior-year quarter, supported by installed-base expansion and continued Revio utilization. Shipments to clinical customers increased 67% and represented a mid-teens percentage of total consumables shipments. Annualized Revio pull-through per system was approximately $202,000 in the quarter. Growth was partly tempered by customers using existing inventory and validating workflows ahead of broader SPRQ-Nx adoption. Service and other revenues totaled $6.1 million, down 9.4% year over year. In the quarter under review, PacBio’s adjusted gross profit decreased 8.3% year over year to $13.9 million. The adjusted gross margin contracted 200 basis points to 36%. Sales, general and administrative expenses declined 7.7% year over year to $33.4 million. Research and development expenses increased 2.2% year over year to $23 million. Adjusted total operating expenses of $56.1 million decreased 3.4% year over year. Total operating loss was $44.6 million in the reported quarter compared with the prior-year quarter’s $44.9 million. PacBio exited the second quarter of 2026 with cash and investments of $236.9 million compared with $275.9 million at the end of the first quarter of 2026. PacBio reduced its 2026 revenue guidance to $155-$165 million from the prior range of $165-$175 million. The Zacks Consensus Estimate is pegged at $165.8 million. The company now expects an adjusted gross margin of 35%-37%. Adjusted operating expenses are projected at $215-$220 million, down $5 million from the previous guidance range. Pacific Biosciences of California, Inc. price-consensus-eps-surprise-chart | Pacific Biosciences of California, Inc. Quote PacBio exited the second quarter of 2026 with mixed results, wherein adjusted earnings met the Zacks Consensus Estimate while revenues missed the same. Growth in consumables revenues, strong clinical demand and an increase in EMEA revenues were encouraging. Gains were partly offset by softer instrument revenues, funding constraints in the Americas and a sharp revenue decline in Asia Pacific. PacBio advanced the global commercial rollout of SPRQ-Nx chemistry, which lowers the U.S. list price of a HiFi whole genome to $345 through multi-use SMRT Cells. The chemistry enhances methylation detection and incorporates DeepConsensus, an AI-powered algorithm co-developed with Google. More than one-third of the installed base had opted for SPRQ-Nx by June, while the company will launch SPRQ-Nx on the Vega platform in August to expand throughput to 90 gigabases per run. Commercial momentum included multi-system Revio orders, a new population-scale customer and continued sample delivery for Basecamp Research. PacBio gained scientific validation through publications in the New England Journal of Medicine and Nature Genetics, along with a HiFi Solves subfertility preprint. The company’s growth strategy centers on replicating EMEA’s clinical success globally, expanding population-scale sequencing and operating with a leaner cost structure. However, PacBio continues to face funding-related weakness in the Americas and Asia-Pacific, slower-than-expected SPRQ-Nx adoption as customers complete workflow validation and cost pressures from memory, compute and Vega manufacturing transition. These factors prompted the company to lower its 2026 revenue and gross margin guidance while pushing its cash flow breakeven target to 2028. PacBio currently carries a Zacks Rank #3 (Hold). Some better-ranked stocks from the broader medical space are West Pharmaceutical WST, McKesson MCK and Cardinal Health CAH, each carrying a Zacks Rank #2 (Buy) at present. You can see the complete list of today’s Zacks #1 (Strong Buy) Rank stocks here. West Pharmaceutical reported second-quarter 2026 adjusted earnings per share (EPS) of $2.37, which beat the Zacks Consensus Estimate by 13.9%. Revenues of $872.3 million surpassed the Zacks Consensus Estimate by 4.2%. West Pharmaceutical has an estimated long-term earnings growth rate of 16%. WST’s earnings surpassed estimates in the trailing four quarters, the average surprise being 17.4%. McKesson reported a first-quarter fiscal 2027 adjusted EPS of $9.93, which beat the Zacks Consensus Estimate by 5.2%. Revenues of $105.4 billion surpassed the Zacks Consensus Estimate by 0.95%. McKesson has an estimated long-term earnings growth rate of 13.7%. MCK’s earnings surpassed estimates in the trailing four quarters, the average surprise being 4.3%. Cardinal Health reported a third-quarter fiscal 2026 adjusted EPS of $3.17, which beat the Zacks Consensus Estimate by 13.2%. Revenues of $60.94 billion missed the Zacks Consensus Estimate by 2.3%. Cardinal Health has an estimated long-term earnings growth rate of 17%. CAH’s earnings surpassed estimates in the trailing four quarters, the average surprise being 10.3%. Want the latest recommendations from Zacks Investment Research? Today, you can download 7 Best Stocks for the Next 30 Days. Click to get this free report Pacific Biosciences of California, Inc. (PACB) : Free Stock Analysis Report Cardinal Health, Inc. (CAH) : Free Stock Analysis Report McKesson Corporation (MCK) : Free Stock Analysis Report West Pharmaceutical Services, Inc. (WST) : Free Stock Analysis Report This article originally published on Zacks Investment Research (zacks.com). Zacks Investment Research
Investor releaseQuarter not tagged2026-08-05Pacific Biosciences: Q2 Earnings Snapshot
Associated Press
Pacific Biosciences: Q2 Earnings Snapshot
MENLO PARK, Calif. (AP) — MENLO PARK, Calif. (AP) — Pacific Biosciences of California Inc. (PACB) on Wednesday reported a loss of $44.7 million in its second quarter. On a per-share basis, the Menlo Park, California-based company said it had a loss of 14 cents. The maker of genetic analysis technology posted revenue of $39 million in the period. Pacific Biosciences expects full-year revenue in the range of $155 million to $165 million. _____ This story was generated by Automated Insights (http://automatedinsights.com/ap) using data from Zacks Investment Research. Access a Zacks stock report on PACB at https://www.zacks.com/ap/PACB
Investor releaseQuarter not tagged2026-08-05PacBio (NASDAQ:PACB) Reports Sales Below Analyst Estimates In Q2 CY2026 Earnings
StockStory
PacBio (NASDAQ:PACB) Reports Sales Below Analyst Estimates In Q2 CY2026 Earnings
Genomics company Pacific Biosciences of California (NASDAQ:PACB) fell short of the market’s revenue expectations in Q2 CY2026, with sales falling 1.9% year on year to $39.01 million. Its non-GAAP loss of $0.14 per share was 10.4% below analysts’ consensus estimates. Is now the time to buy PacBio? Find out in our full research report. Revenue: $39.01 million vs analyst estimates of $39.91 million (1.9% year-on-year decline, 2.3% miss) Adjusted EPS: -$0.14 vs analyst expectations of -$0.13 (10.4% miss) Operating Margin: -114%, down from -113% in the same quarter last year Market Capitalization: $447.3 million Pioneering what scientists call "HiFi long-read sequencing," recognized as Nature Methods' method of the year for 2022, Pacific Biosciences (NASDAQ:PACB) develops advanced DNA sequencing systems that enable scientists and researchers to analyze genomes with unprecedented accuracy and completeness. Reviewing a company’s long-term sales performance reveals insights into its quality. Even a bad business can shine for one or two quarters, but a top-tier one grows for years. Thankfully, PacBio’s 8.5% annualized revenue growth over the last five years was decent. Its growth was slightly above the average healthcare company and shows its offerings resonate with customers. We at StockStory place the most emphasis on long-term growth, but within healthcare, a half-decade historical view may miss recent innovations or disruptive industry trends. PacBio’s recent performance marks a sharp pivot from its five-year trend as its revenue has shown annualized declines of 8.2% over the last two years. This quarter, PacBio missed Wall Street’s estimates and reported a rather uninspiring 1.9% year-on-year revenue decline, generating $39.01 million of revenue. Looking ahead, sell-side analysts expect revenue to grow 14.2% over the next 12 months, an improvement versus the last two years. This projection is healthy and implies its newer products and services will fuel better top-line performance. ALSO WORTH WATCHING: Nvidia’s Quiet Partner. Nvidia’s chips cost a hundred grand. The connectors that make them work cost even more. One company makes them all. Every AI server needs specialized infrastructure the chip companies don’t make. High-speed cables. Power connectors. Thermal sensors. This 90-year-old company built a monopoly on it. The AI boom just started. This stock is sti…Read full documentShow less
Genomics company Pacific Biosciences of California (NASDAQ:PACB) fell short of the market’s revenue expectations in Q2 CY2026, with sales falling 1.9% year on year to $39.01 million. Its non-GAAP loss of $0.14 per share was 10.4% below analysts’ consensus estimates. Is now the time to buy PacBio? Find out in our full research report. Revenue: $39.01 million vs analyst estimates of $39.91 million (1.9% year-on-year decline, 2.3% miss) Adjusted EPS: -$0.14 vs analyst expectations of -$0.13 (10.4% miss) Operating Margin: -114%, down from -113% in the same quarter last year Market Capitalization: $447.3 million Pioneering what scientists call "HiFi long-read sequencing," recognized as Nature Methods' method of the year for 2022, Pacific Biosciences (NASDAQ:PACB) develops advanced DNA sequencing systems that enable scientists and researchers to analyze genomes with unprecedented accuracy and completeness. Reviewing a company’s long-term sales performance reveals insights into its quality. Even a bad business can shine for one or two quarters, but a top-tier one grows for years. Thankfully, PacBio’s 8.5% annualized revenue growth over the last five years was decent. Its growth was slightly above the average healthcare company and shows its offerings resonate with customers. We at StockStory place the most emphasis on long-term growth, but within healthcare, a half-decade historical view may miss recent innovations or disruptive industry trends. PacBio’s recent performance marks a sharp pivot from its five-year trend as its revenue has shown annualized declines of 8.2% over the last two years. This quarter, PacBio missed Wall Street’s estimates and reported a rather uninspiring 1.9% year-on-year revenue decline, generating $39.01 million of revenue. Looking ahead, sell-side analysts expect revenue to grow 14.2% over the next 12 months, an improvement versus the last two years. This projection is healthy and implies its newer products and services will fuel better top-line performance. ALSO WORTH WATCHING: Nvidia’s Quiet Partner. Nvidia’s chips cost a hundred grand. The connectors that make them work cost even more. One company makes them all. Every AI server needs specialized infrastructure the chip companies don’t make. High-speed cables. Power connectors. Thermal sensors. This 90-year-old company built a monopoly on it. The AI boom just started. This stock is still flying under the radar. Claim The Stock Ticker Here for FREE. PacBio’s high expenses have contributed to an average adjusted operating margin of negative 151% over the last five years. Unprofitable healthcare companies require extra attention because they could get caught swimming naked when the tide goes out. It’s hard to trust that the business can endure a full cycle. On the plus side, PacBio’s adjusted operating margin rose by 86.4 percentage points over the last five years, as its sales growth gave it operating leverage. Zooming in on its more recent performance, we can see the company’s trajectory is intact as its margin has also increased by 51.2 percentage points on a two-year basis. PacBio’s adjusted operating margin was negative 114% this quarter. We track the long-term change in earnings per share (EPS) for the same reason as long-term revenue growth. Compared to revenue, however, EPS highlights whether a company’s growth is profitable. Although PacBio’s full-year earnings are still negative, it reduced its losses and improved its EPS by 11.6% annually over the last five years. The next few quarters will be critical for assessing its long-term profitability. In Q2, PacBio reported adjusted EPS of negative $0.14, down from negative $0.13 in the same quarter last year. This print missed analysts’ estimates. Over the next 12 months, Wall Street expects PacBio to improve its earnings losses. Analysts forecast its full-year EPS will improve from negative $0.50 to negative $0.48. We struggled to find many positives in these results. Its revenue missed and its EPS fell short of Wall Street’s estimates. Overall, this was a weaker quarter. The stock traded down 1.1% to $1.28 immediately following the results. PacBio may have had a tough quarter, but does that actually create an opportunity to invest right now? If you’re making that decision, you should consider the bigger picture of valuation, business qualities, as well as the latest earnings. We cover that in our actionable full research report which you can read here, it’s free.
Investor releaseQuarter not tagged2026-08-05PacBio Announces Second Quarter 2026 Financial Results
GlobeNewswire
PacBio Announces Second Quarter 2026 Financial Results
MENLO PARK, Calif., Aug. 05, 2026 (GLOBE NEWSWIRE) -- PacBio (NASDAQ: PACB) today announced financial results for the quarter ended June 30, 2026. Recent Business Highlights Total revenue of $39.0 million was driven by growing consumables and new Revio and Vega placements as the Company commenced its full rollout of SPRQ-Nx chemistry. Instrument revenue consisted of both single-system and multi-system orders, including an order for several Revio systems from a new population-scale customer Commenced global commercial rollout of SPRQ-Nx, delivering whole genome sequencing at $345 USD list price per genome with enhanced methylation detection and DeepConsensus, an AI-powered consensus algorithm co-developed with Google Commenced sequencing and sample delivery for Basecamp Research, a frontier AI lab for therapeutic design, marking a significant operational milestone for PacBio's largest population-scale program to date Published in a landmark New England Journal of Medicine study, "Clinical Long-Read Genome Sequencing for Rare-Disease Diagnostics." The publication demonstrates that HiFi long-read sequencing is a clinically effective first-tier diagnostic test that improves diagnostic yield while simplifying the laboratory workflow, reducing turnaround time, and enhancing the overall economics of rare disease diagnostics Published in a Nature Genetics article, “Near-perfect genome sequencing in medical genetics.” The publication highlights long-read sequencing as a pillar of near-perfect genome sequencing (NPGS), alongside diploid genome assembly, pangenome references, and AI-driven variant interpretation Contributed to a published preprint from the HiFi Solves Sub-fertility Consortium in Asia Pacific. The preprint demonstrates that PacBio HiFi whole genome sequencing can provide a more complete view of reproductive genetics in one workflow Implemented restructuring actions primarily to streamline marketing and R&D organizations, strengthen the go-to-market commercial organization, and drive greater cost discipline going forward Second quarter results: Gross profit and margin, operating expenses, net loss, and net loss per share are reported on a GAAP and non-GAAP basis. The non-GAAP measures are described below and reconciled to the corresponding GAAP measures at the end of this release. GAAP gross profit for the second quarter of 2026 was $12.6 million compare…Read full documentShow less
MENLO PARK, Calif., Aug. 05, 2026 (GLOBE NEWSWIRE) -- PacBio (NASDAQ: PACB) today announced financial results for the quarter ended June 30, 2026. Recent Business Highlights Total revenue of $39.0 million was driven by growing consumables and new Revio and Vega placements as the Company commenced its full rollout of SPRQ-Nx chemistry. Instrument revenue consisted of both single-system and multi-system orders, including an order for several Revio systems from a new population-scale customer Commenced global commercial rollout of SPRQ-Nx, delivering whole genome sequencing at $345 USD list price per genome with enhanced methylation detection and DeepConsensus, an AI-powered consensus algorithm co-developed with Google Commenced sequencing and sample delivery for Basecamp Research, a frontier AI lab for therapeutic design, marking a significant operational milestone for PacBio's largest population-scale program to date Published in a landmark New England Journal of Medicine study, "Clinical Long-Read Genome Sequencing for Rare-Disease Diagnostics." The publication demonstrates that HiFi long-read sequencing is a clinically effective first-tier diagnostic test that improves diagnostic yield while simplifying the laboratory workflow, reducing turnaround time, and enhancing the overall economics of rare disease diagnostics Published in a Nature Genetics article, “Near-perfect genome sequencing in medical genetics.” The publication highlights long-read sequencing as a pillar of near-perfect genome sequencing (NPGS), alongside diploid genome assembly, pangenome references, and AI-driven variant interpretation Contributed to a published preprint from the HiFi Solves Sub-fertility Consortium in Asia Pacific. The preprint demonstrates that PacBio HiFi whole genome sequencing can provide a more complete view of reproductive genetics in one workflow Implemented restructuring actions primarily to streamline marketing and R&D organizations, strengthen the go-to-market commercial organization, and drive greater cost discipline going forward Second quarter results: Gross profit and margin, operating expenses, net loss, and net loss per share are reported on a GAAP and non-GAAP basis. The non-GAAP measures are described below and reconciled to the corresponding GAAP measures at the end of this release. GAAP gross profit for the second quarter of 2026 was $12.6 million compared to $14.7 million during the second quarter of 2025. Non-GAAP gross profit for the second quarter of 2026 was $13.9 million compared to $15.2 million for the second quarter of 2025. GAAP gross margin was 32% for the second quarter of 2026 compared to 37% for the second quarter of 2025. Non-GAAP gross margin was 36% for the second quarter of 2026 compared to 38% for the second quarter of 2025. The decline in non-GAAP gross margin was primarily driven by higher compute and memory costs, Vega manufacturing transition costs, and lower Revio average selling prices associated with strategic multi-system customer placements. GAAP operating expenses totaled $57.2 million for the second quarter of 2026 compared to $59.5 million for the second quarter of 2025. Non-GAAP operating expenses totaled $56.1 million for the second quarter of 2026 compared to $58.1 million for the second quarter of 2025. GAAP and non-GAAP operating expenses for the second quarter of 2026 and the second quarter of 2025 included non-cash share-based compensation of $8.6 million and $11.0 million, respectively. GAAP net loss for the second quarter of 2026 was $44.7 million compared to $41.9 million for the second quarter of 2025. Non-GAAP net loss for the second quarter of 2026 was $41.9 million compared to $40.0 million for the second quarter of 2025. GAAP net loss per share for the second quarter of 2026 was $0.14 compared to $0.14 for the second quarter of 2025. Non-GAAP net loss per share for the second quarter of 2026 was $0.14 compared to $0.13 for the second quarter of 2025. 2026 Financial Outlook PacBio expects revenue for the full year 2026 to be in the range of $155 million to $165 million. Quarterly Conference Call Information Management will host a quarterly conference call today at 4:30 p.m. Eastern Time to review financial results for the second quarter ended June 30, 2026. Investors can access the call by dialing 1-888-349-0136 (or 1-412-317-0459 for international callers) and requesting to join the “PacBio Q2 Earnings Call". The call will be webcast live and available for replay at PacBio's website at https://investor.pacificbiosciences.com. About PacBio PacBio (NASDAQ: PACB) is a premier life science technology company that designs, develops, and manufactures advanced sequencing solutions to help scientists and clinical researchers resolve genetically complex problems. Our products and technologies, which primarily consist of our HiFi long-read sequencing systems, address solutions across a broad set of research applications, including human germline sequencing, plant and animal sciences, infectious disease and microbiology, oncology, and other emerging applications. For more information, please visit www.pacb.com and follow @PacBio. PacBio products are provided for Research Use Only. Not for use in diagnostic procedures. Statement regarding use of non‐GAAP financial measures PacBio reports non‐GAAP results for basic net income (loss) per share, net income (loss), gross margins, gross profit (loss) and operating expenses in addition to, and not as a substitute for, or because it believes that such information is superior to, financial measures calculated in accordance with GAAP. PacBio believes that non-GAAP financial information, when taken collectively, may be helpful to investors because it provides consistency and comparability with past financial performance. However, non-GAAP financial information is presented for supplemental informational purposes only, has limitations as an analytical tool and should not be considered in isolation or as a substitute for financial information presented in accordance with GAAP. In addition, other companies may calculate similarly titled non-GAAP measures differently or may use other measures to evaluate their performance, all of which could reduce the usefulness of PacBio’s non-GAAP financial measures as tools for comparison. PacBio's financial measures under GAAP include substantial charges that are listed in the itemized reconciliations between GAAP and non‐GAAP financial measures included in this press release. PacBio excludes recurring charges from its non-GAAP financial statements, including amortization of acquired intangible assets and changes in fair value of contingent consideration, and further excludes infrequent and limited charges including impairment charges, restructuring-related expenses for discrete restructuring events, settlement charges, disposition of short-read assets, benefits from income taxes and other adjustments and rounding differences. Management has excluded the effects of these items in non‐GAAP measures to assist investors in analyzing and assessing past and future operating performance. In addition, management uses non-GAAP measures to compare PacBio’s performance relative to forecasts and strategic plans and to benchmark its performance externally against competitors. PacBio encourages investors to carefully consider its results under GAAP, as well as its supplemental non‐GAAP information and the reconciliation between these presentations, to more fully understand its business. A reconciliation of PacBio’s non-GAAP financial measures to their most directly comparable financial measure stated in accordance with GAAP has been provided in the financial statement tables included in this press release. PacBio is unable to reconcile future-looking non-GAAP guidance without unreasonable effort because certain items that impact this measure are out of PacBio's control and/or cannot be reasonably predicted at this time. Forward-Looking Statements This press release contains “forward-looking statements” within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and the U.S. Private Securities Litigation Reform Act of 1995. All statements other than statements of historical fact are forward-looking statements, including, but not limited to, statements relating to PacBio’s initiatives as well as the expected financial impact and timing of these plans and initiatives, including PacBio's expectations regarding long-read sequencing and SPRQ-Nx; PacBio's expectations regarding its restructuring efforts; PacBio’s financial guidance and expectations for future periods; new and continued reception of PacBio’s products and their expansion into new or existing markets; and the availability, uses, accuracy, coverage, advantages, quality or performance of, or benefits or expected benefits of using, PacBio products or technologies. Reported results and orders for any instrument system should not be considered an indication of future performance. You should not place undue reliance on forward-looking statements because they are subject to assumptions, risks, and uncertainties and could cause actual outcomes and results to differ materially from currently anticipated results, including, but not limited to, challenges inherent in developing, manufacturing, launching, marketing and selling new products, and achieving anticipated new sales; potential cancellation of existing instrument orders; assumptions, risks and uncertainties related to the ability to attract new customers and retain and grow sales from existing customers; risks related to PacBio's ability to successfully execute and realize the benefits of acquisitions; the impact of new, increased or enhanced tariffs and export restrictions; rapidly changing technologies and extensive competition in genomic sequencing; unanticipated increases in costs or expenses; high costs of computer memory components; interruptions or delays in the supply of components or materials for, or manufacturing of, PacBio products and products under development; potential product performance and quality issues and potential delays in development timelines; the possible loss of key employees, customers, or suppliers; customers and prospective customers curtailing or suspending activities using PacBio's products; third-party claims alleging infringement of patents and proprietary rights or seeking to invalidate PacBio's patents or proprietary rights; risks associated with international operations; and other risks associated with general macroeconomic conditions and global economic or political instability, including war and other international conflicts, such as the conflicts in the Middle East. Additional factors that could materially affect actual results can be found in PacBio's most recent filings with the Securities and Exchange Commission, including PacBio's most recent reports on Forms 8-K, 10-K, and 10-Q, and include those listed under the caption “Risk Factors.” These forward-looking statements are based on current expectations and speak only as of the date hereof; except as required by law, PacBio disclaims any obligation to revise or update these forward-looking statements to reflect events or circumstances in the future, even if new information becomes available. The unaudited condensed consolidated financial statements that follow should be read in conjunction with the notes set forth in PacBio's Quarterly Report on Form 10-Q when filed with the Securities and Exchange Commission. Contacts Investors:[email protected] Media:[email protected] (1) Balances for the three months ended June 30, 2025 include restructuring costs. Refer to the Reconciliation of Non-GAAP Financial Measures table below for additional information on such costs and related amounts. (2) Balances for the three months ended June 30, 2026 and March 31, 2026 include litigation settlement charges and related legal fees in connection with the agreement entered into with Personal Genomics of Taiwan, Inc. Refer to the Reconciliation of Non-GAAP Financial Measures table below for additional information on such costs and related amounts. (3) Balances for the three months ended June 30, 2026 and March 31, 2026 include amounts related to the disposition of short-read assets, including the gain on the sale of certain assets related to our short-read DNA sequencing technology and related clustering, sequencing reagent, and detection technologies, and related non-recurring customer transition costs. Refer to the Reconciliation of Non-GAAP Financial Measures table below for additional information on such costs and related amounts. (4) Balance for the three months ended June 30, 2026 includes interest expense related to the Personal Genomics of Taiwan, Inc. settlement liability. (1) Balances for the three and six months ended June 30, 2025 include restructuring costs. Refer to the Reconciliation of Non-GAAP Financial Measures table below for additional information on such costs and related amounts. (2) In-process research and development ("IPR&D") impairment charge during the six months ended June 30, 2025 was driven primarily by macroeconomic factors and restructuring initiatives, including the focus on long-read innovation, resulting in changes to the timing and amounts of cash flows. (3) Balances for the three and six months ended June 30, 2026 include litigation settlement charges and related legal fees in connection with the agreement entered into with Personal Genomics of Taiwan, Inc. Refer to the Reconciliation of Non-GAAP Financial Measures table below for additional information on such costs and related amounts. (4) Balances for the three and six months ended June 30, 2026 include amounts related to the disposition of short-read assets, including the gain on the sale of certain assets related to our short-read DNA sequencing technology and related clustering, sequencing reagent, and detection technologies, and related non-recurring customer transition costs. Refer to the Reconciliation of Non-GAAP Financial Measures table below for additional information on such costs and related amounts. (5) Balance for the six months ended June 30, 2025 includes accelerated amortization of acquired intangible assets related to restructuring initiatives. Refer to the Reconciliation of Non-GAAP Financial Measures table below for additional information on such costs and related amounts. (6) Change in fair value of contingent consideration during the six months ended June 30, 2025 was due to fair value adjustments of milestone payments payable upon the achievement of a milestone event. (1) Change in fair value of contingent consideration during the six months ended June 30, 2025 was due to fair value adjustments of milestone payments payable upon the achievement of a milestone event. (2) Balances for the three months ended June 30, 2026 and March 31, 2026 and the six months ended June 30, 2026 include litigation settlement charges and related legal fees in connection with the agreement entered into with Personal Genomics of Taiwan, Inc. (3) Balances for the three and six months ended June 30, 2026 include amortization of a patent license acquired in connection with the agreement entered into with Personal Genomics of Taiwan, Inc. (4) Balances for the three months ended June 30, 2026 and March 31, 2026 and the six months ended June 30, 2026 include amounts related to the disposition of short-read assets, including the gain on the sale of certain assets related to our short-read DNA sequencing technology and related clustering, sequencing reagent, and detection technologies, and related non-recurring customer transition costs. (5) Interest expense for the three and six months ended June 30, 2026 is related to the liability incurred in connection with the agreement entered into with Personal Genomics of Taiwan, Inc. (6) A deferred income tax benefit during the six months ended June 30, 2025 is primarily related to the change in the deferred tax liability balance resulting from the accelerated amortization of acquired intangible assets and IPR&D impairment. (7) Restructuring-related costs incurred in connection with the 2025 plan during the three and six months ended June 30, 2025 consist primarily of costs included in cost of revenue related to excess inventory and purchase commitment losses, as well as costs included in operating expenses related to employee separation, accelerated depreciation, IPR&D impairment, and accelerated amortization of acquired intangibles.
TranscriptFY2026 Q22026-08-05FY2026 Q2 earnings call transcript
Earnings source - 67 paragraphs
FY2026 Q2 earnings call transcript
Good day, and welcome to PacBio's second quarter of 2026 earnings call. All participants will be in a listen-only mode for the duration of the call. Should you need any assistance today, please signal a conference specialist by pressing the star key followed by zero. After today's presentation, there will be an opportunity to ask questions. If you'd like to ask a question, you may press star then one on your telephone keypad to join the queue. To withdraw a question for any reason, please press star then two. Also, please be aware that today's call is being recorded. I'd now like to turn the call over to Caylene Parrish from Gilmartin Group. Please go ahead.
Good afternoon and welcome to PacBio's second quarter 2026 earnings conference call. With me today are Mark Van Oene, President and Chief Executive Officer, Jim Gibson, Chief Financial Officer, and Christian Henry, PacBio board member and advisor. Earlier today, we issued a press release outlining the financial results we'll be discussing on today's call, a copy of which is available on the investors section of our website at www.pacb.com or as furnished on Form 8-K, available on the Securities and Exchange Commission website at www.sec.gov. A copy of our earnings presentation is also available on the investors section of our website. On today's call, we will make forward-looking statements, including, among others, statements providing predictions, estimates, expectations, and guidance.
You should not place undue reliance on forward-looking statements because they are subject to assumptions, risks, and uncertainties that could cause our actual results to differ materially from those projected or discussed. Please review our SEC filings, including our most recent Form 10-Q and 10-K, and our press releases to better understand the risks and uncertainties that could cause results to differ. We disclaim any obligation to update or revise these forward-looking statements except as required by law. We also present certain financial information on a non-GAAP basis, which is not prepared under a comprehensive set of accounting rules and should only be used to supplement an understanding of the company's operating results as reported under US GAAP. Reconciliations between historical US GAAP and non-GAAP results are presented in our earnings release, which is available on the investors section of our website.
For future periods, we're unable to reconcile non-GAAP gross margin and non-GAAP operating expenses without unreasonable effort due to the uncertainty regarding, among other matters, certain acquisition-related items that may arise during the year. A recording of today's call will be available shortly after the live call in the investors section of our website. Those electing to use the replay are cautioned that forward-looking statements may differ or change materially after the completion of the live call. I'll now turn the call over to Christian.
Thank you, and good afternoon, everyone. Earlier today, we announced that I am stepping down as President and Chief Executive Officer of PacBio and that Mark Van Oene will lead the company as President and Chief Executive Officer, effective immediately. I will remain on the board of directors and become an advisor to Mark as he drives PacBio's strategy forward. Mark joined PacBio shortly after I did, and in that time, he has led the R&D operations and commercial organizations. His deep understanding of the genomics and clinical markets will be invaluable to the company as we move deeper into supporting clinical sequencing around the globe. Additionally, his ability to successfully lead strong teams will ensure that PacBio executes well into its future. I am proud of what we have accomplished over the nearly six years that I have had the privilege of leading PacBio.
We have developed and launched groundbreaking new long-read sequencers that have dramatically improved the scale and economics of long-read sequencing. These platforms are enabling researchers and clinicians to dramatically improve their ability to understand the impact of genetic variation on disease, moving us closer to achieving our mission of enabling the promise of genomics to improve human health. Finally, I want to thank our employees, customers, and collaborators for their support. I look forward to advising Mark as he leads the company into its next phase of growth and continuing to serve on the board of directors. With that, I'll now turn the call over to Mark. Mark?
Thank you, and good afternoon, everyone. On behalf of the team, thank you, Christian, for your six years of leadership. I'm honored and excited to step into this seat, and I'm grateful for the support of you, our leadership team and board, who I've been working closely with to execute the seamless transition. Since joining in 2021 as Chief Operating Officer, I had the pleasure of leading the R&D organization that built the Revio and Vega instruments, and more recently oversaw development and rollout of the multi-use SMRT Next chemistry. My recent commercial leadership focus has leveraged the strength of our clinical account engagement, which has proven particularly effective in the EMEA region.
Looking ahead, my priorities will be directly built on this foundation, taking what's worked in EMEA and scaling it globally, driving SMRT Next adoption across accounts, and growing our understanding of disease biology and biomarker discovery by enabling greater high-throughput, cost efficiency, and data access. I'm energized by the multiple catalysts in front of us and confident in what's ahead as we take PacBio into its next phase of growth. Part of that next phase means operating with a leaner team focused on our highest priority growth drivers. I want to address a targeted reorganization we initiated late last week. We are integrating our marketing organization more closely with the rest of our commercial organization to ensure we maximize the growth opportunities we continue to see in the clinical market. This new aligned structure will sharpen our focus and strengthen our support for our clinical customers.
We also reviewed the broader organization to reduce management spans and layers. Importantly, I want to reiterate that none of our key R&D platform projects were impacted by this reorganization. Turning to discuss our recent performance and where I see the business going from here. Our second quarter was highlighted by the full global commercial rollout of our new SPRQ-Nx chemistry. Access to our SPRQ-Nx beta program was in high demand in Q1, and feedback was highly positive as we approached launch. I am pleased to report that customer enthusiasm for SPRQ-Nx has remained strong since full launch. In fact, in June, over a third of our install base opted into our new instrument software that facilitates usage of SPRQ-Nx, particularly its multi-use capabilities.
As a reminder, SPRQ-Nx provides a significant increase in sequencing throughput per run, and new customers are now able to use each SMRT Cell up to three times. This improves the economics for our customers and enables us to compete for substantially larger projects where competitive economics are crucial to winning. Many of our high throughput customers are currently in the process of validating the new multi-use workflows in their own laboratories, and we expect to see them ramping up SPRQ-Nx usage over the coming months. As a result, we believe SPRQ-Nx will be a significant driver of volume in the second half of the year and beyond. Against the backdrop of the SPRQ-Nx launch, our organization continued to execute on key priorities, including growing the evidence base of scientific validation for our HiFi platform through multiple significant publications.
We believe these speak to the utility of long-read genome sequencing for rare disease diagnostics. In addition, we continue to make progress commercially. We delivered $39 million in second quarter revenue, a step up from Q1. Total revenue was roughly flat year-over-year, driven by growing consumables and new Revio and Vega placements as we commenced the full rollout of SPRQ-Nx chemistry. Another benefit of the SPRQ-Nx economics is that we saw several customers expand their Revio fleet with multi-system orders to take on larger projects and programs. Additionally, we closed and shipped a significant order for several Revio systems to a new population scale customer that we expect to be in sequencing in the third quarter. Looking closer at our consumables performance in the quarter, total consumable revenue for the quarter was $20.1 million compared to $18.9 million the prior year period.
We continue to see strong adoption in the clinical market as shipments to clinical customers grew 67% year-over-year and represented a mid-teens percentage of total consumables shipments. We expect clinical shipments to continue growing as customers move to full commercialization mode across our install base. However, we now expect consumables pull-through for the full year to be $200,000-$225,000 per Revio system due to the pace of demand we are experiencing today. The narrower range reflects the timing of customer purchases, as several accounts that received large Q1 shipments are now working through existing inventory while evaluating the multi-use feature. As we continue to roll out the SPRQ-Nx transition into late 2026 and 2027, we anticipate this range increasing.
We expect to see the first wave of Spark Next consumables reorders in the coming months as accounts work through their inventory. Long term, we expect improved cost per genome economics should support higher utilization. Turning to instruments, we sold 20 Revio systems in the quarter. As I previously indicated, we had several multi-unit Revio shipments this quarter. These include a single new-to-PacBio customer as well as two standing PacBio customers that were looking to further expand their Revio production fleets, which we believe is a testament to the appeal of Revio technology and Spark Next economics to both new and existing customers. These deals, coupled with the Basecamp opportunity we announced in Q1, signal our entry into larger population level genomic studies, which have been unlocked with Spark Next.
We are now seeing specific clinical customers exit R&D mode and move into more routine production sequencing with our HiFi technology. Overall, 60% of Revio placements in Q2 were to new customers, and 45% of Revio placements in Q2 were sold as a part of multi-instrument purchase orders. Cumulative Revio shipments stand at 366 systems. On Vega, we sold 26 Vegas in the second quarter compared to 38 in the prior year period. Customer conversations remain constructive, but funding uncertainty in the U.S. continues to constrain new orders. There are two observations that speak to our continued conviction on Vega, despite these headwinds. Vega ASP has returned to normalized levels, demonstrating that we can drive demand and capture the Vega system's full value in the market without the promotional pricing offered in Q1.
U.S. Public Health Labs, a segment we've deliberately built out, purchased Vega instruments this quarter, and we expect more consistent utilization from these accounts as they ramp. Overall, 81% of Vega shipments in Q2 went to new customers. Cumulative Vega shipments stand at 200 systems. Regionally, EMEA continued to grow, and we expect it will remain our fastest growing region in 2026. Americas revenue declined on academic and government funding constraints, while Asia Pacific consumables also declined as customers worked through existing Spark inventory in preparation for the Spark Next transition. What's encouraging is the reception to Spark Next. Customers across the region are actively evaluating it ahead of stepping up to volume purchases, and we expect that evaluation activity to convert into more routine ordering as the year progresses. As a reminder, Spark Next's core advantage is reusing SMRT Cells multiple times.
Per genome, U.S. list price drops to $345 per 20x HiFi human genome. A 30% reduction versus our previous Spark chemistry, achieved without compromising the accuracy or comprehensiveness that makes HiFi valuable. Expanded methylation detection and advances in DeepConsensus, our AI-powered consensus algorithm developed with Google, further improves accuracy, run performance, and the biological information generated from each read. Spark Next has changed the map for high throughput Revio customers who have been waiting for long-read sequencing to become economically viable at scale, and feedback has been overwhelmingly positive. In the first full month of full commercial rollout, customers have found that HiFi yield is near identical across the first two uses, with a slight decline on the third. In June, over a third of our install base opted into our new software that facilitates usage of Spark Next.
As these customers continue these evaluations, we expect to see an expansion of SPRQ-Nx usage, which will in turn enable more throughput and expand gross margins. We anticipate over half of our install base will have adopted SPRQ-Nx software by the end of the third quarter, and the vast majority to have opted in by year-end. We are also excited to report that we will launch the SPRQ-Nx chemistry on the Vega system later in August. This chemistry will enable higher throughput of up to 90 gigabases per run and lower the DNA input requirements, harmonizing the SPRQ-Nx chemistry across both instruments for consistency of data quality and operations. Turning to the growing validation of our differentiated technology, two recent publications reinforced that HiFi long-read sequencing delivers better, more comprehensive results than the existing standard of care, which typically requires a multi-test process.
The scientific validation strengthens our conviction that we can shift the standard of care paradigm entirely, benefiting patients and providers alike. On June 13th, The New England Journal of Medicine published an article called "Clinical Long-Read Genome Sequencing for Rare Disease Diagnostics" by Bitter et al, which is one of the strongest pieces of evidence for a thesis on the value of long-read sequencing, especially in the clinical setting. Overall, the results were compelling. Concordance between long-read genome sequencing and standard of care was 96.4%. Long-read improved or refined diagnoses in 3.4% of cases, while standard of care only caught variants that long-reads missed in 0.2% of cases. The publication demonstrates that HiFi long-read sequencing is a clinically effective first-tier diagnostic test that improves diagnostic yield while also simplifying the laboratory workflow, reducing turnaround time, and enhancing the overall economics of rare disease diagnostics.
Hundreds of millions of people globally have rare disease, and most of them spend years seeing specialists and being submitted to testing with little resolution to their issues. We believe a publication of this caliber in The New England Journal of Medicine also carries real weight with payers and health systems. It's the kind of evidence that accelerates the transition away from legacy diagnostic workflows to us. A second article was published in Nature Genetics entitled "Near Perfect Genome Sequencing in Medical Genetics" by Sabbah et al. In the article, the authors propose that long-read genome sequencing should be considered as one pillar of a broader technological convergence encompassing diploid genome assembly, pangenome references, and AI-driven variant interpretation turned near-perfect genome sequencing.
They also highlighted the potential that near-perfect genome sequencing across postnatal, prenatal, and oncological settings, while also outlining a staged implementation roadmap toward this one test paradigm. Like The New England Journal of Medicine article, this article similarly supports the move to the one test paradigm given the diagnostic completeness of long-read sequencing technology like HiFi. Beyond rare diseases, we also announced a preprint from the HiFi Solves Sub-fertility Consortium in Asia Pacific, which marks the first major study from that group. Subfertility affects around one in six couples globally, and yet the genetic evaluation most couples receive today is fragmented. Multiple sequential tests often require months or years of evaluation that frequently result in no definitive explanation. The data demonstrates that HiFi whole genome sequencing can provide a complete view of reproductive genetics in a single workflow, representing another long-term clinical opportunity for us.
Additionally, our collaboration to run samples for Basecamp Research has been going very well. Samples are in-house, and we are sequencing and delivering hundreds of samples to Basecamp each week. We expect Basecamp to contribute more meaningfully in 2027 when the majority of the samples will be processed. I'll now turn the call over to Jim. Jim?
Thank you, Mark. I will discuss non-GAAP results, which include non-cash stock-based compensation expenses. I encourage you to review the reconciliation of GAAP to non-GAAP financial measures in our earnings press release. Unless otherwise noted, all growth rates are year-over-year. We reported total revenue of $39 million in the second quarter of 2026, compared to $39.8 million in the second quarter of 2025. Instrument revenue in the second quarter was $12.8 million, a decrease of 9% from $14.2 million in the second quarter of 2025, primarily reflecting a lower average selling price driven by customer mix, including lower-priced strategic Revio placements to key accounts and fewer Vega system shipments as academic and government funding constraints continued to pressure capital purchases.
We sold 20 Revio systems, up from 15 in the prior year, and 26 Vega systems, down from 38, ending the quarter with cumulative shipments of 366 Revio systems and 200 Vega systems. Turning to consumables. Revenue of $20.1 million in the second quarter increased 6% from $18.9 million in the second quarter of 2025, with annualized Revio pull-through per system at approximately $202,000. Consumables revenue increased primarily due to the growth in the installed base and continued utilization of Revio systems, particularly among clinical customers. Growth was partially offset as customers worked through existing inventory and completed SPRQ-Nx workflow validation prior to the broader adoption.
Finally, service and other revenue was $6.1 million in the second quarter compared to $6.7 million in the second quarter of 2025, reflecting continued growth in Revio service contracts as our installed base expanded, offset by lower revenue as we completed a population sequencing program. From a regional perspective, America's revenue of $17.6 million was down slightly compared to the second quarter of 2025, as ongoing NIH and broader academic funding uncertainty continued to weigh on capital purchasing decisions. Clinical and commercial customer activity remained resilient, and we continued expanding our Vega installed base within public health laboratories. For Asia Pacific, revenue of $7 million decreased 45% compared to the second quarter of 2025, primarily reflecting the conclusion of a significant population sequencing program, continued academic and government funding headwinds, and the lower consumables demand as customers completed SPRQ-Nx workflow validation and worked through existing reagent inventory.
EMEA revenue of $14.4 million increased 52% compared to the second quarter of 2025, reflecting continued clinical adoption as hospitals and clinical customers transitioned from pilot programs into routine production, together with growing demand for the Vega platform and a significant strategic multi-system Revio placement supporting a large-scale national genomics initiative. Moving down the P&L, second quarter non-GAAP gross profit of $13.9 million represented a non-GAAP gross margin of 36%, compared to a non-GAAP gross profit of $15.2 million or a gross margin of 38% in the second quarter of 2025. Non-GAAP gross margin declined primarily due to previously discussed compute cost inflation and lower manufacturing volumes. In addition, gross margin was impacted by $1.1 million in costs associated with transitioning Vega manufacturing in-house from our contract manufacturer. These transition costs are expected to conclude by the end of 2026.
Separately, cash outflows were higher due to strategic purchases of memory components to support future production. Importantly, these purchases are largely timing related, and we now expect to have sufficient memory to support operations through the end of 2026. Non-GAAP operating expenses were $56.1 million in the second quarter of 2026, a 3% decrease from $58.1 million in the second quarter of 2025. The year-over-year decline reflects continued expense discipline across the organization while maintaining investment in our highest strategic priorities. Operating expenses in the second quarter included $8.6 million of non-cash share-based compensation, compared to $11 million in the prior year period. Regarding headcount, we ended the quarter with 492 employees, compared to 485 at the end of 2025 and 491 at the end of the second quarter of 2025. As Mark discussed, we recently initiated a restructuring designed to further align our cost structure with our strategic priorities.
This action is expected to reduce our workforce by approximately 40 employees and lower our ongoing operating expense base while preserving investment in our highest priority growth initiatives. Non-GAAP net loss was $41.9 million, representing $0.14 per share in the second quarter of 2026, compared to a non-GAAP net loss of $40 million, representing $0.13 per share in the second quarter of 2025. We ended the second quarter with approximately $236.9 million in unrestricted cash equivalents and investments, compared with $279.5 million at December 31st, 2025. Turning to our full year outlook, given the dynamics that Mark cited, we are lowering our revenue expectations for 2026 to $155 million-$165 million. Our revised outlook assumes consumables will remain the driver of growth, supported by continued utilization from clinical customers and the expanding of Revio and Vega installed base.
At the same time, we expect SPRQ-Nx adoption to build progressively through the second half as customers complete workflow validation and transition existing reagent inventories. We continue to assume no meaningful recovery in academic and government funding, particularly in the Americas, and a more gradual recovery in China than we had previously anticipated. We now expect non-GAAP gross margin to be in the range of 35%-37% for 2026. This revised outlook reflects temporary Vega manufacturing transition costs of approximately $2.5 million, elevated compute and memory costs, a more gradual SPRQ-Nx adoption curve, and the margin impact of lower priced strategic Revio placements.
Turning to our cash outlook, we expect to end the year with approximately $175 million-$185 million in cash, reflecting our updated revenue outlook, continued investments in SPRQ-Nx, the temporary manufacturing costs, and working capital impacts we discussed today, and the cost reduction initiatives Mark outlined earlier. Non-GAAP operating expenses are expected to be in the range of $215 million-$220 million, a reduction of $5 million from the range we guided in Q1, and down from 2025 levels. Looking ahead, we expect cash burn to step down meaningfully in 2027. In addition to the benefits of our restructuring, which we expect to reduce compensation and related expenses by approximately $15 million-$20 million next year, we expect to realize approximately $15 million-$20 million of additional annual savings as we move past development spending on our high throughput platform.
While these actions significantly improve our cash profile, our outlook also reflects the continued impact of elevated compute costs and a more gradual gross margin improvement than we previously anticipated. As a result, we now expect to achieve cash flow breakeven in 2028 compared to our prior expectation of the end of 2027. Based on our current operating plan, we believe our existing cash resources provide sufficient flexibility to execute our strategic priorities, support the commercialization of our new high throughput platform, and fund the business through cash flow breakeven. I will now turn the call back to Mark for closing remarks.
Thanks, Jim. I'm energized about this next chapter for PacBio. The catalysts we've built toward, including SMRT Next's full rollout, expanding clinical adoption, and our entry into population scale genomics are now converging. My focus as CEO is straightforward. Scale and strive in growth, sharpen our execution, and run a leaner, more focused organization built around our highest conviction growth drivers. I've spent five years in this business, and I understand both its potential and what it takes to realize it. I'm confident in our team, our technology, and our path forward. With that, we'll open the line. Jim and I are available for questions.
We will now begin the question and answer session. Again, to ask a question, you may press star then one on your telephone keypad. If you're using a speakerphone, please pick up your handset before pressing the keys. To withdraw a question, please press star then two. On today's call, we ask that you please limit yourself to only one question during Q&A. If you have additional questions, you may rejoin the queue. With that, we will pause just momentarily to assemble our roster. Our first question here will come from Kyle Mikson with Canaccord Genuity. Please go ahead.
Hey, guys. Thanks for the questions. Nice quarter. Christian Henry, it's great working with you these past several years. There's been the highs and the lows, but it's been overall a really impressive job. Mark Van Oene, congrats on the role. It's going to be great to see how things progress going forward, thanks, guys, for everything. Back to the quarter and the questions there. I guess on the Revios and the Vega, interesting to see how many are still coming from new customers. I'm just curious how many are clinical customers? It would be interesting to see if most of these new customers are clinical in nature and how that's kind of looking and shaping going forward. Thanks.
Yeah. Thanks, Kyle Mikson. It's going to be fun working with you as well. It's really my pleasure. I just want to start, just a quick thank you again to Christian Henry and to recognize his contributions to PacBio. His industry knowledge and experience really has transformed PacBio. We've got a portfolio of products. We've got the commercial scale now, workflows and service clinical markets. Really, I'll just be building off of that foundation, and he's going to continue to be a great partner to me as he becomes a member of the board, or stays a member of the board and advises me through this transition. You're speaking specifically about the Revio and Vegas, and maybe I'll start with Revio because it was a good rebound for the Revio. As you can see, we shipped 20 Revios this quarter.
The majority of those to new customers and some multi-system placements, which I think is a really important part of the SMRT Next thesis, Kyle Mikson, to make sure that that economic is driving scaling of existing customers as well as bringing in new customers. In terms of the clinical adoption, the majority of those Revios are going to clinical accounts. We continue to see the momentum in the business there, not just on the growth in consumables, but on the instrument platform. Likewise, in the Vega, we had a smaller number than last year, but I think consistent with last quarter's overall Vega units. The majority of these are to brand new customers to PacBio, which, again, that was the idea with the Vega platform launch, was decentralize the HiFi sequencing, expose more of the globe to our technology.
We continue to do that, and again, Vega is predominantly still smaller targeted applications in terms of applications. I think what we noted there is the health labs are starting to pick up Vega. We're starting to see some momentum in wastewater testing and your non-traditional uses of HiFi genome for higher throughput whole genome type applications. Really encouraged by the Vega new customer demand as well as the clinical and public health lab adoption of it.
Our next question will come from Subbu Nambi with Guggenheim. Please go ahead.
Hey, guys, this is Thomas on for Subbu. Thanks for taking our question. On Revio, you said you placed some boxes to customers doing population scale sequencing, and you gave some comments on the consumables timing. Just thinking about those factors and some clinical accounts, can you just walk us through what you're expecting on pull-through sequentially from here? Just what does the second half look like in terms of third quarter, fourth quarter? Thanks so much.
Yeah. On the population genome opportunity that we mentioned, we'll disclose who that is when the timing's right for that. Expect for some further updates there. On the clinical customer scaling, this is where you start to see the scaling with much faster uptake of the consumables, again, driven with the SPRQ-Nx economics here again. We expect those to start to implement and scale through the back half of this year. In terms of the overall timing of the SPRQ-Nx and consumable scaling, we are going through this transition. You saw we were relatively flat quarter-over-quarter on our consumables revenue. I would expect that to continue through this next quarter and then start scaling as we get through the back end of this year. These SPRQ-Nx customers are optimizing their workflows.
They're getting used to running our SMRT Cells multiple times and hardening the validation of that. I expect this transition to last through this quarter and then start to scale towards the back end of the year.
Our next question will come from Jack Meehan with Operon Research. Please go ahead.
Thanks. Good afternoon, guys. Mark, congrats on the new role. My question's for Jim. I was wondering if it was possible to talk about gross margins for memory. How much of your supply is locked in now for the second half in 2027? Can you talk about what any incremental headwinds could be if the spot pricing holds? Maybe just on the positive side, you've talked about the multi-use SMRT Cells potentially improving PacBio gross margins. When do you think that's going to start to show up? Thanks.
Sure. Thanks, Jack. First, let's talk about the memory impact and its implications for this quarter and going on. From the standpoint of supply, we are supplied through the end of 2026 based on our current forecast. We have memory coverage, GPU coverage through then. We'll probably enter the market to start purchasing more memory tail end of this year. As we're looking, part of the reason we've adjusted our gross margin guidance down to 35%-37%, is we do expect the memory impact to persist through the rest of this year. We don't have good visibility into 2027 yet. That's part of what drove some of the actions that Mark talked about in the restructuring. Number two is the other piece that's actually impacting our margins for the rest of this year is the transition cost of the Vega.
One of the things we're really trying to do is cut costs in the long term as we insource manufacturing and bring down a number of suppliers. Part of that transition, we're incurring some unanticipated costs. However, it's allowing us to accelerate that transition to Vega, to in-house manufacturing. That's something we are doing to help us look a lot better moving into 2027. Then the third part of your question is, as Mark mentioned, we do expect the SPRQ-Nx ramp to increase more in the latter half of the second half of the year. That will be offsetting some of those persistent memory costs and those transition costs. We're excited to get the transition behind us. I think we're excited to see memory stabilize.
I don't think we're going to necessarily see a decrease in memory, but I think one of the things we've been impacted by is the fluctuations in spot markets and how that's impacting or impacting our supply chain. That's part of the reason we have some of the unanticipated impacts in the latter half of the year. I think some of the early indicators are, is that's starting to stabilize. Thank you.
Our next question will come from Mason Carrico with Stephens. Please go ahead.
Hey, guys. Thanks for taking the question here. On SPRQ-Nx, I guess could you just talk about the early signals and signs, I guess, that you're seeing from customers on whether that 30%-40% cost reduction is expanding sample volumes to more than offset that pricing discount and how we should be thinking about maybe the sequential pacing of that playing out as we get into the back half of the year?
Yeah. Thanks, Mason, for the question. This SPRQ-Nx launch is critical for us to establish both ourselves in these larger scale programs, which we're seeing the indication of with some of these multisystem Revio deals. But also for that gross margin expansion that we talk about. The 30% price decrease, I do expect us to overcome here as we work through the growth in the back half of this year. I think the timing is relatively short term. We mentioned that we've already seen a third of our customers upgrade the software, to enable the SPRQ-Nx, and so the demand is there. We have seen in Asia Pac the drop in consumables in the second quarter was them burning down their SPRQ inventory and getting ready to take on the shipments of SPRQ-Nx at scale.
The early indicators are there and the excitement is there, as well as the opportunity for involvement in some of these larger projects. We look for that gap to be closed as we work through this quarter and then exit the back end of this year.
Our next question will come from Dan Brennan with TD Cowen. Please go ahead.
Hi, Pradeep on for Dan. This transition phase with the SPRQ-Nx chemistry on Revio with the existing inventory and the validation phase, do you similarly expect that with Vega consumables a few months after launch or not so much because that's a different base of customers? Thank you.
Yeah. I don't expect the same dynamic with Vega, mostly because Vega utilization is less than that of the Revio, and so I don't think you'll see the same impact on utilization with Vega. I think what you'll see with Vega is an opportunity for the SPRQ-Nx to expand the application set that Vega's used for. In this launch, we're increasing the throughput of Vega to be able to deliver 90 gigabases of yield versus the 60 with the on-market version of Vega. We do think that that increase in data is going to enable people to start thinking about larger panels of genes, larger amplicon sets, the occasional whole genome, whether that's human or non-human genome.
More than anything, I think, the SPRQ-Nx on Vega with the higher throughput and the lower DNA input requirements is going to open up the applications that we see on that and drive utilization upwards.
Our next question will come from David Westenberg with Piper Sandler. Please go ahead.
Hi. Thanks. This is Sky on for Dave. Thanks for the question. Maybe just more generally, as the industry is shifting now towards multiomics, can you talk about the advantage of PacBio's long-read technology? Kind of what are you seeing from your biopharma partners? What are they looking for, and where are the demands there? Thanks.
Yeah. This is where I really do believe that we are most differentiated. We have the most comprehensive clinical genome or whole genome that lets us look at, if you think about multiomics in the sense of different variant classes. We're seeing a lot of interest in the repeat expansions and the structural variation that you see and then the diploid genomics that lead to the publications like the near-perfect genome paper. The methylation is starting to expand in knowledge and the reference sets around that, and the methylation signatures are starting to expand the desire for the methylation that comes with our genome analysis. In the multiomics sense of the DNA, and we're starting to see a lot of progress, including that in chromatin architecture.
In the RNA world, the desire for isoforms and looking at the impact of isoforms across development and conditions is continuing to increase, which is driving the transcriptomics field into more of a transcriptomics rather than gene expression field. The combination of DNA and RNA is working really well for us. When I talk about how important it is for us to drive our data into better datasets and then model training in the future, it is the comprehensiveness and the multiomics nature of the data that makes this so attractive to people. How can they look at something that's going to be future-proofed so that they can go there and use our data for AI model development, as we've seen with the Basecamp deal and work there.
Comprehensiveness and quality in multiomics is only becoming more and more prevalent in the conversations that we have with biopharma and/or just the biology research community.
Our next question will come from Tycho Peterson with Jefferies. Please go ahead.
Hey, team. This is Lauren on for Tycho. Mark, congrats on the new role. Thanks for taking the question. Mine is around the guidance. You lowered it since last quarter, but that's despite having the SPRQ-Nx launch on both systems now, ramp in the back half of the year, new population scale customer, accelerating Revio placements. Could you just talk about what's not showing up in these positive signals that resulted the confidence to come down? Thanks.
Yeah. Thanks for the question. I do believe that the guidance that we provided, the $155 million-$165 million, does reflect the confidence in our ability to execute. While we do see the traction and a lot of positivity, this is in the context of the SPRQ-Nx transition. I think, because of that, I think it's appropriate that we have this guidance range on the revenue side. The impact on the cost of compute that Jim was talking about is real. While we're looking at different ways to mitigate that, and we've done some pre-purchasing of that, I do think that the guidance on the gross margin is also better reflected with just the uncertainty that we have and some of the real headwinds that exist there.
To me, it's the SPRQ-Nx transition headwinds and the cost of compute headwinds that we just want to make sure that we're properly accounting for. Because of that, we've ended up lowering or extending, sorry, our expectations on cash flow break even into 2028. I think we take a really balanced view given the backdrop of what we're working through over the back half of this year.
Again, if you have a question or follow-up, you may press star then one to join the queue. Our next question will come from Luke Sergott with Barclays. Please go ahead.
Great. Thanks, Mark. Congratulations. Long time coming. Christian, I hope we still see you at AGBT, perennial on the dance floor out there. I guess just on the commercial reorg, what spurred the changes, and what's the new look going to be like? I understand that you want to be more focused and agile for the clinical customers, you guys have AI customers now, you have PacBio customers. Just what other investments are you going to need to make, or what's that structure going to look like?
Thanks, Luke, I'm sure we'll play some beer pong. The clinical team is doing really well, it's really leveraging what we're seeing in Europe and the clinical traction we're getting in Europe, how can I more effectively take that out in a really positive combined motion into the rest of the world. The restructure was a lot around the marketing organization to really focus them on the clinical workflows, the clinical marketing, how we're going to drive the understanding of the usefulness of HiFi, even around that clinical market. It is really alignment of marketing and sales motions and sales enabling towards that clinical opportunity that we're really starting to see the early stages of success in Europe and then expanding that. Don't expect a massive change.
We're going to continue to always support the plant animal and the research community if the research budgets start to unlock here. It's really just the education and awareness that's required right now for us to focus on that clinical opportunity. When you talk about biopharma and data strategies, those are large, lumpier deals that are handled more in a business development or corporate development piece of the company, I don't see that as a major distraction. I really think it's just a united force making sure that we're stepping into this clinical opportunity that I see ahead for us.
This will conclude our question and answer session in addition to today's call. Thank you all for attending and participating in today's presentation. You may now disconnect your lines, have a great day.
Investor releaseQuarter not tagged2026-08-04Pacific Biosciences of California, Inc. Q2 2026 Earnings Call Summary
Moby
Pacific Biosciences of California, Inc. Q2 2026 Earnings Call Summary
Our analysts just identified a stock with the potential to be the next Nvidia. Tell us how you invest and we'll show you why it's our #1 pick. Tap here. Mark Van Oene succeeded Christian Henry as CEO, signaling a shift toward scaling clinical engagement strategies globally following successful execution in the EMEA region. Initiated a targeted reorganization to integrate marketing more closely with commercial operations, focusing on clinical market growth while reducing management layers. Launched SPRQ-Nx chemistry globally, which reduces the cost per human genome by 30% to $345 by allowing SMRT Cells to be reused up to three times. Performance was driven by a 67% year-over-year increase in consumable shipments to clinical customers, which now represent a mid-teens percentage of total shipments. Revio instrument placements rebounded to 20 units, supported by multi-system orders from customers expanding fleets for larger population-scale genomic studies. Vega system demand remains constrained by U.S. academic and government funding uncertainty, though ASPs have normalized following the conclusion of Q1 promotional pricing. Management attributes the flat year-over-year revenue to customers working through existing inventory while validating the new multi-use SPRQ-Nx workflows. Lowered 2026 revenue guidance to $155 million to $165 million, assuming a more gradual recovery in China and persistent funding constraints in the Americas. Extended the timeline for cash flow breakeven to 2028, citing elevated compute and memory costs and a slower gross margin improvement trajectory. Expects SPRQ-Nx to be a significant volume driver in the second half of 2026 as over half the installed base is projected to adopt the new software by the end of Q3. Anticipates 2027 cash burn to step down meaningfully due to $15 million to $20 million in restructuring savings, plus an additional $15 million to $20 million in savings from the conclusion of development spending on the high-throughput platform. Plans to launch SPRQ-Nx chemistry on the Vega system in August 2026 to harmonize throughput and DNA input requirements across the instrument portfolio. Restructuring involves a workforce reduction of approximately 40 employees to align the cost structure with clinical growth priorities. Gross margins were impacted by $1.1 million in temporary costs related to transitioning Vega manufac…Read full documentShow less
Our analysts just identified a stock with the potential to be the next Nvidia. Tell us how you invest and we'll show you why it's our #1 pick. Tap here. Mark Van Oene succeeded Christian Henry as CEO, signaling a shift toward scaling clinical engagement strategies globally following successful execution in the EMEA region. Initiated a targeted reorganization to integrate marketing more closely with commercial operations, focusing on clinical market growth while reducing management layers. Launched SPRQ-Nx chemistry globally, which reduces the cost per human genome by 30% to $345 by allowing SMRT Cells to be reused up to three times. Performance was driven by a 67% year-over-year increase in consumable shipments to clinical customers, which now represent a mid-teens percentage of total shipments. Revio instrument placements rebounded to 20 units, supported by multi-system orders from customers expanding fleets for larger population-scale genomic studies. Vega system demand remains constrained by U.S. academic and government funding uncertainty, though ASPs have normalized following the conclusion of Q1 promotional pricing. Management attributes the flat year-over-year revenue to customers working through existing inventory while validating the new multi-use SPRQ-Nx workflows. Lowered 2026 revenue guidance to $155 million to $165 million, assuming a more gradual recovery in China and persistent funding constraints in the Americas. Extended the timeline for cash flow breakeven to 2028, citing elevated compute and memory costs and a slower gross margin improvement trajectory. Expects SPRQ-Nx to be a significant volume driver in the second half of 2026 as over half the installed base is projected to adopt the new software by the end of Q3. Anticipates 2027 cash burn to step down meaningfully due to $15 million to $20 million in restructuring savings, plus an additional $15 million to $20 million in savings from the conclusion of development spending on the high-throughput platform. Plans to launch SPRQ-Nx chemistry on the Vega system in August 2026 to harmonize throughput and DNA input requirements across the instrument portfolio. Restructuring involves a workforce reduction of approximately 40 employees to align the cost structure with clinical growth priorities. Gross margins were impacted by $1.1 million in temporary costs related to transitioning Vega manufacturing in-house, a process expected to conclude by year-end 2026. Strategic pre-purchasing of memory components has secured supply through the end of 2026, though spot market fluctuations remain a persistent headwind. Revised Revio pull-through guidance to $200,000 to $225,000 per system to reflect the current pace of demand and inventory burn-down during the chemistry transition. One stock. Nvidia-level potential. 30M+ investors trust Moby to find it first. Get the pick. Tap here. Management confirmed the majority of Revio placements are going to clinical accounts, while Vega is successfully attracting new-to-PacBio customers. Public health labs are beginning to adopt Vega for non-traditional applications like wastewater testing and higher-throughput whole genome sequencing. Supply for memory and GPUs is locked in through the end of 2026, but management lacks clear visibility into 2027 pricing dynamics. The 35% to 37% gross margin guidance accounts for persistent compute cost inflation and the temporary costs of insourcing Vega manufacturing. Management expects the 30% price reduction per genome to be offset by increased sample volumes as the technology becomes economically viable for larger projects. Early indicators in Asia-Pacific show customers are actively burning through old inventory to transition to the higher-throughput SPRQ-Nx chemistry. The restructure aims to replicate the EMEA clinical success model globally by uniting marketing and sales motions specifically around clinical workflows. Management clarified that large-scale biopharma and AI data deals will continue to be managed through business development, separate from the clinical sales focus.
Investor releaseQuarter not tagged2026-07-15PacBio to Report Second Quarter 2026 Financial Results on August 5, 2026
GlobeNewswire
PacBio to Report Second Quarter 2026 Financial Results on August 5, 2026
MENLO PARK, Calif., July 15, 2026 (GLOBE NEWSWIRE) -- PacBio (NASDAQ: PACB) announced today that it will hold its quarterly conference call to discuss its second quarter 2026 financial results on Wednesday, August 5, 2026, at 4:30 p.m. Eastern Time (1:30 p.m. Pacific Time). The call will be webcast and may be accessed on PacBio’s website at https://investor.pacificbiosciences.com/. Date: Wednesday, August 5, 2026, at 4:30 p.m. ET (1:30 p.m. PT) Listen live via internet or replay: https://investor.pacificbiosciences.com/ Toll-free: 1-888-349-0136 International: 1-412-317-0459 About PacBio PacBio (NASDAQ: PACB) is a premier life science technology company that designs, develops, and manufactures advanced sequencing solutions to help scientists and clinical researchers resolve genetically complex problems. Our products and technologies, which include our HiFi long-read sequencing, address solutions across a broad set of research applications including human germline sequencing, plant and animal sciences, infectious disease and microbiology, oncology, and other emerging applications. For more information, please visit www.pacb.com and follow @PacBio. PacBio products are provided for Research Use Only. Not for use in diagnostic procedures. Contacts Investors: [email protected] Media: [email protected]
Investor releaseQuarter not tagged2026-06-02Q1 Earnings Highs And Lows: PacBio (NASDAQ:PACB) Vs The Rest Of The Life Sciences Tools & Services Stocks
StockStory
Q1 Earnings Highs And Lows: PacBio (NASDAQ:PACB) Vs The Rest Of The Life Sciences Tools & Services Stocks
Looking back on life sciences tools & services stocks’ Q1 earnings, we examine this quarter’s best and worst performers, including PacBio (NASDAQ:PACB) and its peers. The life sciences tools and services sector supports biotech and pharmaceutical R&D and commercialization by providing lab equipment, data analytics, and clinical trial services. These companies benefit from recurring revenue and high margins on specialized products. Looking ahead, the sector is supported by tailwinds like advancements in genomics, personalized medicine, and the use of AI in drug discovery. However, the persistent challenge is dependence on the R&D budgets of large pharmaceutical companies and the volatility of smaller biotech firms. Future headwinds include uncertain research funding and pricing pressures from cost-conscious customers. The 21 life sciences tools & services stocks we track reported a satisfactory Q1. As a group, revenues beat analysts’ consensus estimates by 1.2% while next quarter’s revenue guidance was in line. Luckily, life sciences tools & services stocks have performed well with share prices up 10.2% on average since the latest earnings results. Pioneering what scientists call "HiFi long-read sequencing," recognized as Nature Methods' method of the year for 2022, Pacific Biosciences (NASDAQ:PACB) develops advanced DNA sequencing systems that enable scientists and researchers to analyze genomes with unprecedented accuracy and completeness. PacBio reported revenues of $37.18 million, flat year on year. This print fell short of analysts’ expectations by 7.1%. Overall, it was a softer quarter for the company with a significant miss of analysts’ revenue estimates. “We continue to see increasing clinical adoption of HiFi which contributed to another record quarter for consumable revenue. However, instrument revenue, particularly Vega, was lower than we had expected," said Christian Henry, President and Chief Executive Officer. PacBio delivered the weakest performance against analyst estimates of the whole group. Unsurprisingly, the stock is down 6.4% since reporting and currently trades at $1.55. Read our full report on PacBio here, it’s free. Founded in 1923 and serving as a critical link in the pharmaceutical supply chain, West Pharmaceutical Services (NYSE:WST) manufactures specialized packaging, containment systems, and delivery devices for injectable drugs…Read full documentShow less
Looking back on life sciences tools & services stocks’ Q1 earnings, we examine this quarter’s best and worst performers, including PacBio (NASDAQ:PACB) and its peers. The life sciences tools and services sector supports biotech and pharmaceutical R&D and commercialization by providing lab equipment, data analytics, and clinical trial services. These companies benefit from recurring revenue and high margins on specialized products. Looking ahead, the sector is supported by tailwinds like advancements in genomics, personalized medicine, and the use of AI in drug discovery. However, the persistent challenge is dependence on the R&D budgets of large pharmaceutical companies and the volatility of smaller biotech firms. Future headwinds include uncertain research funding and pricing pressures from cost-conscious customers. The 21 life sciences tools & services stocks we track reported a satisfactory Q1. As a group, revenues beat analysts’ consensus estimates by 1.2% while next quarter’s revenue guidance was in line. Luckily, life sciences tools & services stocks have performed well with share prices up 10.2% on average since the latest earnings results. Pioneering what scientists call "HiFi long-read sequencing," recognized as Nature Methods' method of the year for 2022, Pacific Biosciences (NASDAQ:PACB) develops advanced DNA sequencing systems that enable scientists and researchers to analyze genomes with unprecedented accuracy and completeness. PacBio reported revenues of $37.18 million, flat year on year. This print fell short of analysts’ expectations by 7.1%. Overall, it was a softer quarter for the company with a significant miss of analysts’ revenue estimates. “We continue to see increasing clinical adoption of HiFi which contributed to another record quarter for consumable revenue. However, instrument revenue, particularly Vega, was lower than we had expected," said Christian Henry, President and Chief Executive Officer. PacBio delivered the weakest performance against analyst estimates of the whole group. Unsurprisingly, the stock is down 6.4% since reporting and currently trades at $1.55. Read our full report on PacBio here, it’s free. Founded in 1923 and serving as a critical link in the pharmaceutical supply chain, West Pharmaceutical Services (NYSE:WST) manufactures specialized packaging, containment systems, and delivery devices for injectable drugs and healthcare products. West Pharmaceutical Services reported revenues of $844.9 million, up 21% year on year, outperforming analysts’ expectations by 8.4%. The business had a stunning quarter with a beat of analysts’ EPS and revenue estimates. West Pharmaceutical Services achieved the biggest analyst estimate beat among its peers. The market seems happy with the results as the stock is up 18% since reporting. It currently trades at $323.85. Is now the time to buy West Pharmaceutical Services? Access our full analysis of the earnings results here, it’s free. Serving as the guardian of some of medicine's most valuable materials, Azenta (NASDAQ:AZTA) provides biological sample management, storage, and genomic services that help pharmaceutical and biotechnology companies preserve and analyze critical research materials. Azenta reported revenues of $144.8 million, up 1% year on year, falling short of analysts’ expectations by 2.5%. It was a disappointing quarter as it posted a significant miss of analysts’ revenue and EPS estimates. As expected, the stock is down 5.8% since the results and currently trades at $23.19. Read our full analysis of Azenta’s results here. With roots dating back to the pioneering days of nuclear magnetic resonance technology, Bruker (NASDAQ:BRKR) develops and manufactures high-performance scientific instruments that enable researchers and industrial analysts to explore materials at microscopic, molecular, and cellular levels. Bruker reported revenues of $823.4 million, up 2.7% year on year. This number beat analysts’ expectations by 3.4%. Overall, it was a very strong quarter as it also put up a beat of analysts’ EPS and revenue estimates. The stock is up 56% since reporting and currently trades at $59.30. Read our full, actionable report on Bruker here, it’s free. Pioneering the ability to read the human genome at unprecedented speed and affordability, Illumina (NASDAQ:ILMN) develops and sells advanced DNA sequencing and microarray technologies that allow researchers and clinicians to analyze genetic variations and functions. Illumina reported revenues of $1.09 billion, up 4.8% year on year. This result topped analysts’ expectations by 1.8%. It was a strong quarter as it also produced a solid beat of analysts’ full-year EPS guidance estimates. The stock is up 29.1% since reporting and currently trades at $163.68. Read our full, actionable report on Illumina here, it’s free. Late in 2025 into early 2026, there was hand-wringing around artificial intelligence. For software companies, the fear was that AI would erode pricing power and compress margins as new tools made it easier to replicate what once required expensive enterprise platforms. Crypto investors had their own version of the same anxiety: if AI agents could trade, allocate capital, and manage wallets autonomously, what exactly was the long-term value of today’s crypto infrastructure? These concerns triggered a noticeable rotation away from these sectors and into safer havens. But markets rarely dwell on one narrative for long. Spring 2026 came, and the focus shifted abruptly from technological disruption to geopolitical risk. The US’ conflict with Iran became the dominant driver of market psychology, and when geopolitics takes center stage, the script changes quickly. Investors stop debating growth rates and start worrying about oil supply, inflation, and global stability. Want to invest in winners with rock-solid fundamentals? Check out our Top 5 Growth Stocks and add them to your watchlist. These companies are poised for growth regardless of the political or macroeconomic climate. StockStory’s analyst team — all seasoned professional investors — uses quantitative analysis and automation to deliver market-beating insights faster and with higher quality.

