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FENC

FennecA
Nasdaq / Pharmaceuticals, Biotechnology & Life Sciences
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2026-06-11
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2026-05-23
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Earnings documents stored for FENC.

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Investor releaseQuarter not tagged2026-05-23

Adherex Technologies’ PEDMARK Push Targets Larger AYA Market After Record Quarter

MarketBeat

Interested in Adherex Technologies Inc.? Here are five stocks we like better. Fennec Pharmaceuticals said PEDMARK is seeing stronger commercial traction, with first-quarter 2026 revenue reaching a record $15.1 million as the company expands its sales force and targets more than 5,400 U.S. treatment sites. The company is focusing on the adolescent and young adult (AYA) market, which management says is about 10 times larger than the pediatric market, and is also promoting home administration through its Fennec HEARS program. Fennec highlighted international expansion and patent protection, including a European partnership with Norgine, plans for a Japan deal, and a U.S. settlement that keeps a generic challenger off the market until 2033. Fennec Pharmaceuticals (NASDAQ:FENC) executives outlined the company’s commercial strategy for PEDMARK, its sodium thiosulfate product used to prevent cisplatin-related hearing loss, during a fireside chat at the H.C. Wainwright 4th Annual BioConnect Investor Conference. Ram Selvaraju, managing director and senior healthcare equity research analyst at H.C. Wainwright, introduced the company and said H.C. Wainwright covers Fennec with a buy rating and a 12-month price target of $13 per share. Fennec Chief Executive Officer Jeff Hackman and Chief Financial Officer Robert Andrade discussed PEDMARK’s market opportunity, recent revenue performance, international plans and patent position. → CAVA Group’s Stock Looks Delicious After Strong Earnings Andrade described PEDMARK as “the first and only approved agent for the prevention of hearing loss” associated with cisplatin, a chemotherapy widely used in solid tumors across pediatric, adolescent, young adult and adult patients. He said cisplatin can be highly effective, with overall effectiveness rates of up to 90% depending on tumor type, but may be associated with hearing loss in up to 75% of patients. Andrade said PEDMARK has been studied for more than 30 years and was evaluated in two Phase 3 trials, including one published in the New England Journal of Medicine. He said the trials statistically showed that hearing loss was reduced, or at least cut in half, in the overall patient population. → SpaceX IPO: Opportunity? Or the Ultimate Hype Trade? Hackman said a key commercial task is increasing awareness among oncologists that cisplatin-related hearing loss can be prevented. “The a...

Investor releaseQuarter not tagged2026-05-15

Fennec Pharmaceuticals Inc (FENC) Q1 2026 Earnings Call Highlights: Record Sales Surge and ...

GuruFocus.com

This article first appeared on GuruFocus. Net Product Sales: $15.1 million for Q1 2026, a 73% increase year-over-year from $8.8 million in Q1 2025. Operating Expenses (OpEx): Approximately $14 million for the quarter, with a $6 million year-over-year increase, primarily in SG&A. Cash and Cash Equivalents: $40.1 million as of March 31, 2026, with a $3.3 million increase during the quarter. Operating Cash Flow: $2.3 million for the quarter. Cash OpEx Expectation for 2026: Approximately $50 million, with over 60% in the first half of the year. Positive Cash Flow: Achieved in Q1 2026, with expectations for cash growth in the second half of the year. Warning! GuruFocus has detected 5 Warning Signs with FENC. Is FENC fairly valued? Test your thesis with our free DCF calculator. Release Date: May 14, 2026 For the complete transcript of the earnings call, please refer to the full earnings call transcript. Fennec Pharmaceuticals Inc (NASDAQ:FENC) reported a 73% year-over-year increase in net product sales for the first quarter of 2026, reaching $15.1 million. The company has successfully expanded its commercial team, increasing its reach and frequency in the market, which has contributed to significant growth in new patient enrollments. Fennec HEARS, the company's full-service patient support program, has shown strong performance with a 48% quarter-over-quarter increase in completed infusions. The company is seeing positive early indicators from its Project Ignite initiative, which has expanded its ability to engage healthcare professionals and support adoption. Fennec Pharmaceuticals Inc (NASDAQ:FENC) has announced multiple investigator-initiated studies to evaluate PEDMARK in new patient populations, indicating growing clinical interest and potential for broader adoption. Operating expenses increased by approximately $6 million year-over-year, primarily due to expanded marketing investment and increased commercial headcount. The company does not anticipate receiving the German milestone payment from its partner, Norgine, which could impact expected revenue streams. Despite positive cash flow in the first quarter, Fennec Pharmaceuticals Inc (NASDAQ:FENC) expects the second quarter ending cash to be lower due to collection cycles with customers. The pediatric market is growing at a slower pace compared to the AYA market, which may impact overall growth potential in t...

Investor releaseQuarter not tagged2026-05-15

Fennec Pharmaceuticals Inc. Q1 2026 Earnings Call Summary

Moby

Our analysts just identified a stock with the potential to be the next Nvidia. Tell us how you invest and we'll show you why it's our #1 pick. Tap here. Management attributes the 73% year-over-year revenue growth to the 'Project Ignite' initiative, which optimized sales reach and frequency through a significant headcount expansion. The commercial strategy has pivoted from a narrow focus to a broader target base of over 5,000 prescribers, up from 1,300, specifically targeting the promotionally sensitive Adolescent and Young Adult (AYA) market. Operational improvements in the 'Fennec HEARS' patient support program have driven conversion rates to a benchmark of 80%, effectively translating prescription demand into completed therapy. Strategic positioning is being reinforced by a growing body of clinical evidence, including three new investigator-initiated studies aimed at expanding PEDMARK's utility in adult head, neck, and testicular cancers. The company is utilizing a 'top-down' adoption approach by partnering with major oncology aggregators and GPOs to integrate PEDMARK into electronic medical record (EMR) order sets. Management highlighted a healthy mix of new and existing prescribers, with established accounts showing deeper utilization and increased vials per account as they become more comfortable with the product. Management expects 2026 to be a defining period, with demand in Q2 already tracking to surpass Q1 based on record enrollment levels observed in April. The company anticipates operating income to grow meaningfully in upcoming quarters due to a predominantly fixed cost base and high operating leverage. Financial guidance assumes approximately $50 million in cash operating expenses for 2026, with over 60% of these costs front-loaded in the first half of the year. International growth is expected to ramp as partner Norgine launches PEDMARQSI in nearly double-digit markets throughout 2026, with potential sales-based milestones by year-end. The company is actively exploring business development opportunities to layer additional commercial assets onto its newly expanded sales infrastructure. Management explicitly stated they no longer anticipate receiving a previously expected milestone payment from the German market. The company expects a temporary dip in cash position for Q2 due to collection cycles, though they project returning to positive cash f...

Investor releaseQuarter not tagged2026-05-14

Fennec Pharmaceuticals up 12.6% in U.S. Pre-Market on Q1 Earnings as Pedmark Sales Jump 73%

MT Newswires

Fennec Pharmaceuticals (FRX.TO), up 12.6% in U.S. pre-market trading, Thursday reported a swing to a

Investor releaseQuarter not tagged2026-05-14

Fennec Pharmaceuticals Shares Rise After Earnings and Revenue Beat Forecasts (FENC)

InvestorsHub

Fennec Pharmaceuticals (NASDAQ:FENC) shares climbed more than 3% in premarket trading on Thursday after the company reported first-quarter results that exceeded analyst expectations, supported by strong sales growth for PEDMARK. The company posted adjusted earnings per share of $0.01, outperforming consensus forecasts for a loss of $0.04 per share. Revenue increased 73% year over year to $15.11 million, ahead of analyst estimates of $14.65 million and up from $8.75 million in the same quarter last year. Fennec said the increase in revenue was primarily driven by broader adoption of PEDMARK across existing and new accounts, including growth within the adolescent and young adult patient population. “We are encouraged by our continued quarter-over-quarter growth and strong start to the year,” said Jeff Hackman, chief executive officer of Fennec Pharmaceuticals. “The strategic enhancements we’ve made to our field force are already sharpening our execution and expanding our reach.” Selling and marketing expenses rose to $11.4 million during the quarter, compared with $3.2 million a year earlier, largely reflecting increased spending tied to PEDMARK commercialisation efforts and the expansion of the company’s sales team. Meanwhile, general and administrative expenses declined to $3.2 million from $5.9 million in the prior-year quarter, mainly due to lower legal and professional fees following the conclusion of litigation-related activities. The company said demand for PEDMARK continued to be supported by prescriptions related to three primary tumour categories: testicular cancer, cervical cancer, and head and neck cancers. In April 2026, Fennec announced the launch of an investigator-sponsored study led by the University of Arizona Cancer Center to evaluate PEDMARK in adolescent, young adult and adult patients with head and neck and testicular cancers. Fennec ended the quarter with cash and cash equivalents totaling $40.1 million, compared with $36.8 million at the end of 2025. The company said it expects its current cash reserves, together with anticipated PEDMARK revenue, to be sufficient to support operations under its existing business plan. Fennec Pharmaceuticals stock price

Investor releaseQuarter not tagged2026-05-14

Fennec Pharmaceuticals Reports First Quarter 2026 Financial Results and Provides Business Update

GlobeNewswire

~ Achieved First Quarter 2026 Total Net Revenues of $15.1 Million, Up 73% Year Over Year ~ ~ Field Sales Expansion Showing Early Signs of Positive Results with Record PEDMARK® Demand in April 2026 ~ ~ Initiated Third Institution-Led Clinical Study Evaluating PEDMARK® in Adolescent and Young Adult (AYA) and Adult Patients with Head and Neck and Testicular Cancers ~ ~ Four Abstracts Evaluating PEDMARK® will be Included in the Upcoming 2026 American Society of Clinical Oncology (ASCO) Annual Meeting Program ~ ~ Management to Host Conference Call Today at 8:30 a.m. ET ~ RESEARCH TRIANGLE PARK, N.C., May 14, 2026 (GLOBE NEWSWIRE) -- Fennec Pharmaceuticals Inc. (NASDAQ:FENC; TSX: FRX), a specialty pharmaceutical company, today reported its financial results for the first quarter ended March 31, 2026 and provided a business update. “We are encouraged by our continued quarter-over-quarter growth and strong start to the year. 2026 is a defining period for Fennec, with growing clinical interest in independently evaluating PEDMARK® (sodium thiosulfate injection) across new patient populations and tumor types that reinforces our confidence in its broader potential,” said Jeff Hackman, chief executive officer of Fennec Pharmaceuticals. “At the same time, the strategic enhancements we’ve made to our field force are already sharpening our execution and expanding our reach – in tandem, the positive experiences we’re seeing through our Fennec HEARS® program are translating into meaningful access and strong conversion rates, resulting in more patients being treated. Coupled with our solid financial foundation, we believe we are well-positioned to continue to build momentum and deliver sustained growth throughout 2026.” Business Highlights: Continued Growth Within Key PEDMARK® Accounts: Adoption continues to build across both new and existing accounts, with established prescribers demonstrating growing confidence in PEDMARK®, contributing to deeper utilization and higher vials per account. Demand in the first quarter was driven by prescribing in three core tumor types: testicular, cervical and head and neck cancers, and these remain foundational to Fennec’s commercial opportunity. Additionally, our comprehensive patient services HUB, Fennec HEARS®, continues to be an important contributor to PEDMARK® utilization and HCP adoption. Through ongoing operational refinements, we are...

Investor releaseQuarter not tagged2026-05-14

Adherex Technologies Inc. (FENC) Beats Q1 Earnings and Revenue Estimates

Zacks

Adherex Technologies Inc. (FENC) came out with quarterly earnings of $0.01 per share, beating the Zacks Consensus Estimate of a loss of $0.02 per share. This compares to a loss of $0.04 per share a year ago. These figures are adjusted for non-recurring items. This quarterly report represents an earnings surprise of +157.14%. A quarter ago, it was expected that this company would post earnings of $0.03 per share when it actually produced a loss of $0.11, delivering a surprise of -466.67%. Over the last four quarters, the company has surpassed consensus EPS estimates two times. Adherex Technologies, which belongs to the Zacks Medical - Biomedical and Genetics industry, posted revenues of $15.11 million for the quarter ended March 2026, surpassing the Zacks Consensus Estimate by 8.36%. This compares to year-ago revenues of $8.75 million. The company has topped consensus revenue estimates three times over the last four quarters. The sustainability of the stock's immediate price movement based on the recently-released numbers and future earnings expectations will mostly depend on management's commentary on the earnings call. Adherex Technologies shares have lost about 12.1% since the beginning of the year versus the S&P 500's gain of 8.8%. While Adherex Technologies has underperformed the market so far this year, the question that comes to investors' minds is: what's next for the stock? There are no easy answers to this key question, but one reliable measure that can help investors address this is the company's earnings outlook. Not only does this include current consensus earnings expectations for the coming quarter(s), but also how these expectations have changed lately. Empirical research shows a strong correlation between near-term stock movements and trends in earnings estimate revisions. Investors can track such revisions by themselves or rely on a tried-and-tested rating tool like the Zacks Rank, which has an impressive track record of harnessing the power of earnings estimate revisions. Ahead of this earnings release, the estimate revisions trend for Adherex Technologies was unfavorable. While the magnitude and direction of estimate revisions could change following the company's just-released earnings report, the current status translates into a Zacks Rank #5 (Strong Sell) for the stock. So, the shares are expected to underperform the market in the near f...

Investor releaseQuarter not tagged2026-05-14

Adherex Technologies Q1 Earnings Call Highlights

MarketBeat

Interested in Adherex Technologies Inc.? Here are five stocks we like better. Fennec Pharmaceuticals reported strong Q1 2026 results, with net product sales rising about 73% year over year to $15.1 million and positive operating cash flow. Management said it was the sixth straight quarter of sales growth. The company’s expanded sales force under Project Ignite is starting to pay off, with the target prescriber base growing from roughly 1,300 to more than 5,000. Executives said the broader reach is driving demand from both new and existing prescribers, while the Fennec HEARS support program boosted completed infusions and hit an 80% conversion benchmark for the first time. Management also highlighted growing clinical interest in PEDMARK beyond pediatrics, including investigator-initiated studies in AYA and adult cancer patients and multiple ASCO abstracts. Fennec said its cash position remains strong enough, alongside projected revenue, to support the current operating plan through 2026. Adherex Technologies (NASDAQ:FENC) executives said Fennec Pharmaceuticals entered 2026 with stronger commercial momentum for PEDMARK, reporting higher first-quarter sales, positive operating cash flow and early signs that recent sales force investments are increasing demand. On the company’s first-quarter 2026 earnings call, Chief Executive Officer Jeffrey S. Hackman called 2026 “a defining period” for Fennec, citing progress in commercial execution, clinical interest in PEDMARK and the company’s financial position. PEDMARK is approved for pediatric patients one month of age and older with localized, non-metastatic solid tumors to reduce the risk of cisplatin-induced ototoxicity, or permanent hearing loss. → Rocket Lab Just Hit a New All-Time High—Time to Buy or Let It Breathe? Chief Financial Officer Robert Andrade said net product sales totaled $15.1 million in the first quarter, compared with $8.8 million in the prior-year period, an increase of approximately 73%. Andrade said the quarter marked the sixth consecutive quarter of net product sales growth since new commercial leadership took over. Chief Commercial Officer Terry Evans, participating in his first Fennec earnings call, said the company’s first-quarter performance reflected benefits from “key strategic enhancements” made across the commercial organization. In late 2025, Fennec launched an initiative called Projec...

TranscriptFY2026 Q12026-05-14

FY2026 Q1 earnings call transcript

Earnings source - 101 paragraphs
Operator

Good morning, ladies and gentlemen, and welcome to the Fennec Pharmaceuticals First Quarter 2026 Earnings and Corporate Update Conference Call. At this time, all participants are in a listen-only mode. Later, we will conduct a question and answer session, and instructions on how to participate will be given at that time. As a reminder, today's conference call is being recorded. I would now like to turn the conference over to Fennec's Chief Financial Officer, Robert Andrade. Please begin.

Robert Andrade

Thank you, operator, and good morning, everyone. Thank you for joining us. We are pleased to host Fennec Pharmaceuticals First Quarter 2026 Earnings Conference Call today, during which we will review our financial results as well as provide a general business update. Joining me from Fennec this morning is our Chief Executive Officer and board member, Jeffrey S. Hackman. I am also pleased to welcome our Chief Commercial Officer, Terry Evans, who is joining our earnings call for the first time.

Robert Andrade

Terry is a seasoned commercial and operations leader with a proven track record for delivering significant revenue growth and leading high-performing teams. Terry's industry experience spans all facets of commercial operations, including sales management, operations, market access, trade, specialty pharmacy, and data analytics. He has more than 25 years of commercial leadership experience with companies including Currax Pharmaceuticals, Horizon Therapeutics, and Medesis.

Robert Andrade

Since joining Fennec in the fourth quarter of 2024, Terry has played a pivotal role in reshaping and strengthening our commercial organization. He has helped to sharpen our execution, enhance our field presence, and position the team to capitalize on the opportunities ahead.

Robert Andrade

Later in the call, Terry will speak to how recent efforts will support Fennec's next phase of growth. Our Chief Medical Officer, Dr. Pierre Sayad, will join us for the Q&A portion of today's call. Before we begin, I would like to remind you that during this call, the company will be making forward-looking statements that are subject to risks and uncertainties that may cause actual results to differ from the results discussed in the forward-looking statements.

Robert Andrade

References to these risks and uncertainties are made in today's press release and disclosed in the company's periodic and current event filings with the United States Securities and Exchange Commission. In addition, any forward-looking statements made on this call represent our views only as of today and should not be relied upon as representing our views as of any subsequent date.

Robert Andrade

We specifically disclaim any obligation to update or revise any forward-looking statements. This conference call is being recorded for audio rebroadcast on Fennec's website, www.fennecpharma.com, where it will be available for the next 30 days. I will now turn the call over to Jeff Hackman.

Jeffrey S. Hackman

Thank you, Robert. Good morning, everyone. Thanks for joining the call here today. We are encouraged by our strong start to the year and believe 2026 is a defining period for Fennec. Our conviction is rooted in the progress across many multiple fronts. We've made important strategic enhancements to our business for 2026 that are strengthening our execution across the organization and positions us to continue to build momentum as the year unfolds.

Jeffrey S. Hackman

On the commercial front, we're seeing encouraging early indicators, including positive experiences through our full-service patient support program, Fennec HEARS, as well as trends that support our confidence in the opportunity ahead. Terry will provide more color on those dynamics shortly. Beyond commercial execution, we continue to be encouraged by growing clinical interest in PEDMARK and its broader potential.

Jeffrey S. Hackman

We are pleased to have recently announced a third investigator-initiated study with the University of Arizona Cancer Center to evaluate PEDMARK in adolescent and young adults, or AYA, and adult patients in head and neck and testicular cancers receiving cisplatin. The news follows recent initiations of two other institution-led clinical studies with Tampa General Hospital Cancer Institute and City of Hope.

Jeffrey S. Hackman

We believe that the data insights generated through these studies and others to come will help support broader clinical adoption of PEDMARK to prevent ototoxicity in AYA and adult cancer patients receiving cisplatin-based treatments. Additionally, four abstracts from key opinion leaders evaluating the utility of PEDMARK in preventing cisplatin-induced ototoxicity or permanent hearing loss were accepted for the presentation at this year's ASCO annual meeting.

Jeffrey S. Hackman

Collectively, these studies are continuing to the momentum and the growing body of evidence supporting potential use of PEDMARK in new patient populations and tumor types. As a reminder, PEDMARK is currently approved for pediatric patients one month of age and older with localized non-metastatic solid tumors and is also recognized by the National Comprehensive Cancer Network with a 2A recommendation for use in AYA patients. With regards to Japan, we had a positive informal PMDA meeting earlier this quarter.

Jeffrey S. Hackman

We continue to be in conversations and to explore partnering opportunities in that region. In summary, we're making meaningful progress across the drivers that matters most to our long-term success, expanding clinical momentum, strengthening commercial execution, and maintaining a solid financial foundation. Taken together with what we are observing early in Q2, we believe we are well-positioned to deliver sustained growth throughout this year.

Jeffrey S. Hackman

With that, I will turn it over to Terry for a detailed commercial update.

Terry Evans

Thank you, Jeff. As Jeff just noted, we're encouraged by the momentum we're seeing in the business and believe our first quarter performance reflects the benefits of the key strategic enhancements we've made across the commercial organization. In late Q4 2025, we launched an initiative called Project Ignite. This was a strategic decision based on successful cross-functional initiatives put in place at the start of 2025.

Terry Evans

Building on the shared insights and strong commercial execution, we used data to evaluate opportunities to optimize both reach and frequency. Our Q1 investment in 14 new territories and four frontline managers expanded our ability to engage healthcare professionals, support adoption, and drive sustained momentum across priority markets. Much of the quarter involved the foundational work required to bring those investments fully online, recruiting and onboarding new talent, completing training, and integrating these team members into our commercial model.

Terry Evans

The recruitment and onboarding process concluded at our national meeting in early March. This was an important milestone to align the expanded organization around our strategy, sharpen execution, and ensure the team entered the field equipped and ready to execute. There is a natural ramp period with any field force expansion, and we view much of Q1 as laying that groundwork.

Terry Evans

The expansion of our customer-facing team has allowed us to reach with greater frequency a larger prescriber target base, increasing from 1,300 to now over 5,000 targets. We know the AYA market is promotionally sensitive and effectively communicating the unmet need around CIO is our number one priority. This creates a pathway for practices to help change the standard of care for all appropriate patients receiving cisplatin.

Terry Evans

We believe we're executing in Q2 with a strengthened commercial footprint that is now positioned to drive greater impact through increased reach, frequency, and account penetration. Importantly, we're already seeing encouraging signs from these investments through our HCP targeting efforts. To bring our cross-functional model to life, one recent example illustrates how coordinated engagement can translate into adoption over time.

Terry Evans

About a year ago, our medical team initiated engagement with a KOL from a leading academic center who was familiar with CIO, but not aware of PEDMARK as a preventative treatment option. Through multiple scientific exchanges and participation in a sponsored program at ASCO GU alongside the Testicular Cancer Awareness Foundation, awareness evolved into meaningful engagement. More recently, that relationship was transitioned from medical to field sales.

Terry Evans

A newly deployed territory manager with our key account director introduced Fennec HEARS, which facilitated this KOL's identification and treatment of his first testicular cancer patient for home infusion. Since then, the engagement is actively expanding across the institution with multiple physicians across tumor types now positioned to prescribe and treat more than 20 patients with PEDMARK. In parallel, we're working collaboratively on order sets and EMR integration.

Terry Evans

This example highlights a key principle. Durable growth stems from persistent cross-functional engagement across medical, sales, market access, and patient support services. Another example of significant progress is through our market access initiatives, specifically in terms of engaging with GPOs. One of the fastest-growing oncology aggregators in the U.S. has partnered with us to integrate PEDMARK throughout their network with order sets and site activations.

Terry Evans

We have ongoing efforts with other organizations to replicate this model that supports a top-down adoption approach, complementing the expansion of our sales force focused on bottom-up activities. At the macro level, we continue to see a healthy mix of both new and existing prescribers. Many established accounts are becoming more comfortable with PEDMARK, contributing to deeper utilization and increased vials per account.

Terry Evans

We view that continued adoption and growing depth of use as an important marker of durable demand. In fact, demand in the first quarter was driven by prescribing in three core tumor types: testicular, cervical, and head and neck cancers, and these remain foundational to our commercial opportunity.

Terry Evans

Another area we would highlight is cross-functional collaboration across all parts of our organization to convert prescription demand into completed therapy. This collaboration comes together through Fennec HEARS, our full-service hub designed to simplify access and support continuity of care by guiding patients and providers through coverage, reimbursement, nurse-led administration, and at-home infusion services. This white glove support and education continue to be a meaningful differentiator as we change the standard of care.

Terry Evans

That coordinated approach is reflected in the operational metrics we're seeing. We continue to see strength in infusion volume and vial utilization. This is reflected in a 48% quarter-over-quarter increase in completed infusions through Fennec HEARS and reinforces our ability to translate prescription demand into completed therapy. From a site of care perspective, we're maintaining a productive mix of approximately 50% from both in-office and at-home infusions, which supports access and flexibility for patients and providers.

Terry Evans

Fennec continues to be an important contributor to momentum in the quarter. Through ongoing operational refinements, we're seeing more patients enter the funnel. Specifically, a higher share of patients are progressing to therapy, as reflected in encouraging conversion rates, which are hitting our benchmark of 80% for the first time. Once on treatment, we continue to see strong adherence trends of approximately 80%, which is a huge improvement from where we were one year ago today.

Terry Evans

With our larger sales footprint, we're able to make substantially more sales calls each day versus previous quarters. Now, as I mentioned before, this is a promotionally sensitive market where reach and frequency make an impact on our business. Early indicators of this success include Fennec HEARS patient record monthly enrollments in April.

Terry Evans

Demand through Fennec HEARS in April alone is more than 50% of the total Fennec HEARS demand for all of Q1. As a result, demand in Q2 is tracking to surpass Q1. Additionally, conversion rates remain above our target of 80%, and key community and academic relationships are opening up to our message of CIO prevention. We remain focused on disciplined execution as we build on this momentum throughout the year. With that, I will now turn the call over to Robert for our financial review.

Robert Andrade

Thank you, Terry. Our press release contains details of our financial results for the first quarter of 2026, which can be viewed on the Investors and Media section of our website. Rather than read through all of those details, my comments today will focus on some key financial results.

Robert Andrade

For the first quarter of 2026, the company recorded net product sales of $15.1 million, compared to $8.8 million in the first quarter of 2025, representing an increase of approximately 73% year-over-year compared with the first quarter of 2025. The first quarter demonstrated continued momentum in delivering PEDMARK to patients, with net product sales up for the sixth consecutive quarter since new commercial leadership took over.

Robert Andrade

We saw record new patient enrollments in the March quarter, and April was our highest demand month ever. On the OpEx side, which we define as R&D and SG&A, excluding stock-based compensation, it was approximately $14 million for the quarter, with a year-over-year increase of approximately $6 million.

Robert Andrade

The increase was on the SG&A with expanded marketing investment and increased commercial headcount supporting PEDMARK growth. Important to note, we expect approximately $50 million in cash OpEx in 2026, with over 60% of those expenses expected in the first half of 2026. Cash and cash equivalents were $40.1 million as of March 31st, 2026. For the quarter, there was an increase of $3.3 million in cash and cash equivalents.

Robert Andrade

The net increase in cash consisted of $2.3 million in operating cash flow and approximately $1 million in proceeds from option exercises. With regard to anticipated milestone payments from our partner, Norgine, we do not anticipate receiving the German milestone payment. We look forward to Norgine's expansion efforts in 2026 as they launch in multiple markets and the potential for the next milestone achievement by the end of 2026.

Robert Andrade

Importantly, we generated positive cash flow in the 1st quarter of 2026. As we grow the business, we anticipate select quarterly swings in the cash position based on collection cycles with customers, and as such, expect the 2nd quarter ending cash to be lower than the 1st quarter.

Robert Andrade

However, we expect the third quarter cash to be positive and to grow the cash the remainder of the year in the second half of 2026. We have tremendous leverage in the business with a predominantly fixed cost base. As our revenue growth continues, we anticipate operating income to grow meaningfully in the quarters to come. Lastly, as stated in our press release, we anticipate that our cash equivalents in investment securities as of March 31st 2026 Combined with projected revenues from PEDMARK, will be sufficient to fund our business based on our current operating plan. Operator, with that, we are now ready to open the call for questions.

Operator

Certainly. As a reminder, to ask a question, please press star one one on your telephone and wait for your name to be announced. To withdraw your question, please press star one one again, and please stand by while we compile our Q&A roster. Our first question will be coming from the line of Madison El-Saadi of B. Riley Securities. Your line is open, Madison.

Madison El-Saadi

Hey, guys. Thanks for taking our question, and, congrats on the quarter. It seems you gave some additional color this quarter on KPIs and performance. Maybe just help us break down really what drove the upside here, if this was predominantly new account adds in 1Q, if it was deepening utilization of your base accounts, or maybe just productivity from sales force, expansion that weren't fully onboarded, as of March. Afterwards, a follow-up.

Jeffrey S. Hackman

Sure. Sure. This is Jeff. Thanks for the question. Yeah, appreciate it, and I'll let Terry comment on a little bit. You know, we talked about execution early on, when I even first got here, a year and a half or so ago and going on. You know, we're starting to see it now. One of the things that we saw with Project Ignite was the ability for us to not only expand our reach, but expand our frequency. That's what we're seeing, and one of the reasons why you're seeing such, you know, significant uptake, especially in a month like April. You know, we can go into a little bit more detail.

Jeffrey S. Hackman

You know, Fennec HEARS is something that drives a lot of the growth here. We see, you know, we see demand all throughout Q1, growing through Fennec HEARS, so that's also exciting for us. You know, I'll let Terry comment a little bit more on some of the growth.

Terry Evans

Yeah, for sure. Thank you for the question. What we're seeing is new starts in Q2 is balanced really between both academic and community. In that balanced approach, utilizing the additional folks that we have, our increased reach and frequency that Jeff mentioned. We're seeing that really present itself in academic and large community, small community practices. We're seeing a nice growth in both AYA and pediatrics. Yeah, we're encouraged by the balance of the year.

Madison El-Saadi

Got it. Thanks, Jeff.

Terry Evans

Do you want to follow up, Madison?

Madison El-Saadi

Yeah. Yes, please. It seems like you've had multiple inbound interests regarding these ISTs. I'm just wondering, you know, why you guys decided to go with the ISTs and the tumor types you did. If we focus just on, say, the AYA adult testicular, you know, what can this practically mean for the company? Is it more of a means of entrenching PEDMARK, increasing awareness, or is it more in the context of tumor expansion? Just curious, if you can comment, if you've seen any revenue come out of these IST institutions. Seems that would be a really tremendous kind of leading indicator of kind of the awareness gap. Thanks.

Jeffrey S. Hackman

Oh, great question again, and I'll kick it over to Pierre, who's sitting here with us today. You know, ISTs are something that are important for a couple of reasons. Number one is it establishes, you know, our position in the space. One of the pushback you'll get from AYA physicians that talk is, "Let me see the data. Let me see some of the data that was generated in this population." As you know, you know, the trials that got PEDMARK approved were trials that were done with the Children's Oncology Group or in the pediatric space.

Jeffrey S. Hackman

That's one of the reasons why we're excited about the testicular data that we're generating through the as well as some of the adult data down the road that are gonna come from these. The second part is and I'll let Pierre talk a little bit more on how this happens inside the institutions. We not only the physicians who are participating in these studies are using the product, but also physicians that are surrounding those physicians. We're seeing that expansion throughout the institution. Pierre, maybe you can comment a little bit on that.

Pierre Sayad

Sure. Sure, Jeff. Thanks for the question. Yes, you know, as the medical team have the conversations around our two phase III clinical trials, as Jeff alluded, those were obviously in the pediatric setting. There's a very natural conversation that happens with our physicians where they say, "Okay, now that I'm really understanding how cisplatin is causing this damage in the cochlea and how PEDMARK can potentially prevent that," they're coming to us with these new and very creative ISTs to test this out in AYA and adult patients.

Pierre Sayad

we're as you know from previous press releases, at least on the three ISTs that have already been announced, these are across tumor types, AYA setting, adult setting, localized tumors, metastatic tumors, and all these ideas are coming directly from the KOLs. we're very excited about all this interest. I think your second question maybe was what do we do with this data? As you can imagine, as the data matures and our dataset expands, we're certainly thinking about potential regulatory conversations, NCCN guidelines submissions, so on and so forth.

Pierre Sayad

I think the third point, just to cover what Jeff said, we absolutely see this very interesting trend of once an IST is activated in a given academic institution, there's so much training, so much conversation that needs to happen that now you have the pharmacists, the nurses, other oncologists, all really on board with PEDMARK. I, you know, we begin to see a little bit of an uptick in commercial use in those institutions.

Jeffrey S. Hackman

Great. Thanks, Pierre.

Madison El-Saadi

Thanks, guys. That's very helpful.

Operator

Our next question will come from the line of Chase Knickerbocker of Craig-Hallum. Your line is open, Chase.

Chase Knickerbocker

Good morning. Thanks for taking the questions. Congrats on the nice quarter here. Could you maybe just share what percentage of your volume or, you know, just some kind of underlying demand metric was driven by the new rep hires over the last couple quarters? How is that productivity trending in Q2? Really just trying, you know, to get to the extent of kind of what to what magnitude those new hires are playing a role in this sequential growth and then when they can be fully productive.

Jeffrey S. Hackman

Yeah. I'll give this over to Terry, but Chase, thanks for the question. It's a good one. The things we're seeing early on April is new patients or I mean coming from new territories, which is exciting. You know, we see a healthy mix both coming from new and existing prescribers. I'm commenting now on, you know, the April numbers that we're seeing. These are established accounts, but which are becoming more comfortable with PEDMARK. Also we're seeing execution in accounts, in new accounts, which is really exciting in places where we've never seen patients before.

Jeffrey S. Hackman

we knew that once we expanded our reach and we expanded the frequency of this, you know, the PEDMARK message, we were gonna see continued adoption through these. Terry, maybe you can comment a little bit.

Terry Evans

Yeah. A couple of things. Jeff's exactly right. There's a significant number of our new territories that had prescriptions or patients that have come through between the time that our national meeting occurred through the end of April. Part of the point that you made, Chase, we actually began the decision of Project Ignite in Q4, and it kinda happened all the way through Q1.

Terry Evans

We trained everybody the first week of March, ended at our national meeting. The effectiveness of these salespeople, the new salespeople really began, you know, call it on March the ninth. As you know, and through years of experience, there's a ramp period of productivity for our sales team.

Terry Evans

We've talked about we've talked about kind of the second half as we get these folks up and running and more productive. Early signs are good. You know. There's a good balance between new accounts and existing accounts and growing patients and prescriptions inside of both of those. You know, we're encouraged that the fact that with the strengthened commercial footprint, we're gonna drive reach and frequency and we're excited that we've been able to deliver six consecutive quarters of strong performance.

Chase Knickerbocker

Helpful. Thank you. Maybe just a couple smaller kinda details. Can you just speak to the kinda stability of the pediatric revenue? Just trying to get a sense for kind of underlying sequential AYA growth. Can you just remind us what percentage of your business at this point, either from a demand or revenue perspective, is flowing through Fennec HEARS? Thank you.

Jeffrey S. Hackman

Yeah. I'll take a couple of the beginning points of this, then I'll give it over to Terry. You know, Chase, we see, you know, We're excited about the business and how it's growing. The Fennec HEARS right now, what we're seeing is, in April alone, about 50% of our business and demand is going through Fennec HEARS.

Jeffrey S. Hackman

That's increasing every day. It increases as we get better at implementation. It increases as physicians wanna add more patients to this. We're continuing to see that. Our pediatric business is growing. It's growing, not at the pace, of course, of AYA, and we've said that before in the past.

Jeffrey S. Hackman

Pediatric business grows because we're getting now into institutions and places where we didn't have the ability to get to in the past with our pediatric business as well. When a pharmacist, for example, becomes comfortable in an academic institution with the product, for example, in the AYA space, we're seeing now uptake in the pediatric space as well because of that ability to be comfortable with the product. Whether we get in there through AYA or pediatric, for me, it doesn't really matter. It's the opportunity to be able to access these patients. Terry?

Terry Evans

Yeah. Jeff, I agree. Chase, we're growing in both pediatrics and AYA. you know, Fennec's, as Jeff mentioned, is, roughly about 50%. it's important to note that even though we grow pediatrics and we're growing the AYA, PEDMARK is weight-based. just AYA represents, you know, 20-plus thousand patients with a high survival rate that take high-dose cisplatin. the AYA would be expected to outpace pediatrics even though the pediatric space is growing. you know, in both of those things, I think we, I think we're taking a balanced approach, which again, kinda leads us to six quarters of strong growth.

Chase Knickerbocker

Thanks, Dave.

Operator

Thank you. Our next question will come from the line of David Amsellem of Piper Sandler & Co. Your line is open, David.

Alex von Riesemann

Hi. Good morning. This is Alex von Riesemann on for David. Thanks for taking our question. My first question is just, how are you thinking about life cycle management for PEDMARK? Secondly, what is your appetite for acquiring another asset? Thank you.

Jeffrey S. Hackman

Yeah, it's a great question. you know, I'll touch on it on the, you know, the life cycle and I can turn to Pierre on this. you know, you're starting to see a little bit of that life cycle management come into play with the ISTs. you know, we talk about three kind of groups of patients for our business. It's the pediatric, and we talk about AYA, but there's also adult.

Jeffrey S. Hackman

When you think of where cisplatin is given, it's given across not only these three areas, but it's also given to both localized and metastatic. now you're starting to see us start to grow the opportunity to develop data and expand it from a life cycle management standpoint into these other types of populations. The metastatic population, for example.

Jeffrey S. Hackman

Can this product be given there, and be effective in these patients? In the adult patients, in the head and neck space. You're starting to see all of this, and we have got more opportunities to be able to do that in other areas. Maybe, Pierre, you can touch on those.

Pierre Sayad

Sure. That's exactly right, Jeff. As I touched upon earlier, you know, the ISTs are beginning to mature, and we're seeing the data come through, so that obviously is going to open doors into metastatic indications. We've had a tremendous interest from multiple academic institutions putting forth very creative new ISTs in the head and neck space.

Pierre Sayad

As I mentioned, alluded to before, we have our sights set on possible NCCN designation criteria for head and neck, and cervical is also a very robust area in terms of interest. As the data matures, that'll define our strategy to expand, whether it's with regulatory meaningfulness or NCCN guidelines.

Jeffrey S. Hackman

Yeah. As related to the second part of your question, you know, looking at other products and bringing in, you know, other opportunities, we continue to be open to that. As you know now, we've expanded our commercial team significantly. We've expanded the organization and put resources in places now that you could start to expect a potential opportunity to be able to layer in some additional, you know, products, for example. Yeah, we continue to be open to that, and that's something that, you know, we're looking at as well. Thank you.

Operator

Our next question will be coming from the line of Ram Selvaraju of H.C. Wainwright. Your line is open, Ram.

Katie Degen

Hi. Good morning. This is Katie on for Ram. I guess I'm wondering, what is the typical profile of a high-volume prescriber for PEDMARK at this point? Are those high-volume prescribers predominantly NCI cancer centers? Are they more community oncologists? how many of those physicians are there in the U.S.?

Jeffrey S. Hackman

Yeah, we talked about. That's a good question. Appreciate it. Terry mentioned that we're targeting about 5,400 folks with our new team, expanded up from, you know, from just a little bit over 1,000. And those break out. Typically, we see the concentration of our uptake in both academic and community settings. Our strategy, you know, as we get into this, is designed to engage both academic centers and also community practices, and we're seeing a really good balance between both. Maybe, Terry, you can comment on that.

Terry Evans

No, I think you're exactly right. With our greater region frequency, what we're seeing, we're seeing new starts from academic and community settings. One of the important things that I may or may not have said, which is PEDMARK's a long, it's a long play sometimes, where it takes medical, it takes sales, it takes market access, it takes, you know, patient support services, lots of these, you know, cross-functional teams to kind of pull it through. The need in academic is slightly different than the need in community. I'd mentioned this before, we're taking a nice balanced approach and activating both sides of them. Thank you.

Katie Degen

Excellent. If I could sneak in one more question.

Jeffrey S. Hackman

Sure.

Katie Degen

Do you guys have an idea of how many additional investigator-initiated trials you're gonna have starting this year? Could any of those outcomes give you avenues to label expansion?

Jeffrey S. Hackman

Sure, it's a good question. You know, we get, soon as we put out, you know, your first press release, you know, you start to see, significant interest come in, right? Well, 'cause, you know, they see that we have, you know, our doors are open for partnerships. Let me let Pierre comment on that a little bit. You know, again, the doors, you know, there's a limit to how many we're gonna do, I can tell you that. You know, there are some really interesting ones that we've been talking about. Pierre, maybe you can comment on that.

Pierre Sayad

Sure, sure. I'm smiling a little bit at the question. I mean, the we're really excited, very encouraged. You know, when you have the amount of interest that we've had from the top academic institutions for new ISTs, it's always a great sign. In terms of how many are we expecting to see, I can't comment on that. There will hopefully be more press releases here soon. I think the point, though, that I wanna make is these are not, I'll use the word haphazard. You know, we have a very strong strategy as to which ones we're approving and which ones we are not.

Pierre Sayad

Ultimately, there will be efforts to combine data, et cetera, do some pooled analyses, with very specific purposes, again, as I mentioned, for regulatory enabling conversations.

Jeffrey S. Hackman

Perfect. Thanks, Pierre.

Operator

Our next question-

Katie Degen

Thank you, guys

Operator

will be coming from the line of Sudan Loganathan of Stephens. Your line is open.

Sudan Loganathan

Thanks. Good morning, and we appreciate the update and the great progress. My first question, I wanted to ask what your internal pipeline looks like to target new patient populations also treated with platinum-based chemotherapy, such as ovarian cancer, bladder cancer, colorectal cancer, and even non-small cell or small cell lung cancers. I believe those areas will start getting into more into the AYA population. I'm curious to see what you view out of those maybe or others, to be the next low-hanging fruit.

Jeffrey S. Hackman

Sure. Thanks, Sudan. That's a good question. You know, we, you know, we go where cisplatin is given, right? We know that there's certain tumor types that are obviously a target for us, and in that space of where, you know, these patients receive therapy, you know, with cisplatin. I'll let Pierre comment on the potential new ones. You know, we see as an opportunity, obviously, testicular, because cisplatin has done so. It is the gold standard. It's something that there's a lot of cisplatin that's given, and we see a big impact of CIO in that space.

Jeffrey S. Hackman

There are others that physicians have come to us throughout the, you know, our timeframe as we expand because they're using a lot of cisplatin in, you know, in cervical and head and neck and other places. We see that expansion in places like that. Maybe, Pierre, you can talk about why we see that.

Pierre Sayad

Yeah. As we've covered before, there's a strong foothold, if you will, interest that has come through for head and neck, testicular, cervical. We are absolutely having a lot of conversations in those additional areas that you mentioned as well, bladder, as well as lung. I think it's basically what Jeff said.

Pierre Sayad

The mechanism by which cisplatin, A, combats the tumor but then also defeats and kills these very sensitive cochlear hair cells is the same across all these tumors. Wherever cisplatin goes, PEDMARK absolutely has a strong potential of helping those patients. Yes, you're absolutely right? It's head and neck, cervical, testicular, lung, bladder, and there's probably a few more that we could rattle off here.

Pierre Sayad

those are all absolutely, big targets for PEDMARK.

Sudan Loganathan

Great. Secondly, if I can squeeze one more in. You know, could we get more details on how the PEDMARK launches are going? What are the primary sticking points, and when do you anticipate revenues from there maybe to start actually moving the needle for the business? Thanks again for all the details.

Jeffrey S. Hackman

Yeah. You know, we're enthusiastic about what we're seeing with Norgine. It's, you know, this is the year we'll see significant growth in Norgine throughout their territories, and we're starting to see obviously many countries as Robert said. Maybe you can comment a little bit on some of the growth that we're seeing through Fennec here. I mean, through Norgine.

Robert Andrade

Yeah. PEDMARQCY for 2026 will be launched in multiple markets, almost double-digit type markets. This is the year where the foundation gets laid. I think an important point there is not only our royalties, which start in the mid-teens, as they grow those sales, but also the milestones. If you think of the over $200 million in milestones, at least half of those are tied purely to achieving certain sales. We look forward to giving you updates, but this is 2026 is the year where we see the ramp starting.

Sudan Loganathan

Great. Thank you so much. Congrats again on a great quarter.

Operator

And now with that-

Jeffrey S. Hackman

Thank you. Yep.

Operator

I would now like to turn the call back to Jeff for closing remarks.

Jeffrey S. Hackman

Perfect. Well, thanks, and great questions and really appreciate everybody here, you know, attending today. In closing, we believe our first quarter performance reflects meaningful momentum across the business and reinforces our confidence in 2026 as an important year for Fennec. With strong execution underway in Q2 and multiple catalysts ahead, we remain focused on delivering sustained value. Thank you all again for your continued interest and support. We appreciate it. Take care.

Operator

This concludes today's conference. Thank you for your participation. You may now disconnect.

Investor releaseQuarter not tagged2026-05-07

Fennec Pharmaceuticals to Report First Quarter 2026 Financial Results on May 14, 2026

GlobeNewswire

RESEARCH TRIANGLE PARK, N.C., May 07, 2026 (GLOBE NEWSWIRE) -- Fennec Pharmaceuticals Inc. (NASDAQ: FENC; TSX: FRX), a commercial stage specialty pharmaceutical company, today announced that the Company will release its first quarter 2026 financial results before the opening of the U.S. financial markets on Thursday, May 14, 2026. Management will host a conference call and webcast that day to discuss the Company’s financial and business results. Conference Call & Webcast Detail: Date: Thursday, May 14, 2026 Time: 8:30 a.m. Eastern Time Webcast Link: https://edge.media-server.com/mmc/p/2iptdco4 Participant Link: https://register-conf.media-server.com/register/BIaa4b518aeb974d02873eccf8f56d92f3 To access the live webcast link, log onto www.fennecpharma.com and proceed to the News & Events/Event Calendar page under the Investors & Media heading. Please connect to the company’s website at least 15 minutes prior to the conference call to ensure adequate time for any software download that may be required to listen to the webcast. A webcast replay of the conference call will also be archived on www.fennecpharma.com for thirty days. About Fennec Pharmaceuticals Fennec Pharmaceuticals Inc. is a specialty pharmaceutical company committed to the fight against ototoxicity in cancer patients who receive cisplatin-based chemotherapy. Fennec is focused on the commercialization of PEDMARK® to reduce the risk of platinum-induced ototoxicity in cancer patients. PEDMARK received FDA approval in September 2022 and European Commission approval in June 2023 and United Kingdom (U.K.) approval in October 2023 under the brand name PEDMARQSI. In March 2024, Fennec entered into an exclusive licensing agreement under which Norgine Pharmaceuticals Ltd., a leading European specialist pharmaceutical company, will commercialize PEDMARQSI® in Europe, U.K., Australia and New Zealand. PEDMARK has received Orphan Drug Exclusivity in the U.S. and.; PEDMARQSI has received Pediatric Use Marketing Authorization in Europe, which includes eight years plus two years of data and market protection. Further, Fennec has patents providing protection for PEDMARK until 2039 in both the U.S. and internationally. For more information, please visit www.fennecpharma.com and follow on LinkedIn. For further information, please contact: Investors: Robert Andrade Chief Financial Officer Fennec Pharmaceuticals Inc....

Investor releaseQuarter not tagged2026-04-16

Wedbush Refines Fennec Pharmaceuticals Estimates Ahead of Q1 Earnings

MT Newswires

Wedbush is refining its its 2026 estimates for Fennec Pharmaceuticals (FRX.TO) ahead of the company

Investor releaseQuarter not tagged2026-03-25

Fennec Pharmaceuticals Inc. Q4 2025 Earnings Call Summary

Moby

Achieved record net product sales of $44.6 million in 2025, a 50% year-over-year increase driven by expanding active patient counts and new account acquisition. Strategic pivot toward the Adolescent and Young Adult (AYA) market, which management identifies as ten times larger than the core pediatric segment. Enhanced commercial execution through a 70% conversion rate in the Fennec HEARS program, up from 50% in Q1, by reducing administrative and reimbursement friction. Strengthened financial health by eliminating all debt and raising $42 million in net proceeds, resulting in the strongest balance sheet in corporate history. Transitioned from a pediatric-only focus to a broader oncology supportive care model by initiating studies in testicular and head and neck cancers. Optimized the cost structure by exiting European operations following the Norgine partnership, allowing for redeployment of capital into U.S. commercial expansion. Anticipate generating positive cash flow in Q1 2026, supported by early collection of receivables that were delayed in the fourth quarter. Projecting cash operating expenses to increase to approximately $50 million in 2026 to fund expanded field force reach and frequency. Expect material revenue contributions from the Norgine partnership in the second half of 2026 as launches expand to 8-10 additional European countries. Guidance methodology focuses on a high-leverage model where every 100 additional patients can contribute approximately $30 million in net revenue. Prioritizing a partnership for the Japanese market following positive Phase II/III results to initiate the local regulatory registration process. Settled patent litigation with Cipla, securing market exclusivity for PEDMARK until September 1, 2033, and eliminating millions in annual legal expenses. Addressed historical physician concerns regarding cisplatin interference by citing long-term data showing no difference in overall survival over 5-8 years. Identified the AYA testicular cancer segment as the largest immediate opportunity, with an addressable market exceeding 20,000 patients annually. Reported 95% to 100% reimbursement rates across the top three national insurance plans, mitigating previous concerns regarding AYA market access. Our analysts just identified a stock with the potential to be the next Nvidia. Tell us how you invest and we'll show you why it's our #1...

As of 2026-05-30 • Updated weeklySource: Earnings sourceIngestion runbook