B+
Bull case
25%
Probability
Target price
$48.00
Analysis reference price unavailable
Analysis 2026-08-13 · RankAlpha Sentiment Codex
STOK
Stoke TherapeuticsBNasdaq / Pharmaceuticals, Biotechnology & Life Sciences
Last Price
Quote time unavailable
Current thesis
Rapid EMPEROR enrollment, no reported treatment discontinuations, supportive longitudinal open-label data, a planned regulatory sequence, and approximately $420 million of pro forma cash support the possibility of a successful zorevunersen launch path. The STK-002 program adds longer-term platform optionality.
Posture
Constructive
Lead driver
Sentiment
What changed
Sentiment remains the lead driver in the composite, 7D delta +12.4.
What can break
Cash runway depends on execution, development costs, and potential partner milestone assumptions.
Momentum
25
Value
41
Sentiment
82
Setup hits (3d)
0 · Net Neutral
AI TargetsBase $34.00 · Bull $48.00 · Bear $20.00Analysis 2026-08-13; returns require an exact persisted reference.
Data freshness
Prices
Unavailable: Price unavailable
Fundamentals
As of 2026-08-17 • Vendor: Data Vendor v1
Scores
As of 2026-09-08 • Model: HYBRID_IC_RP
AI Memo
As of 2026-08-13 • Model: RankAlpha Sentiment Codex
Investment thesisAs of 2026-09-08
Investment thesis
As of 2026-09-08
Grade is the composite factor band; factor scores use a 0–100 scale. Confidence describes evidence quality, not a probability of return. Score date: 2026-09-08. Definitions
Supporting evidence
What
Grade B · Constructive
Confidence Medium · Net Neutral
Target $46.46
Why
Momentum25 · Δ7d -36.4
Value41 · Δ7d -0.0
Sentiment82 · Δ7d +12.4
So what
Strength-led posture (Net Neutral). Favor watchlist adds and disciplined entries.
Confirming evidence
- • Sentiment remains the lead driver in the composite, 7D delta +12.4.
Contradictions & invalidation
- • Cash runway depends on execution, development costs, and potential partner milestone assumptions.
- • FDA alignment on the statistical analysis plan and rolling NDA package could affect timing or approval prospects.
- • The core value driver remains an unreported, blinded Phase 3 outcome.
Catalyst clock
2026-11-11
Post-earnings update: EMPEROR enrollment complete and regulatory path advances
Lead driver: Sentiment · See AI snapshot
Momentum
25
9% active weight
Current posture
7d trendSoftening
Δ7d
-36.4
Δ21d
-19.9
Value
41
28% active weight
Current posture
7d trendFlat
Δ7d
-0.0
Δ21d
-7.8
Sentiment
82
62% active weight
Current posture
7d trendImproving
Δ7d
+12.4
Δ21d
+6.7
Why this grade
Composite grade B. Momentum 25.1 / Value 41.2 / Sentiment 82.4
Scenario snapshot
Scenario probability is memo-authored likelihood, not forecast certainty. Targets belong to the analysis dated 2026-08-13. Scenario method
Most likely
B
Base case
50%
Probability
Target price
$34.00
Analysis reference price unavailable
Analysis 2026-08-13 · RankAlpha Sentiment Codex
B-
Bear case
25%
Probability
Target price
$20.00
Analysis reference price unavailable
Analysis 2026-08-13 · RankAlpha Sentiment Codex
Fundamentals (TTM)As of 2026-08-17
Fundamentals (TTM)
As of 2026-08-17
Market Cap
$2.07B
Beta
1.10
Shares Out
64.53M
P/E (TTM)
49.3
P/S (TTM)
9.04
P/FCF (TTM)
35.50
Rev YoY
-32.5%
EPS YoY
+132.0%
Gross Margin
+84.7%
Op Margin
-809.7%
Net Debt
-$281.02M
Current Ratio
7.69
As of 2026-09-08 • Updated nightlySource: Internal modelMethods & Data