B+
Bull case
25%
Probability
Target price
$6.50
Analysis reference price unavailable
Analysis 2026-09-25 · RankAlpha Sentiment Codex
ANNX
AnnexonDNasdaq / Pharmaceuticals, Biotechnology & Life Sciences
Last Price
Quote time unavailable
Current thesis
Three program-specific milestones before year-end could validate Annexon's C1-focused pipeline. The company reported $209.2 million of cash and short-term investments at June 30 and, including access to its credit facility, projected runway into 2028 [#SEC-8K-2026-08-12].
Posture
Defensive
Lead driver
Sentiment
What changed
Sentiment remains the lead driver in the composite, 7D delta -13.2.
What can break
A negative or ambiguous ARCHER II month-15 readout could sharply impair the largest near-term asset thesis.
Momentum
19
Value
41
Sentiment
57
Setup hits (3d)
0 · Net Neutral
AI TargetsBase $3.80 · Bull $6.50 · Bear $1.50Analysis 2026-09-25; returns require an exact persisted reference.
Data freshness
Prices
Unavailable: Price unavailable
Fundamentals
As of 2026-10-23 • Vendor: Data Vendor v1
Scores
As of 2026-10-26 • Model: HYBRID_IC_RP
AI Memo
As of 2026-09-25 • Model: RankAlpha Sentiment Codex
Investment thesisAs of 2026-10-26
Investment thesis
As of 2026-10-26
Grade is the composite factor band; factor scores use a 0–100 scale. Confidence describes evidence quality, not a probability of return. Score date: 2026-10-26. Definitions
Supporting evidence
What
Grade D · Defensive
Confidence Medium · Net Neutral
Target $17.00
Why
Momentum19 · Δ7d +1.0
Value41 · Δ7d -0.0
Sentiment57 · Δ7d -13.2
So what
Weak posture (Net Neutral). Prioritize risk control and patience.
Confirming evidence
- • Sentiment remains the lead driver in the composite, 7D delta -13.2.
Contradictions & invalidation
- • A negative or ambiguous ARCHER II month-15 readout could sharply impair the largest near-term asset thesis.
- • ANX1502 remains proof-of-concept-stage, so biomarker findings may not establish clinical benefit.
- • ARCHER II efficacy remains unproven in Phase 3, the additional month-24 endpoint may prolong the investment decision, and BLA filing does not imply approval.
Catalyst clock
2026-11-30
ANX1502 proof-of-concept update
Lead driver: Sentiment · See AI snapshot
Momentum
19
8% active weight
Current posture
7d trendFlat
Δ7d
+1.0
Δ21d
+13.1
Value
41
47% active weight
Current posture
7d trendFlat
Δ7d
-0.0
Δ21d
-0.4
Sentiment
57
45% active weight
Current posture
7d trendSoftening
Δ7d
-13.2
Δ21d
+3.9
Why this grade
Composite grade D. Momentum 19.2 / Value 40.6 / Sentiment 57.4
Scenario snapshot
Scenario probability is memo-authored likelihood, not forecast certainty. Targets belong to the analysis dated 2026-09-25. Scenario method
Most likely
B
Base case
45%
Probability
Target price
$3.80
Analysis reference price unavailable
Analysis 2026-09-25 · RankAlpha Sentiment Codex
B-
Bear case
30%
Probability
Target price
$1.50
Analysis reference price unavailable
Analysis 2026-09-25 · RankAlpha Sentiment Codex
Fundamentals (TTM)As of 2026-10-23
Fundamentals (TTM)
As of 2026-10-23
Market Cap
$710.92M
Beta
1.17
Shares Out
189.58M
P/E (TTM) · Derived
-2.8
P/S (TTM)
-
P/FCF (TTM) · Derived
-3.43
Rev YoY
-
EPS YoY
-19.9%
Gross Margin
-
Op Margin
-
Net Debt
-$212.14M
Current Ratio
5.53
As of 2026-10-26 • Updated nightlySource: Internal modelMethods & Data